Valchlor and Musculoskeletal stiffness - a phase IV clinical study of FDA data

Summary:

Musculoskeletal stiffness is found among people who take Valchlor, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Valchlor and have Musculoskeletal stiffness. It is created by eHealthMe based on reports of 2,462 people who have side effects when taking Valchlor from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

2,462 people reported to have side effects when taking Valchlor.
Among them, 14 people (0.57%) have Musculoskeletal stiffness.

What is Valchlor?

Valchlor has active ingredients of mechlorethamine hydrochloride. eHealthMe is studying from 2,463 Valchlor users for its effectiveness, alternative drugs and more.

What is Musculoskeletal stiffness?

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves) is found to be associated with 2,464 drugs and 1,848 conditions by eHealthMe.

Number of Valchlor and Musculoskeletal stiffness reports submitted per year:

Could Valchlor cause Musculoskeletal stiffness?

Gender of people who have Musculoskeletal stiffness when taking Valchlor *:

female: 64.29 %
male: 35.71 %

Age of people who have Musculoskeletal stiffness when taking Valchlor *:

Common drugs people take besides Valchlor *:

Valsartan And Hydrochlorothiazide: 3 people, 21.43%
Lipitor: 2 people, 14.29%
Advair Hfa: 1 person, 7.14%

Common side effects people have besides Musculoskeletal stiffness *:

Dry Skin: 6 people, 42.86%
Pain In Extremity: 6 people, 42.86%
Joint Stiffness: 4 people, 28.57%
Pain Of Skin: 4 people, 28.57%
Application Site Pruritus (application site severe itching of the skin): 4 people, 28.57%
Application Site Warmth: 4 people, 28.57%
Back Pain: 4 people, 28.57%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 4 people, 28.57%
Tenderness (pain or discomfort when an affected area is touched): 4 people, 28.57%
Application Site Discoloration: 4 people, 28.57%

Common conditions people have *:

Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 9 people, 64.29%

* Approximation only. Some reports may have incomplete information.

Do you take Valchlor and have Musculoskeletal stiffness?

Check whether Musculoskeletal stiffness is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Musculoskeletal stiffness and when was it recovered:

Musculoskeletal stiffness in Valchlor

Expand to all the drugs that have ingredients of mechlorethamine hydrochloride:

Musculoskeletal stiffness and drugs with ingredients of mechlorethamine hydrochloride (14 reports)

Alternative drugs to, pros and cons of Valchlor:

Valchlor (2,463 reports)

Common Valchlor side effects:

Rashes (redness): 435 reports
Itching: 414 reports
Skin discoloration: 199 reports
Dry skin: 123 reports

Browse all side effects of Valchlor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Musculoskeletal stiffness treatments and more:

Musculoskeletal stiffness (87,653 reports)

COVID vaccines that are related to Musculoskeletal stiffness:

Common drugs associated with Musculoskeletal stiffness:

All the drugs that are associated with Musculoskeletal stiffness:

Musculoskeletal stiffness (2,464 drugs)

Common conditions associated with Musculoskeletal stiffness:

All the conditions that are associated with Musculoskeletal stiffness:

Musculoskeletal stiffness (1,848 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mechlorethamine hydrochloride (the active ingredients of Valchlor) and Valchlor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.