Vimovo and Atrial fibrillation/flutter - a phase IV clinical study of FDA data


Atrial fibrillation/flutter is found among people who take Vimovo, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Vimovo and have Atrial fibrillation/flutter. It is created by eHealthMe based on reports of 9,008 people who have side effects when taking Vimovo from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 24, 2023

9,008 people reported to have side effects when taking Vimovo.
Among them, 16 people (0.18%) have Atrial fibrillation/flutter.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,116 Vimovo users for its effectiveness, alternative drugs and more.

What is Atrial fibrillation/flutter?

Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles) is found to be associated with 3,821 drugs and 3,621 conditions by eHealthMe.

Number of Vimovo and Atrial fibrillation/flutter reports submitted per year:

Could Vimovo cause Atrial fibrillation/flutter?

Time on Vimovo when people have Atrial fibrillation/flutter *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Atrial fibrillation/flutter when taking Vimovo *:

  • female: 81.25 %
  • male: 18.75 %

Age of people who have Atrial fibrillation/flutter when taking Vimovo *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.14 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 28.57 %
  • 60+: 64.29 %

Common drugs people take besides Vimovo *:

  1. Metoprolol Tartrate: 3 people, 18.75%
  2. Lantus: 2 people, 12.50%
  3. Remicade: 2 people, 12.50%
  4. Felodipine: 2 people, 12.50%
  5. Zolpidem Tartrate: 2 people, 12.50%
  6. Lasix: 2 people, 12.50%
  7. Melatonin: 2 people, 12.50%
  8. Paracetamol: 2 people, 12.50%
  9. Crestor: 2 people, 12.50%
  10. Humira: 2 people, 12.50%

Common side effects people have besides Atrial fibrillation/flutter *:

  1. Hyperkalemia (damage to or disease of the kidney): 5 people, 31.25%
  2. Hepatic Function Abnormal: 4 people, 25.00%
  3. Diaphragmalgia (pain in the diaphragm): 3 people, 18.75%
  4. Blood Creatinine Increased: 3 people, 18.75%
  5. Heart Rate Decreased: 3 people, 18.75%
  6. Drowsiness: 2 people, 12.50%
  7. Hypotension (abnormally low blood pressure): 2 people, 12.50%
  8. High Blood Cholesterol: 2 people, 12.50%
  9. Heart Rate Irregular: 2 people, 12.50%
  10. Hyperhidrosis (abnormally increased sweating): 2 people, 12.50%

Common conditions people have *:

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 12.50%
  2. High Blood Pressure: 2 people, 12.50%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 12.50%
  4. Spinal Osteoarthritis (joint cartilage loss in spine): 1 person, 6.25%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.25%
  6. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 6.25%
  7. Joint Pain: 1 person, 6.25%
  8. Indigestion: 1 person, 6.25%
  9. Heart Rate Irregular: 1 person, 6.25%
  10. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Vimovo and have Atrial fibrillation/flutter?

Check whether Atrial fibrillation/flutter is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Atrial fibrillation/flutter and when was it recovered:

Expand to all the drugs that have ingredients of esomeprazole magnesium; naproxen:

Alternative drugs to, pros and cons of Vimovo:

Common Vimovo side effects:

Browse all side effects of Vimovo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Atrial fibrillation/flutter treatments and more:

COVID vaccines that are related to Atrial fibrillation/flutter:

Common drugs associated with Atrial fibrillation/flutter:

All the drugs that are associated with Atrial fibrillation/flutter:

Common conditions associated with Atrial fibrillation/flutter:

All the conditions that are associated with Atrial fibrillation/flutter:

How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium; naproxen (the active ingredients of Vimovo) and Vimovo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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