Vitamin d and Injection site warmth - a phase IV clinical study of FDA data
Summary:
We study 224,762 people who have side effects when taking Vitamin d. Injection site warmth is found, especially among people who are female, 60+ old, also take Humira and have Rheumatoid arthritis.
The phase IV clinical study analyzes which people take Vitamin d and have Injection site warmth. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
224,762 people reported to have side effects when taking Vitamin d.
Among them, 244 people (0.11%) have Injection site warmth.
What is Vitamin d?
Vitamin d has active ingredients of ergocalciferol. It is used in low vitamin d. Currently, eHealthMe is studying from 269,877 Vitamin d users.
What is Injection site warmth?
Injection site warmth is found to be associated with 1,066 drugs and 685 conditions by eHealthMe. Currently, we are studying 19,646 people who have Injection site warmth.
Number of Vitamin d and Injection site warmth reports submitted per year:

Gender of people who have Injection site warmth when taking Vitamin d*:
Age of people who have Injection site warmth when taking Vitamin d *:
Common drugs people take besides Vitamin d *:
Common side effects people have besides Injection site warmth *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Vitamin d and have Injection site warmth?
Check whether Injection site warmth is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
Related studies
Vitamin d side effects by duration, gender and age:
- Vitamin d side effects (269,877 reports)
Injection site warmth treatments and more:
- Injection site warmth (19,646 reports)
Common drugs associated with Injection site warmth:
- Enbrel: 10,782 reports
- Humira: 2,623 reports
- Methotrexate: 1,545 reports
- Prednisone: 570 reports
- Taltz: 397 reports
- Folic acid: 393 reports
- Synthroid: 296 reports
- Makena: 294 reports
- Metformin: 248 reports
- Vitamin d: 244 reports
All the drugs that are associated with Injection site warmth:
- Injection site warmth (1,066 drugs)
Common conditions associated with Injection site warmth:
- Rheumatoid arthritis: 6,942 reports
- Psoriasis: 2,455 reports
- Ankylosing spondylitis: 913 reports
- Multiple sclerosis: 746 reports
- Crohn's disease: 648 reports
All the conditions that are associated with Injection site warmth:
- Injection site warmth (685 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ergocalciferol (the active ingredients of Vitamin d) and Vitamin d (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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