Vitamin d and Tumor lysis syndrome - a phase IV clinical study of FDA data

Summary:

Tumor lysis syndrome is found among people who take Vitamin d, especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Vitamin d and have Tumor lysis syndrome. It is created by eHealthMe based on reports of 224,762 people who have side effects when taking Vitamin d from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Aug, 17, 2022

224,762 people reported to have side effects when taking Vitamin d.
Among them, 67 people (0.03%) have Tumor lysis syndrome.


What is Vitamin d?

Vitamin d has active ingredients of ergocalciferol. It is often used in low vitamin d. eHealthMe is studying from 233,797 Vitamin d users for its effectiveness, alternative drugs and more.

What is Tumor lysis syndrome?

Tumor lysis syndrome is found to be associated with 910 drugs and 615 conditions by eHealthMe.

Number of Vitamin d and Tumor lysis syndrome reports submitted per year:

Could Vitamin d cause Tumor lysis syndrome?

Time on Vitamin d when people have Tumor lysis syndrome *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

Gender of people who have Tumor lysis syndrome when taking Vitamin d *:

  • female: 48.48 %
  • male: 51.52 %

Age of people who have Tumor lysis syndrome when taking Vitamin d *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.79 %
  • 20-29: 10.71 %
  • 30-39: 1.79 %
  • 40-49: 0.0 %
  • 50-59: 7.14 %
  • 60+: 78.57 %

Common drugs people take besides Vitamin d *:

  1. Venclexta: 17 people, 25.37%
  2. Calcium: 15 people, 22.39%
  3. Synthroid: 14 people, 20.90%
  4. Imbruvica: 13 people, 19.40%
  5. Vitamin B12: 11 people, 16.42%
  6. Imodium: 8 people, 11.94%
  7. Fish Oil: 8 people, 11.94%
  8. Vitamin C: 7 people, 10.45%
  9. Tylenol: 6 people, 8.96%
  10. Rituxan: 6 people, 8.96%

Common side effects people have besides Tumor lysis syndrome *:

  1. Haemoglobin Decreased: 12 people, 17.91%
  2. High Blood Pressure: 12 people, 17.91%
  3. Constipation: 11 people, 16.42%
  4. Nausea And Vomiting: 10 people, 14.93%
  5. Rashes (redness): 10 people, 14.93%
  6. Nausea (feeling of having an urge to vomit): 10 people, 14.93%
  7. Thrombocytopenia (decrease of platelets in blood): 10 people, 14.93%
  8. Diarrhea: 8 people, 11.94%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 10.45%
  10. Nosebleed (bleeding from nose): 7 people, 10.45%

Common conditions people have *:

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 17 people, 25.37%
  2. High Blood Pressure: 12 people, 17.91%
  3. Diarrhea: 9 people, 13.43%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 8 people, 11.94%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 11.94%
  6. Multiple Myeloma (cancer of the plasma cells): 7 people, 10.45%
  7. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 7 people, 10.45%
  8. Blood Calcium Decreased: 6 people, 8.96%
  9. Thyroid Cancer: 6 people, 8.96%
  10. Pain: 5 people, 7.46%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin d and have Tumor lysis syndrome?

Check whether Tumor lysis syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

How severe was Tumor lysis syndrome and when was it recovered:

Expand to all the drugs that have ingredients of ergocalciferol:

Alternative drugs to, pros and cons of Vitamin d:

Common Vitamin d side effects:

Browse all side effects of Vitamin d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Tumor lysis syndrome treatments and more:

COVID vaccines that are related to Tumor lysis syndrome:

Common drugs associated with Tumor lysis syndrome:

All the drugs that are associated with Tumor lysis syndrome:

Common conditions associated with Tumor lysis syndrome:

All the conditions that are associated with Tumor lysis syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol (the active ingredients of Vitamin d) and Vitamin d (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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