Valproic acid and Drug level increased - a phase IV clinical study of FDA data
Summary:
Drug level increased is found among people who take Valproic acid, especially for people who are male, 40-49 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Valproic acid and have Drug level increased. It is created by eHealthMe based on reports of 30,749 people who have side effects when taking Valproic acid from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
30,749 people reported to have side effects when taking Valproic acid.
Among them, 425 people (1.38%) have Drug level increased.
What is Valproic acid?
Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 31,097 Valproic acid users for its effectiveness, alternative drugs and more.
What is Drug level increased?
Drug level increased is found to be associated with 1,420 drugs and 1,072 conditions by eHealthMe.
Number of Valproic acid and Drug level increased reports submitted per year:

Time on Valproic acid when people have Drug level increased *:
Gender of people who have Drug level increased when taking Valproic acid*:
Age of people who have Drug level increased when taking Valproic acid *:
Common drugs people take besides Valproic acid *:
Common side effects people have besides Drug level increased *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Valproic acid and have Drug level increased?
Check whether Drug level increased is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .
Related studies
How severe was Drug level increased and when was it recovered:
Expand to all the drugs that have ingredients of valproic acid:
Alternative drugs to, pros and cons of Valproic acid:
- Valproic acid (31,097 reports)
Common Valproic acid side effects:
- Drug ineffective: 2,811 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1,509 reports
- Depression: 1,471 reports
- Drowsiness: 1,302 reports
- Fever: 1,151 reports
- Thrombocytopenia (decrease of platelets in blood): 1,031 reports
- Fatigue (feeling of tiredness): 1,022 reports
Browse all side effects of Valproic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zDrug level increased treatments and more:
- Drug level increased (16,397 reports)
COVID vaccines that are related to Drug level increased:
- Drug level increased in Moderna COVID Vaccine
- Drug level increased in Pfizer BioNTech Covid Vaccine
- Drug level increased in Johnson and Johnson Covid Vaccine
Common drugs associated with Drug level increased:
- Metformin: 1,196 reports
- Tacrolimus: 1,180 reports
- Prednisone: 872 reports
- Methotrexate: 768 reports
- Clozapine: 713 reports
- Amlodipine: 686 reports
- Omeprazole: 659 reports
- Furosemide: 610 reports
- Prednisolone: 493 reports
- Aspirin: 459 reports
All the drugs that are associated with Drug level increased:
- Drug level increased (1,420 drugs)
Common conditions associated with Drug level increased:
- High blood pressure: 794 reports
- Depression: 600 reports
- Schizophrenia: 562 reports
- Pain: 495 reports
- Epilepsy: 492 reports
- Type 2 diabetes: 474 reports
- Atrial fibrillation/flutter: 421 reports
All the conditions that are associated with Drug level increased:
- Drug level increased (1,072 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on valproic acid (the active ingredients of Valproic acid) and Valproic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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