Vfend and Polyneuropathy - a phase IV clinical study of FDA data


Polyneuropathy is found among people who take Vfend, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Vfend and have Polyneuropathy. It is created by eHealthMe based on reports of 11,592 people who have side effects when taking Vfend from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 27, 2023

11,592 people reported to have side effects when taking Vfend.
Among them, 35 people (0.3%) have Polyneuropathy.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 11,639 Vfend users for its effectiveness, alternative drugs and more.

What is Polyneuropathy?

Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously) is found to be associated with 1,357 drugs and 886 conditions by eHealthMe.

Number of Vfend and Polyneuropathy reports submitted per year:

Could Vfend cause Polyneuropathy?

Time on Vfend when people have Polyneuropathy *:

  • < 1 month: 45.45 %
  • 1 - 6 months: 54.55 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Polyneuropathy when taking Vfend *:

  • female: 65.71 %
  • male: 34.29 %

Age of people who have Polyneuropathy when taking Vfend *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.41 %
  • 30-39: 3.7 %
  • 40-49: 11.11 %
  • 50-59: 48.15 %
  • 60+: 29.63 %

Common drugs people take besides Vfend *:

  1. Dexamethasone: 14 people, 40.00%
  2. Zyvox: 13 people, 37.14%
  3. Fluconazole: 13 people, 37.14%
  4. Nystatin: 13 people, 37.14%
  5. Nitrofurantoin: 13 people, 37.14%
  6. Neulasta: 13 people, 37.14%
  7. Lyrica: 13 people, 37.14%
  8. Lidoderm: 13 people, 37.14%
  9. Zometa: 13 people, 37.14%
  10. Hydrochlorothiazide: 13 people, 37.14%

Common side effects people have besides Polyneuropathy *:

  1. Osteoporosis (bones weak and more likely to break): 17 people, 48.57%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 15 people, 42.86%
  3. Pain: 14 people, 40.00%
  4. Fever: 14 people, 40.00%
  5. Weakness: 14 people, 40.00%
  6. Urinary Tract Infection: 13 people, 37.14%
  7. Stress And Anxiety: 13 people, 37.14%
  8. Hydrocephalus (water on the brain): 13 people, 37.14%
  9. Pain In Jaw: 13 people, 37.14%
  10. Disability: 13 people, 37.14%

Common conditions people have *:

  1. Neoplasm Malignant (cancer tumour): 10 people, 28.57%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 17.14%
  3. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 4 people, 11.43%
  4. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 2 people, 5.71%
  5. Fungal Infection: 2 people, 5.71%
  6. Sinusitis Fungal (fungal infection of sinus): 1 person, 2.86%
  7. Peripheral Neuropathy (damage to nerves of the peripheral nervous system): 1 person, 2.86%
  8. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 2.86%
  9. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 1 person, 2.86%
  10. Constipation: 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Vfend and have Polyneuropathy?

Check whether Polyneuropathy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Polyneuropathy and when was it recovered:

Expand to all the drugs that have ingredients of voriconazole:

Alternative drugs to, pros and cons of Vfend:

Common Vfend side effects:

Browse all side effects of Vfend:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Polyneuropathy treatments and more:

COVID vaccines that are related to Polyneuropathy:

Common drugs associated with Polyneuropathy:

All the drugs that are associated with Polyneuropathy:

Common conditions associated with Polyneuropathy:

All the conditions that are associated with Polyneuropathy:

How the study uses the data?

The study uses data from the FDA. It is based on voriconazole (the active ingredients of Vfend) and Vfend (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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