Valacyclovir and Pneumococcal infection - a phase IV clinical study of FDA data


Pneumococcal infection is reported only by a few people who take Valacyclovir.

The phase IV clinical study analyzes which people take Valacyclovir and have Pneumococcal infection. It is created by eHealthMe based on reports of 28,161 people who have side effects while taking Valacyclovir from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 18, 2023

28,161 people reported to have side effects when taking Valacyclovir.
Among them, 2 people (0.01%) have Pneumococcal infection.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 28,906 Valacyclovir users for its effectiveness, alternative drugs and more.

What is Pneumococcal infection?

Pneumococcal infection (infection caused by streptococcus pneumoniae) is found to be associated with 403 drugs and 207 conditions by eHealthMe.

Number of Valacyclovir and Pneumococcal infection reports submitted per year:

Could Valacyclovir cause Pneumococcal infection?

Gender of people who have Pneumococcal infection when taking Valacyclovir *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Pneumococcal infection when taking Valacyclovir *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 50 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 50 %

Common drugs people take besides Valacyclovir *:

  1. Velcade: 1 person, 50.00%
  2. Vasotec: 1 person, 50.00%
  3. Prednisolone: 1 person, 50.00%
  4. Nadolol: 1 person, 50.00%
  5. Leucovorin Calcium: 1 person, 50.00%

Common side effects people have besides Pneumococcal infection *:

  1. C-Reactive Protein Increased: 2 people, 100.00%
  2. Weakness: 1 person, 50.00%
  3. Constipation: 1 person, 50.00%
  4. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1 person, 50.00%
  5. Haemoglobin Decreased: 1 person, 50.00%
  6. Gait Disturbance: 1 person, 50.00%
  7. Fall: 1 person, 50.00%
  8. Dry Mouth: 1 person, 50.00%
  9. Dehydration (dryness resulting from the removal of water): 1 person, 50.00%
  10. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 1 person, 50.00%

Common conditions people have *:

  1. Multiple Myeloma (cancer of the plasma cells): 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Valacyclovir and have Pneumococcal infection?

Check whether Pneumococcal infection is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Pneumococcal infection and when was it recovered:

Expand to all the drugs that have ingredients of valacyclovir hydrochloride:

Alternative drugs to, pros and cons of Valacyclovir:

Common Valacyclovir side effects:

Browse all side effects of Valacyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Pneumococcal infection treatments and more:

COVID vaccines that are related to Pneumococcal infection:

All the drugs that are associated with Pneumococcal infection:

All the conditions that are associated with Pneumococcal infection:

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride (the active ingredients of Valacyclovir) and Valacyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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