Vitamin c and Cerebral ischaemia - a phase IV clinical study of FDA data


Cerebral ischaemia is found among people who take Vitamin c, especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Vitamin c and have Cerebral ischaemia. It is created by eHealthMe based on reports of 69,560 people who have side effects when taking Vitamin c from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

69,560 people reported to have side effects when taking Vitamin c.
Among them, 16 people (0.02%) have Cerebral ischaemia.

What is Vitamin c?

Vitamin c has active ingredients of l-ascorbic acid. It is often used in immune response. eHealthMe is studying from 71,923 Vitamin c users for its effectiveness, alternative drugs and more.

What is Cerebral ischaemia?

Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand) is found to be associated with 1,496 drugs and 861 conditions by eHealthMe.

Number of Vitamin c and Cerebral ischaemia reports submitted per year:

Could Vitamin c cause Cerebral ischaemia?

Time on Vitamin c when people have Cerebral ischaemia *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

Gender of people who have Cerebral ischaemia when taking Vitamin c *:

  • female: 43.75 %
  • male: 56.25 %

Age of people who have Cerebral ischaemia when taking Vitamin c *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 20.0 %
  • 50-59: 26.67 %
  • 60+: 53.33 %

Common drugs people take besides Vitamin c *:

  1. Dilaudid: 4 people, 25.00%
  2. Vitamin D: 4 people, 25.00%
  3. Vitamin D3: 4 people, 25.00%
  4. Pantoprazole: 3 people, 18.75%
  5. Zocor: 3 people, 18.75%
  6. Calcium: 3 people, 18.75%
  7. Vitamin E: 3 people, 18.75%
  8. Neurontin: 3 people, 18.75%
  9. Plavix: 3 people, 18.75%
  10. Celebrex: 3 people, 18.75%

Common side effects people have besides Cerebral ischaemia *:

  1. High Blood Pressure: 6 people, 37.50%
  2. Fall: 5 people, 31.25%
  3. Head Injury: 5 people, 31.25%
  4. Cough: 5 people, 31.25%
  5. Vision Blurred: 4 people, 25.00%
  6. Posterior Reversible Encephalopathy Syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss): 3 people, 18.75%
  7. Pleural Effusion (water on the lungs): 3 people, 18.75%
  8. Pneumonia: 3 people, 18.75%
  9. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 3 people, 18.75%
  10. Pain In Extremity: 3 people, 18.75%

Common conditions people have *:

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
  2. Weight Decreased: 3 people, 18.75%
  3. Acne (skin problems that cause pimples): 3 people, 18.75%
  4. Asthma: 3 people, 18.75%
  5. Back Pain: 3 people, 18.75%
  6. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 12.50%
  7. High Blood Pressure: 2 people, 12.50%
  8. Dry Eyes (lack of adequate tears): 2 people, 12.50%
  9. Indigestion: 2 people, 12.50%
  10. Constipation: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin c and have Cerebral ischaemia?

Check whether Cerebral ischaemia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Cerebral ischaemia and when was it recovered:

Expand to all the drugs that have ingredients of l-ascorbic acid:

Alternative drugs to, pros and cons of Vitamin c:

Common Vitamin c side effects:

Browse all side effects of Vitamin c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Cerebral ischaemia treatments and more:

COVID vaccines that are related to Cerebral ischaemia:

Common drugs associated with Cerebral ischaemia:

All the drugs that are associated with Cerebral ischaemia:

Common conditions associated with Cerebral ischaemia:

All the conditions that are associated with Cerebral ischaemia:

How the study uses the data?

The study uses data from the FDA. It is based on l-ascorbic acid (the active ingredients of Vitamin c) and Vitamin c (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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