Valacyclovir and Logorrhea - a phase IV clinical study of FDA data


We study 35,581 people who have side effects when taking Valacyclovir. Logorrhea is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Velcade and have Multiple myeloma.

The phase IV clinical study analyzes which people take Valacyclovir and have Logorrhea. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

35,581 people reported to have side effects when taking Valacyclovir.
Among them, 11 people (0.03%) have Logorrhea.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is used in genital herpes. Currently, eHealthMe is studying from 36,385 Valacyclovir users.

What is Logorrhea?

Logorrhea is found to be associated with 1,010 drugs and 566 conditions by eHealthMe. Currently, we are studying 4,019 people who have Logorrhea.

Number of Valacyclovir and Logorrhea reports submitted per year:

Could Valacyclovir cause Logorrhea?

Time on Valacyclovir when people have Logorrhea *:

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Logorrhea when taking Valacyclovir *:

  • female: 70 %
  • male: 30 %

Age of people who have Logorrhea when taking Valacyclovir *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 22.22 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 44.44 %

Common drugs people take besides Valacyclovir *:

  1. Velcade: 4 people, 36.36%
  2. Nadolol: 3 people, 27.27%
  3. Prednisone: 1 person, 9.09%
  4. Ondansetron: 1 person, 9.09%
  5. Oncovin: 1 person, 9.09%
  6. Norethindrone: 1 person, 9.09%
  7. Nifedipine: 1 person, 9.09%
  8. Mycamine: 1 person, 9.09%
  9. Methotrexate: 1 person, 9.09%
  10. Levofloxacin: 1 person, 9.09%

Common side effects people have besides Logorrhea *:

  1. Speech Disorder: 7 people, 63.64%
  2. Leukocytosis (increased white blood cells): 5 people, 45.45%
  3. Dry Mouth: 4 people, 36.36%
  4. Psychomotor Hyperactivity (feelings of extreme restlessness): 4 people, 36.36%
  5. Memory Loss: 4 people, 36.36%
  6. Fall: 4 people, 36.36%
  7. Thrombocytopenia (decrease of platelets in blood): 4 people, 36.36%
  8. Acute Kidney Failure: 4 people, 36.36%
  9. Dehydration (dryness resulting from the removal of water): 4 people, 36.36%
  10. Constipation: 4 people, 36.36%

Common conditions people have *:

  1. Multiple Myeloma (cancer of the plasma cells): 4 people, 36.36%
  2. Lymphoma (cancer that begins in immune system cells): 1 person, 9.09%
  3. Gastric Ulcer (stomach ulcer): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Valacyclovir and have Logorrhea?

Check whether Logorrhea is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Valacyclovir side effects by duration, gender and age:

Logorrhea treatments and more:

Common drugs associated with Logorrhea:

All the drugs that are associated with Logorrhea:

Common conditions associated with Logorrhea:

All the conditions that are associated with Logorrhea:

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride (the active ingredients of Valacyclovir) and Valacyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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