Ventolin and Oesophageal perforation - a phase IV clinical study of FDA data


Oesophageal perforation is reported only by a few people who take Ventolin.

The phase IV clinical study analyzes which people take Ventolin and have Oesophageal perforation. It is created by eHealthMe based on reports of 50,623 people who have side effects while taking Ventolin from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 08, 2022

50,623 people reported to have side effects when taking Ventolin.
Among them, 4 people (0.01%) have Oesophageal perforation.

What is Ventolin?

Ventolin has active ingredients of albuterol. It is often used in asthma. eHealthMe is studying from 51,686 Ventolin users for its effectiveness, alternative drugs and more.

What is Oesophageal perforation?

Oesophageal perforation (hole in oesophagus) is found to be associated with 373 drugs and 231 conditions by eHealthMe.

Number of Ventolin and Oesophageal perforation reports submitted per year:

Could Ventolin cause Oesophageal perforation?

Gender of people who have Oesophageal perforation when taking Ventolin *:

  • female: 50 %
  • male: 50 %

Age of people who have Oesophageal perforation when taking Ventolin *:

  • 0-1: 0.0 %
  • 2-9: 25 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 75 %

Common drugs people take besides Ventolin *:

  1. Vibra-Tabs: 1 person, 25.00%
  2. Symbicort: 1 person, 25.00%
  3. Sandostatin Lar: 1 person, 25.00%
  4. Epipen Jr.: 1 person, 25.00%
  5. Cortef: 1 person, 25.00%
  6. Alvesco: 1 person, 25.00%
  7. Advair Hfa: 1 person, 25.00%

Common side effects people have besides Oesophageal perforation *:

  1. Weight Decreased: 1 person, 25.00%
  2. Urination - Excessive At Night: 1 person, 25.00%
  3. Breathing Difficulty: 1 person, 25.00%
  4. Cardiac Disorder: 1 person, 25.00%
  5. Chest Pain: 1 person, 25.00%
  6. Fatigue (feeling of tiredness): 1 person, 25.00%
  7. Gallstones (stone formation by bile component): 1 person, 25.00%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 25.00%
  9. Headache (pain in head): 1 person, 25.00%
  10. Injection Site Injury: 1 person, 25.00%

Common conditions people have *:

  1. Food Allergy: 1 person, 25.00%
  2. Breathing Difficulty: 1 person, 25.00%
  3. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ventolin and have Oesophageal perforation?

Check whether Oesophageal perforation is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Oesophageal perforation and when was it recovered:

Expand to all the drugs that have ingredients of albuterol:

Alternative drugs to, pros and cons of Ventolin:

Common Ventolin side effects:

Browse all side effects of Ventolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Oesophageal perforation treatments and more:

COVID vaccines that are related to Oesophageal perforation:

All the drugs that are associated with Oesophageal perforation:

All the conditions that are associated with Oesophageal perforation:

How the study uses the data?

The study uses data from the FDA. It is based on albuterol (the active ingredients of Ventolin) and Ventolin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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