Vitamin b6 and Dupuytren's contracture - a phase IV clinical study of FDA data
Summary:
Dupuytren's contracture is found among people who take Vitamin b6, especially for people who are female, 60+ old.
The phase IV clinical study analyzes which people take Vitamin b6 and have Dupuytren's contracture. It is created by eHealthMe based on reports of 13,299 people who have side effects when taking Vitamin b6 from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
13,299 people reported to have side effects when taking Vitamin b6.
Among them, 16 people (0.12%) have Dupuytren's contracture.
What is Vitamin b6?
Vitamin b6 has active ingredients of pyridoxine. It is often used in energy increased. eHealthMe is studying from 12,440 Vitamin b6 users for its effectiveness, alternative drugs and more.
What is Dupuytren's contracture?
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 443 drugs and 205 conditions by eHealthMe.
Number of Vitamin b6 and Dupuytren's contracture reports submitted per year:
Gender of people who have Dupuytren's contracture when taking Vitamin b6 *:
- female: 100 %
- male: 0.0 %
Age of people who have Dupuytren's contracture when taking Vitamin b6 *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
Common drugs people take besides Vitamin b6 *:
- Hydroxyzine: 16 people, 100.00%
- Synthroid: 16 people, 100.00%
- Metformin: 16 people, 100.00%
- Januvia: 15 people, 93.75%
- Demerol: 13 people, 81.25%
- Plaquenil: 10 people, 62.50%
- Crestor: 10 people, 62.50%
- Tylenol: 10 people, 62.50%
- Janumet: 10 people, 62.50%
- Rituxan: 8 people, 50.00%
Common side effects people have besides Dupuytren's contracture *:
- Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 16 people, 100.00%
- Joint Swelling: 16 people, 100.00%
- Infusion Related Reaction: 16 people, 100.00%
- Immunodeficiency Disorders: 16 people, 100.00%
- Hypoaesthesia (reduced sense of touch or sensation): 16 people, 100.00%
- Hyperhidrosis (abnormally increased sweating): 16 people, 100.00%
- Tooth Injury: 16 people, 100.00%
- Drug Ineffective: 16 people, 100.00%
- Dizziness: 16 people, 100.00%
- Cough: 16 people, 100.00%
Common conditions people have *:
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 16 people, 100.00%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 100.00%
- Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 16 people, 100.00%
- Myositis (inflammation of the muscles): 16 people, 100.00%
- Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 16 people, 100.00%
- Vasculitis (inflammation of a blood vessel or blood vessels): 15 people, 93.75%
* Approximation only. Some reports may have incomplete information.
Do you take Vitamin b6 and have Dupuytren's contracture?
Check whether Dupuytren's contracture is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Dupuytren's contracture and when was it recovered:
Expand to all the drugs that have ingredients of pyridoxine:
Alternative drugs to, pros and cons of Vitamin b6:
- Vitamin b6 (12,440 reports)
Common Vitamin b6 side effects:
- Abdominal discomfort: 148 reports
- Abdominal distension: 166 reports
- Abdominal pain: 291 reports
- Abdominal pain upper: 188 reports
- Acute kidney failure: 155 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 120 reports
- Anaemia (lack of blood): 373 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 304 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 121 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 124 reports
- Back pain: 344 reports
- Balance disorder: 152 reports
- Blood creatinine increased: 154 reports
- Blood glucose increased: 210 reports
- Breathing difficulty: 596 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 112 reports
- Cardiac failure congestive: 125 reports
- Cellulitis (infection under the skin): 107 reports
- Chest pain: 358 reports
- Chills (felling of cold): 151 reports
- Chronic kidney disease: 120 reports
- Confusional state: 167 reports
- Constipation: 353 reports
- Cough: 355 reports
- Death: 315 reports
- Dehydration (dryness resulting from the removal of water): 218 reports
- Depression: 339 reports
- Diarrhea: 834 reports
- Disease progression: 119 reports
- Dizziness: 587 reports
- Drowsiness: 255 reports
- Drug hypersensitivity: 116 reports
- Drug ineffective: 740 reports
- Dry mouth: 134 reports
- Dry skin: 106 reports
- Fainting (loss of consciousness and postural tone): 120 reports
- Fall: 518 reports
- Fatigue (feeling of tiredness): 1,160 reports
- Fever: 464 reports
- Gait disturbance: 300 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 120 reports
- Haemoglobin decreased: 306 reports
- Hair loss: 234 reports
- Headache (pain in head): 591 reports
- Head injury: 198 reports
- Heart attack: 108 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 103 reports
- Heart rate increased: 171 reports
- High blood cholesterol: 105 reports
- High blood pressure: 423 reports
- Hyperhidrosis (abnormally increased sweating): 156 reports
- Hypersensitivity: 178 reports
- Hypoaesthesia (reduced sense of touch or sensation): 281 reports
- Hypotension (abnormally low blood pressure): 340 reports
- Indigestion: 174 reports
- Infection: 184 reports
- Infusion related reaction: 110 reports
- Injection site pain: 131 reports
- Insomnia (sleeplessness): 402 reports
- Itching: 294 reports
- Joint pain: 499 reports
- Joint swelling: 183 reports
- Loss of consciousness: 147 reports
- Malaise (a feeling of general discomfort or uneasiness): 382 reports
- Memory loss: 275 reports
- Muscle aches (muscle pain): 193 reports
- Muscle spasms (muscle contraction): 284 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 117 reports
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 108 reports
- Nasopharyngitis (inflammation of the nasopharynx): 210 reports
- Nausea (feeling of having an urge to vomit): 866 reports
- Nausea and vomiting: 523 reports
- Neuropathy peripheral (surface nerve damage): 342 reports
- Oedema peripheral (superficial swelling): 209 reports
- Oropharyngeal pain: 165 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 101 reports
- Pain: 589 reports
- Pain in extremity: 452 reports
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome): 105 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 271 reports
- Peripheral swelling: 235 reports
- Pleural effusion (water on the lungs): 116 reports
- Pneumonia: 467 reports
- Rashes (redness): 543 reports
- Renal impairment (severely reduced kidney function): 111 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 131 reports
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 128 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 163 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 160 reports
- Sinusitis (inflammation of sinus): 168 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 115 reports
- Sleep disorder: 111 reports
- Stress and anxiety: 395 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 107 reports
- Swallowing difficulty: 141 reports
- Swelling: 130 reports
- Taste - impaired: 107 reports
- The flu (the flu is caused by an influenza virus): 157 reports
- Thrombocytopenia (decrease of platelets in blood): 389 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 213 reports
- Urinary tract infection: 369 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 107 reports
- Vision blurred: 162 reports
- Visual impairment: 108 reports
- Weakness: 726 reports
- Weight decreased: 506 reports
- Weight increased: 287 reports
- White blood cell count decreased: 180 reports
- White blood cell count increased: 102 reports
Browse all side effects of Vitamin b6:
a b c d e f g h i j k l m n o p q r s t u v w x y zDupuytren's contracture treatments and more:
- Dupuytren's contracture (2,031 reports)
COVID vaccines that are related to Dupuytren's contracture:
- Dupuytren's contracture in Moderna COVID Vaccine
- Dupuytren's contracture in Pfizer BioNTech Covid Vaccine
- Dupuytren's contracture in Johnson and Johnson Covid Vaccine
Common drugs associated with Dupuytren's contracture:
- Xiaflex: 137 reports
All the drugs that are associated with Dupuytren's contracture:
- Dupuytren's contracture (443 drugs)
All the conditions that are associated with Dupuytren's contracture:
- Dupuytren's contracture (205 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on pyridoxine (the active ingredients of Vitamin b6) and Vitamin b6 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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