Vitamin c and Headache - from FDA reports

Headache is found among people who take Vitamin c, especially for people who are female, 60+ old , have been taking the drug for 2 - 5 years, also take medication Vitamin D, and have Rheumatoid arthritis. This review analyzes which people have Headache with Vitamin c. It is created by eHealthMe based on reports of 23,656 people who have side effects when taking Vitamin c from FDA , and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA since 1977. Our original studies have been referenced on 400+ peer-reviewed medical publications, including: The Lancet, and Mayo Clinic Proceedings.

On Apr, 03, 2018

23,656 people reported to have side effects when taking Vitamin c.
Among them, 1,483 people (6.27%) have Headache

Number of reports submitted per year:

Could Vitamin c cause Headache?

Time on Vitamin c when people have Headache *:

  • < 1 month: 14.29 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 14.29 %
  • 1 - 2 years: 28.57 %
  • 2 - 5 years: 42.86 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Headache when taking Vitamin c *:

  • female: 76.91 %
  • male: 23.09 %

Age of people who have Headache when taking Vitamin c *:

  • 0-1: 0.08 %
  • 2-9: 0.08 %
  • 10-19: 1.24 %
  • 20-29: 3.88 %
  • 30-39: 6.11 %
  • 40-49: 13.12 %
  • 50-59: 27.06 %
  • 60+: 48.43 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 152 people, 10.25%
  • Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 124 people, 8.36%
  • Pain: 104 people, 7.01%
  • High Blood Pressure: 98 people, 6.61%
  • High Blood Cholesterol: 72 people, 4.86%

Top co-used drugs for these people *:

  • Vitamin D: 418 people, 28.19%
  • Vitamin B12: 277 people, 18.68%
  • Calcium: 259 people, 17.46%
  • Vitamin D3: 235 people, 15.85%
  • Fish Oil: 233 people, 15.71%

Top other side effects for these people *:

  • Fatigue (feeling of tiredness): 388 people, 26.16%
  • Nausea (feeling of having an urge to vomit): 383 people, 25.83%
  • Dizziness: 289 people, 19.49%
  • Pain: 217 people, 14.63%
  • Diarrhea: 212 people, 14.30%

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Subscribe to the study: get notified of updates to the study.

Want to find out more about the FDA reports used in the study? You can request them from FDA.

Do you take Vitamin c and have Headache?

Related tests

We suggest these affordable tests for self monitoring. You can order them and receive results on eHealthMe. No doctor referral or insurance necessary.

Related studies

Vitamin c

Vitamin c has active ingredients of l-ascorbic acid. It is often used in vitamin supplementation. (latest outcomes from Vitamin c 24,865 users)


Headache (pain in head) has been reported by people with multiple sclerosis, rheumatoid arthritis, high blood pressure, depression, pain (latest reports from 344,789 Headache patients).

Drugs that are associated with Headache
Headache (4,105 drugs)
Could your condition cause Headache
Headache (4,919 conditions)
Expand the study to include all drugs with the same ingredients
Headache and drugs with ingredients of l-ascorbic acid. (1,483 reports)
Expand the study to include reports from both FDA and eHealthMe
Headache and Vitamin c from FDA and eHealthMe reports (1,483 reports)
Vitamin c side effects
Browse all side effects of Vitamin c
a b c d e f g h i j k l m n o p q r s t u v w x y z

Analysis tools (to study 684 million drug outcomes from FDA)

  • Check symptoms - identify the cause of a symptom: from a drug or from a condition?
  • Check drugs - find out common side effects or drug interactions of my drugs.
  • Compare drugs - compare the side effects and efficacy of multiple drugs side by side.

What would happen?

Predict new side effects and undetected conditions when you take Vitamin c and have Headache

You are not alone. Join our personalized support groups:

Can you answer these questions

More questions for: Vitamin c, Headache

You may be interested in these posts

More posts for: Vitamin c, Headache

Recent updates

General studies
Active Support Groups
Recent Predictions
Personalized studies

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.