Vioxx and Congestive cardiomyopathy - a phase IV clinical study of FDA data
Summary:
We study 109,982 people who have side effects when taking Vioxx. Congestive cardiomyopathy is found, especially among people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take Lasix and have Joint pain.
The phase IV clinical study analyzes which people take Vioxx and have Congestive cardiomyopathy. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
What are phase IV trials?
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
109,982 people reported to have side effects when taking Vioxx.
Among them, 302 people (0.27%) have Congestive cardiomyopathy.
What is Vioxx?
Vioxx has active ingredients of rofecoxib. It is used in arthritis. Currently, eHealthMe is studying from 110,014 Vioxx users.
What is Congestive cardiomyopathy?
Congestive cardiomyopathy (weakening of heart muscle) is found to be associated with 1,574 drugs and 954 conditions by eHealthMe. Currently, we are studying 7,929 people who have Congestive cardiomyopathy.
Number of Vioxx and Congestive cardiomyopathy reports submitted per year:

Time on Vioxx when people have Congestive cardiomyopathy *:
Gender of people who have Congestive cardiomyopathy when taking Vioxx*:
Age of people who have Congestive cardiomyopathy when taking Vioxx *:
Common drugs people take besides Vioxx *:
Common side effects people have besides Congestive cardiomyopathy *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Vioxx and have Congestive cardiomyopathy?
Check whether Congestive cardiomyopathy is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Congestive cardiomyopathy and when was it recovered:
Expand to all the drugs that have ingredients of rofecoxib:
Alternative drugs to, pros and cons of Vioxx:
- Vioxx (110,014 reports)
Browse all side effects of Vioxx:
a b c d e f g h i j k l m n o p q r s t u v w x y zCongestive cardiomyopathy treatments and more:
- Congestive cardiomyopathy (7,929 reports)
Common drugs associated with Congestive cardiomyopathy:
- Furosemide: 514 reports
- Avandia: 388 reports
- Aspirin: 370 reports
- Digoxin: 347 reports
- Lasix: 346 reports
- Spironolactone: 302 reports
- Vioxx: 302 reports
- Metformin: 272 reports
- Cyclophosphamide: 253 reports
- Carvedilol: 250 reports
All the drugs that are associated with Congestive cardiomyopathy:
- Congestive cardiomyopathy (1,574 drugs)
Common conditions associated with Congestive cardiomyopathy:
- Diabetes: 358 reports
- Schizophrenia: 287 reports
- High blood pressure: 285 reports
- Depression: 241 reports
- Breast cancer: 207 reports
- Rheumatoid arthritis: 179 reports
All the conditions that are associated with Congestive cardiomyopathy:
- Congestive cardiomyopathy (954 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on rofecoxib (the active ingredients of Vioxx) and Vioxx (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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