Vitamin c and Mydriasis - a phase IV clinical study of FDA data


Mydriasis is found among people who take Vitamin c, especially for people who are female, 50-59 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Vitamin c and have Mydriasis. It is created by eHealthMe based on reports of 69,560 people who have side effects when taking Vitamin c from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 19, 2023

69,560 people reported to have side effects when taking Vitamin c.
Among them, 30 people (0.04%) have Mydriasis.

What is Vitamin c?

Vitamin c has active ingredients of l-ascorbic acid. It is often used in immune response. eHealthMe is studying from 71,976 Vitamin c users for its effectiveness, alternative drugs and more.

What is Mydriasis?

Mydriasis (a dilation of the pupil) is found to be associated with 1,759 drugs and 1,118 conditions by eHealthMe.

Number of Vitamin c and Mydriasis reports submitted per year:

Could Vitamin c cause Mydriasis?

Time on Vitamin c when people have Mydriasis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Mydriasis when taking Vitamin c *:

  • female: 65.52 %
  • male: 34.48 %

Age of people who have Mydriasis when taking Vitamin c *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.7 %
  • 20-29: 18.52 %
  • 30-39: 11.11 %
  • 40-49: 3.7 %
  • 50-59: 44.44 %
  • 60+: 18.52 %

Common drugs people take besides Vitamin c *:

  1. Sertraline: 8 people, 26.67%
  2. Beconase Aq: 7 people, 23.33%
  3. Darunavir: 7 people, 23.33%
  4. Vitamin E: 6 people, 20.00%
  5. Emtricitabine: 6 people, 20.00%
  6. Buscopan: 6 people, 20.00%
  7. Vitamin D: 5 people, 16.67%
  8. Fish Oil: 4 people, 13.33%
  9. Myfortic: 3 people, 10.00%
  10. Cancidas: 3 people, 10.00%

Common side effects people have besides Mydriasis *:

  1. Dizziness: 12 people, 40.00%
  2. Dyskinesia (abnormality or impairment of voluntary movement): 10 people, 33.33%
  3. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 10 people, 33.33%
  4. Confusional State: 10 people, 33.33%
  5. Breathing Difficulty: 10 people, 33.33%
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 9 people, 30.00%
  7. Chest Pain: 9 people, 30.00%
  8. Headache (pain in head): 9 people, 30.00%
  9. Hypoaesthesia (reduced sense of touch or sensation): 9 people, 30.00%
  10. Swallowing Difficulty: 9 people, 30.00%

Common conditions people have *:

  1. Stress And Anxiety: 10 people, 33.33%
  2. Ill-Defined Disorder: 7 people, 23.33%
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 13.33%
  4. Wheezing (a high-pitched whistling sound made while you breath): 3 people, 10.00%
  5. Diarrhea: 3 people, 10.00%
  6. Hypersensitivity: 3 people, 10.00%
  7. High Blood Pressure: 3 people, 10.00%
  8. Haemostasis (stopping of bleeding): 3 people, 10.00%
  9. Drug Level Decreased: 3 people, 10.00%
  10. Cardiac Failure: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin c and have Mydriasis?

Check whether Mydriasis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Mydriasis and when was it recovered:

Expand to all the drugs that have ingredients of l-ascorbic acid:

Alternative drugs to, pros and cons of Vitamin c:

Common Vitamin c side effects:

Browse all side effects of Vitamin c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Mydriasis treatments and more:

COVID vaccines that are related to Mydriasis:

Common drugs associated with Mydriasis:

All the drugs that are associated with Mydriasis:

Common conditions associated with Mydriasis:

All the conditions that are associated with Mydriasis:

How the study uses the data?

The study uses data from the FDA. It is based on l-ascorbic acid (the active ingredients of Vitamin c) and Vitamin c (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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