Vioxx and Chronic fatigue syndrome - a phase IV clinical study of FDA data

Summary:

We study 109,982 people who have side effects when taking Vioxx. Chronic fatigue syndrome is found, especially among people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take Tylenol and have High blood pressure.

The phase IV clinical study analyzes which people take Vioxx and have Chronic fatigue syndrome. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 29, 2023

109,982 people reported to have side effects when taking Vioxx.
Among them, 341 people (0.31%) have Chronic fatigue syndrome.

What is Vioxx?

Vioxx has active ingredients of rofecoxib. It is used in arthritis. Currently, eHealthMe is studying from 110,015 Vioxx users.

What is Chronic fatigue syndrome?

Chronic fatigue syndrome (disorder that causes extreme fatigue) is found to be associated with 868 drugs and 844 conditions by eHealthMe. Currently, we are studying 5,045 people who have Chronic fatigue syndrome.

Number of Vioxx and Chronic fatigue syndrome reports submitted per year:

Could Vioxx cause Chronic fatigue syndrome?

* Approximation only. Some reports may have incomplete information.

Do you take Vioxx and have Chronic fatigue syndrome?

Check whether Chronic fatigue syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Vioxx side effects by duration, gender and age:

Vioxx side effects (110,015 reports)

Chronic fatigue syndrome treatments and more:

Chronic fatigue syndrome (5,045 reports)

Common drugs associated with Chronic fatigue syndrome:

Vioxx: 341 reports
Accutane: 328 reports
Zoloft: 109 reports

All the drugs that are associated with Chronic fatigue syndrome:

Chronic fatigue syndrome (868 drugs)

Common conditions associated with Chronic fatigue syndrome:

Acne: 178 reports
Pain: 125 reports
Depression: 111 reports
High blood pressure: 102 reports

All the conditions that are associated with Chronic fatigue syndrome:

Chronic fatigue syndrome (844 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rofecoxib (the active ingredients of Vioxx) and Vioxx (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.