Valtrex and Enlarged heart - a phase IV clinical study of FDA data
Summary:
Enlarged heart is found among people who take Valtrex, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Valtrex and have Enlarged heart. It is created by eHealthMe based on reports of 32,398 people who have side effects when taking Valtrex from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
32,398 people reported to have side effects when taking Valtrex.
Among them, 115 people (0.35%) have Enlarged heart.
What is Valtrex?
Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 34,253 Valtrex users for its effectiveness, alternative drugs and more.
What is Enlarged heart?
Enlarged heart is found to be associated with 2,154 drugs and 1,502 conditions by eHealthMe.
Number of Valtrex and Enlarged heart reports submitted per year:

Time on Valtrex when people have Enlarged heart *:
Gender of people who have Enlarged heart when taking Valtrex*:
Age of people who have Enlarged heart when taking Valtrex *:
Common drugs people take besides Valtrex *:
Common side effects people have besides Enlarged heart *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Valtrex and have Enlarged heart?
Check whether Enlarged heart is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of Valtrex:
- Valtrex (34,253 reports)
Enlarged heart treatments and more:
- Enlarged heart (18,113 reports)
COVID vaccines that are related to Enlarged heart:
- Enlarged heart in Moderna COVID Vaccine
- Enlarged heart in Pfizer BioNTech Covid Vaccine
- Enlarged heart in Johnson and Johnson Covid Vaccine
How severe was Enlarged heart and when was it recovered:
Expand to all the drugs that have ingredients of valacyclovir hydrochloride:
Common drugs associated with Enlarged heart:
- Accupril: 209 reports
- Acetaminophen: 458 reports
- Acetylsalicylic acid: 239 reports
- Aciphex: 122 reports
- Actonel: 140 reports
- Actos: 296 reports
- Acyclovir: 218 reports
- Adcirca: 135 reports
- Adriamycin pfs: 123 reports
- Advair diskus 100/50: 299 reports
- Advil: 128 reports
- Albuterol: 608 reports
- Aldactone: 375 reports
- Alendronate sodium: 235 reports
- Alkeran: 120 reports
- Allegra: 275 reports
- Allopurinol: 614 reports
- Alprazolam: 435 reports
- Altace: 255 reports
- Amaryl: 153 reports
- Ambien: 684 reports
- Amlodipine: 588 reports
- Amlodipine besylate: 123 reports
- Amoxicillin: 441 reports
- Ancef: 103 reports
- Aranesp: 251 reports
- Aredia: 955 reports
- Aricept: 126 reports
- Arimidex: 177 reports
- Aromasin: 115 reports
- Aspirin: 1,765 reports
- Atenolol: 575 reports
- Ativan: 508 reports
- Atrovent: 209 reports
- Augmentin: 343 reports
- Augmentin '125': 207 reports
- Avandamet: 108 reports
- Avandia: 699 reports
- Avapro: 102 reports
- Avastin: 128 reports
- Avelox: 138 reports
- Avonex: 213 reports
- Azithromycin: 128 reports
- Baclofen: 159 reports
- Bactrim: 218 reports
- Benadryl: 350 reports
- Benicar: 110 reports
- Bextra: 148 reports
- Biaxin: 145 reports
- Calcium: 150 reports
- Captopril: 143 reports
- Cardizem: 287 reports
- Carvedilol: 541 reports
- Celebrex: 637 reports
- Celexa: 324 reports
- Centrum: 132 reports
- Cephalexin: 236 reports
- Chlorhexidine gluconate: 199 reports
- Cipro: 178 reports
- Citalopram hydrobromide: 124 reports
- Claritin: 212 reports
- Cleocin: 108 reports
- Clonazepam: 263 reports
- Clonidine: 254 reports
- Clozapine: 133 reports
- Clozaril: 131 reports
- Colace: 316 reports
- Combivent: 186 reports
- Coreg: 567 reports
- Coumadin: 942 reports
- Cozaar: 303 reports
- Crestor: 255 reports
- Cyclophosphamide: 217 reports
- Cyclosporine: 127 reports
- Cymbalta: 307 reports
- Cytoxan: 172 reports
- Decadron: 438 reports
- Demadex: 103 reports
- Demerol: 111 reports
- Depakote: 101 reports
- Detrol: 147 reports
- Dexamethasone: 575 reports
- Diazepam: 320 reports
- Diflucan: 189 reports
- Digoxin: 1,289 reports
- Dilaudid: 329 reports
- Diovan: 496 reports
- Diphen: 145 reports
- Doxycycline: 188 reports
- Duoneb: 105 reports
- Duragesic-100: 187 reports
- Effexor: 464 reports
- Effexor xr: 146 reports
- Elavil: 208 reports
- Enalapril maleate: 268 reports
- Enbrel: 215 reports
- Entresto: 194 reports
- Exjade: 109 reports
- Famotidine: 152 reports
- Faslodex: 184 reports
- Femara: 225 reports
- Fentanyl: 373 reports
- Fish oil: 138 reports
- Flagyl: 205 reports
- Flexeril: 215 reports
- Flomax: 241 reports
- Flonase: 271 reports
- Flovent: 123 reports
- Fluconazole: 229 reports
- Fluorouracil: 115 reports
- Fluoxetine: 184 reports
- Folic acid: 543 reports
- Fosamax: 799 reports
- Furosemide: 1,590 reports
- Gabapentin: 461 reports
- Glipizide: 181 reports
- Glucophage: 362 reports
- Glucotrol: 208 reports
- Glyburide: 197 reports
- Heparin: 424 reports
- Herceptin: 123 reports
- Humalog: 168 reports
- Humira: 511 reports
- Hydrochlorothiazide: 714 reports
- Hydrocodone bitartrate and acetaminophen: 143 reports
- Hydrocortisone: 133 reports
- Hydroxyzine: 146 reports
- Hyzaar: 126 reports
- Ibu: 515 reports
- Ibuprofen: 515 reports
- Imdur: 157 reports
- Imodium: 111 reports
- Januvia: 152 reports
- Keflex: 225 reports
- Keppra: 113 reports
- Klonopin: 210 reports
- Klor-con: 281 reports
- Kytril: 158 reports
- Lactulose: 193 reports
- Lanoxin: 291 reports
- Lansoprazole: 174 reports
- Lantus: 329 reports
- Lasix: 2,050 reports
- Letairis: 101 reports
- Levaquin: 674 reports
- Levothyroxine sodium: 223 reports
- Levoxyl: 105 reports
- Lexapro: 400 reports
- Lidoderm: 113 reports
- Lipitor: 1,015 reports
- Lisinopril: 989 reports
- Lomotil: 108 reports
- Lopid: 112 reports
- Lopressor: 324 reports
- Lopurin: 626 reports
- Loraz: 498 reports
- Lorazepam: 416 reports
- Lortab: 322 reports
- Losartan: 239 reports
- Lotensin: 111 reports
- Lotrel: 112 reports
- Lovastatin: 129 reports
- Lovenox: 309 reports
- Lyrica: 304 reports
- Magnesium: 280 reports
- Meclizine: 106 reports
- Meloxicam: 104 reports
- Melphalan hydrochloride: 110 reports
- Metformin: 696 reports
- Methotrexate: 486 reports
- Metoclopramide: 228 reports
- Metolazone: 169 reports
- Metoprolol succinate: 147 reports
- Metoprolol tartrate: 326 reports
- Metronidazole: 161 reports
- Miralax: 199 reports
- Mirtazapine: 137 reports
- Mobic: 102 reports
- Morphine: 561 reports
- Morphine sulfate: 206 reports
- Motrin: 250 reports
- Ms contin: 155 reports
- Mucinex: 137 reports
- Multivitamin: 121 reports
- Naprosyn: 108 reports
- Naproxen: 203 reports
- Nasonex: 152 reports
- Neurontin: 658 reports
- Nexium: 622 reports
- Nifedipine: 175 reports
- Nitroglycerin: 568 reports
- Norco: 133 reports
- Norvasc: 673 reports
- Novolog: 184 reports
- Nuvaring: 112 reports
- Nystatin: 245 reports
- Omeprazole: 595 reports
- Ondansetron: 254 reports
- Opsumit: 190 reports
- Oxycodone: 515 reports
- Oxycontin: 742 reports
- Pantoprazole: 338 reports
- Paracetamol: 143 reports
- Paroxetine: 258 reports
- Paxil: 907 reports
- Paxil cr: 192 reports
- Pepcid: 288 reports
- Percocet: 451 reports
- Peridex: 145 reports
- Phenergan: 365 reports
- Phentermine: 232 reports
- Plavix: 613 reports
- Pravachol: 122 reports
- Prednisolone: 352 reports
- Prednisone: 1,701 reports
- Premarin: 343 reports
- Prempro: 112 reports
- Prevacid: 512 reports
- Prilosec: 829 reports
- Prinivil: 182 reports
- Procardia: 133 reports
- Profen: 524 reports
- Protonix: 714 reports
- Prozac: 443 reports
- Ramipril: 257 reports
- Ranitidine: 223 reports
- Reglan: 366 reports
- Remeron: 120 reports
- Remicade: 146 reports
- Restoril: 183 reports
- Revlimid: 315 reports
- Risperdal: 146 reports
- Rocephin: 178 reports
- Sandostatin: 198 reports
- Sandostatin lar: 168 reports
- Seroquel: 247 reports
- Sertraline: 292 reports
- Simvastatin: 592 reports
- Singulair: 327 reports
- Skelaxin: 111 reports
- Solu-medrol: 140 reports
- Soma: 186 reports
- Spiriva: 216 reports
- Spironolactone: 603 reports
- Symbicort: 127 reports
- Synthroid: 669 reports
- Tamoxifen citrate: 108 reports
- Taxol: 149 reports
- Taxotere: 174 reports
- Temaz: 220 reports
- Temazepam: 216 reports
- Tenormin: 180 reports
- Toprol-xl: 359 reports
- Torsemide: 133 reports
- Tracleer: 183 reports
- Tramadol: 355 reports
- Tricor: 123 reports
- Tylenol: 863 reports
- Tylenol w/ codeine: 118 reports
- Ultram: 221 reports
- Valium: 190 reports
- Valsartan: 164 reports
- Valtrex: 115 reports
- Vasotec: 183 reports
- Velcade: 317 reports
- Ventolin: 114 reports
- Versed: 158 reports
- Viagra: 109 reports
- Vicodin: 571 reports
- Vioxx: 1,658 reports
- Vitamin d: 170 reports
- Vitamins: 636 reports
- Voltaren: 129 reports
- Vytorin: 110 reports
- Warfarin sodium: 477 reports
- Wellbutrin: 287 reports
- Xanax: 537 reports
- Xarelto: 128 reports
- Xeloda: 126 reports
- Zantac: 355 reports
- Zaroxolyn: 115 reports
- Zestril: 229 reports
- Zide: 623 reports
- Zithromax: 253 reports
- Zocor: 483 reports
- Zofran: 818 reports
- Zofran odt: 103 reports
- Zoloft: 922 reports
- Zolpidem: 253 reports
- Zometa: 1,425 reports
- Zosyn: 103 reports
- Zyprexa: 226 reports
- Zyrtec: 290 reports
All the drugs that are associated with Enlarged heart:
- Enlarged heart (2,154 drugs)
Common conditions associated with Enlarged heart:
- Abnormal heart rhythms: 126 reports
- Acid reflux: 213 reports
- Acromegaly: 141 reports
- Acupuncture and pain: 570 reports
- A-fib: 373 reports
- Antidepressant therapy: 1,064 reports
- Anxiety: 481 reports
- Anxiety and stress: 481 reports
- Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 481 reports
- Anxiolytic therapy: 483 reports
- Apprehension: 481 reports
- Arrhythmia: 129 reports
- Arrhythmias: 126 reports
- Arthralgia: 128 reports
- Arthritis: 347 reports
- Arthritis - osteoarthritis: 140 reports
- Asthma: 367 reports
- Atrial fibrillation: 373 reports
- Atrial fibrillation/flutter: 368 reports
- Atrial flutter: 357 reports
- Auricular fibrillation: 373 reports
- Back pain: 238 reports
- Birth control: 135 reports
- Blood cholesterol abnormal: 334 reports
- Blood cholesterol increased: 334 reports
- Blood pressure abnormal: 182 reports
- Blood pressure - high: 1,243 reports
- Blood pressure increased: 1,243 reports
- Blood triglycerides abnormal: 340 reports
- Blood triglycerides increased: 334 reports
- Bone and joint pain: 128 reports
- Breast cancer: 274 reports
- Breast cancer metastatic: 152 reports
- Cancer - breast: 274 reports
- Cannot sleep: 192 reports
- Cardiac disorder: 220 reports
- Cardiac failure: 214 reports
- Cardiac failure congestive: 104 reports
- Chronic asthma: 342 reports
- Chronic myeloid leukaemia: 183 reports
- Contraception: 137 reports
- Depression: 1,064 reports
- Diabetes: 704 reports
- Diabetes mellitus: 724 reports
- Diabetes mellitus non-insulin-dependent: 314 reports
- Djd: 140 reports
- Dm: 704 reports
- Dyslipidemia: 334 reports
- Dysrhythmias: 126 reports
- Exercise-induced asthma: 342 reports
- Family planning and contraception: 135 reports
- Foetal exposure during pregnancy: 366 reports
- Gastroesophageal reflux disease: 216 reports
- Gastrooesophageal reflux disease: 214 reports
- Gerd: 214 reports
- Hbp: 1,244 reports
- Headache: 101 reports
- Heartburn: 213 reports
- Heart fibrillation: 368 reports
- High blood cholesterol: 340 reports
- High blood cholesterol and triglycerides: 359 reports
- High blood pressure: 1,243 reports
- High cholesterol: 334 reports
- Hiv: 152 reports
- Hiv antibody positive: 147 reports
- Hiv infection: 157 reports
- Hiv test: 147 reports
- Human immunodeficiency virus infection: 147 reports
- Hypercholesterolaemia: 334 reports
- Hypercholesterolaemia aggravated: 340 reports
- Hypercholesterolemia: 340 reports
- Hyperlipidaemia: 114 reports
- Hyperlipidemia: 359 reports
- Hyperlipoproteinemia: 359 reports
- Hypertension: 1,243 reports
- Hypothyroidism: 159 reports
- Ill-defined disorder: 106 reports
- Inability to sleep: 195 reports
- Insomnia: 193 reports
- Insomnia concerns: 192 reports
- Insomnolence: 193 reports
- Jitters: 481 reports
- Joint pain: 129 reports
- Ldl/hdl ratio increased: 340 reports
- Lipid disorders: 353 reports
- Lipid profile: 267 reports
- Lower cholesterol: 256 reports
- Low thyroid: 154 reports
- Metastases to bone: 210 reports
- Ms: 378 reports
- Multiple myeloma: 724 reports
- Multiple sclerosis: 369 reports
- Myxedema: 159 reports
- Nausea: 126 reports
- Neoplasm malignant: 106 reports
- Niddm: 410 reports
- Nonspecific back pain: 247 reports
- Oa: 140 reports
- Osteoarthritis: 140 reports
- Osteoarthrosis: 140 reports
- Osteopenia: 162 reports
- Osteoporosis: 697 reports
- Pain: 730 reports
- Pain - joints: 126 reports
- Pain management: 699 reports
- Parkinson's disease: 119 reports
- Plasma cell myeloma: 717 reports
- Pregnancy: 135 reports
- Preventive health care: 185 reports
- Primary pulmonary hypertension: 445 reports
- Psoriasis: 190 reports
- Psoriatic arthropathy: 129 reports
- Pulmonary arterial hypertension: 445 reports
- Pulmonary hypertension: 179 reports
- Ra: 673 reports
- Rheumatoid arthritis: 673 reports
- Schizophrenia: 234 reports
- Sleep disorder: 143 reports
- Sleep disorders: 143 reports
- Sleep disorder therapy: 141 reports
- Sleep - too much: 143 reports
- Stress: 483 reports
- Stress and anxiety: 481 reports
- Tachycardia: 126 reports
- Tension: 481 reports
- Type 2 diabetes: 379 reports
- Type 2 diabetes mellitus: 379 reports
- Under active thyroids: 154 reports
- Wakefulness: 193 reports
All the conditions that are associated with Enlarged heart:
- Enlarged heart (1,502 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on valacyclovir hydrochloride (the active ingredients of Valtrex) and Valtrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Hepatic Function Abnormal and Thrombocytopenia - 10 seconds ago
- Coenzyme Q10 and Breath Sounds - 21 seconds ago
- Cefdinir vs. Ciprofloxacin - 35 seconds ago
- Alimta and Progressive Multifocal Leukoencephalopathy - 35 seconds ago
- Bystolic and Yasmin drug interaction - 40 seconds ago