Vioxx and Localised osteoarthritis - a phase IV clinical study of FDA data
Summary:
Localised osteoarthritis is found among people who take Vioxx, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months.
The phase IV clinical study analyzes which people take Vioxx and have Localised osteoarthritis. It is created by eHealthMe based on reports of 109,615 people who have side effects when taking Vioxx from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
109,615 people reported to have side effects when taking Vioxx.
Among them, 228 people (0.21%) have Localised osteoarthritis.
What is Vioxx?
Vioxx has active ingredients of rofecoxib. It is often used in arthritis. eHealthMe is studying from 109,647 Vioxx users for its effectiveness, alternative drugs and more.
What is Localised osteoarthritis?
Localised osteoarthritis (infection of joint affects only single joint) is found to be associated with 364 drugs and 109 conditions by eHealthMe.
Number of Vioxx and Localised osteoarthritis reports submitted per year:

Time on Vioxx when people have Localised osteoarthritis *:
Gender of people who have Localised osteoarthritis when taking Vioxx*:
Age of people who have Localised osteoarthritis when taking Vioxx *:
Common drugs people take besides Vioxx *:
Common side effects people have besides Localised osteoarthritis *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Vioxx and have Localised osteoarthritis?
Check whether Localised osteoarthritis is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of Vioxx:
- Vioxx (109,647 reports)
Localised osteoarthritis treatments and more:
- Localised osteoarthritis (1,124 reports)
COVID vaccines that are related to Localised osteoarthritis:
- Localised osteoarthritis in Moderna COVID Vaccine
- Localised osteoarthritis in Pfizer BioNTech Covid Vaccine
- Localised osteoarthritis in Johnson and Johnson Covid Vaccine
How severe was Localised osteoarthritis and when was it recovered:
Expand to all the drugs that have ingredients of rofecoxib:
Common drugs associated with Localised osteoarthritis:
- Vioxx: 228 reports
All the drugs that are associated with Localised osteoarthritis:
- Localised osteoarthritis (364 drugs)
All the conditions that are associated with Localised osteoarthritis:
- Localised osteoarthritis (109 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on rofecoxib (the active ingredients of Vioxx) and Vioxx (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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