Vitamin d3 and Transfusion reaction - a phase IV clinical study of FDA data
We study 112,976 people who have side effects when taking Vitamin d3. Transfusion reaction is found, especially among people who are male, 60+ old, have been taking the drug for 5 - 10 years, also take Jakafi and have Primary myelofibrosis.
The phase IV clinical study analyzes which people take Vitamin d3 and have Transfusion reaction. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
112,976 people reported to have side effects when taking Vitamin d3.
Among them, 12 people (0.01%) have Transfusion reaction.
What is Vitamin d3?
Vitamin d3 has active ingredients of ergocalciferol. It is used in mineral supplementation. Currently, eHealthMe is studying from 115,513 Vitamin d3 users.
What is Transfusion reaction?
Transfusion reaction (a serious problem that occurs after a patient receives a transfusion of blood) is found to be associated with 643 drugs and 368 conditions by eHealthMe. Currently, we are studying 1,449 people who have Transfusion reaction.
Number of Vitamin d3 and Transfusion reaction reports submitted per year:
Time on Vitamin d3 when people have Transfusion reaction *:
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 100 %
- 10+ years: 0.0 %
Gender of people who have Transfusion reaction when taking Vitamin d3 *:
- female: 28.57 %
- male: 71.43 %
Age of people who have Transfusion reaction when taking Vitamin d3 *:
- 0-1: 0.0 %
- 2-9: 20 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 40 %
- 60+: 40 %
Common drugs people take besides Vitamin d3 *:
- Vitamin B12: 6 people, 50.00%
- Jakafi: 6 people, 50.00%
- Tylenol: 5 people, 41.67%
- Zithromax: 4 people, 33.33%
- Vitamin C: 4 people, 33.33%
- Vitamin D2: 4 people, 33.33%
- Melatonin: 3 people, 25.00%
- Oxycodone: 3 people, 25.00%
- Colace: 3 people, 25.00%
- Hydrocodone Bitartrate And Acetaminophen: 3 people, 25.00%
Common side effects people have besides Transfusion reaction *:
- Pain: 9 people, 75.00%
- Anaemia (lack of blood): 6 people, 50.00%
- Fatigue (feeling of tiredness): 6 people, 50.00%
- Weakness: 5 people, 41.67%
- Insomnia (sleeplessness): 4 people, 33.33%
- Paleness (unusual lightness of skin colour): 4 people, 33.33%
- Abdominal Pain: 4 people, 33.33%
- Abdominal Tenderness: 4 people, 33.33%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 33.33%
- Blood Count Abnormal: 4 people, 33.33%
Common conditions people have *:
- Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 50.00%
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 33.33%
- Pain: 4 people, 33.33%
- Nausea (feeling of having an urge to vomit): 4 people, 33.33%
- Constipation: 3 people, 25.00%
- Stress And Anxiety: 1 person, 8.33%
- Gastric Ulcer (stomach ulcer): 1 person, 8.33%
- Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 8.33%
- Cardiac Disorder: 1 person, 8.33%
- Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Vitamin d3 and have Transfusion reaction?Check whether Transfusion reaction is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
Vitamin d3 side effects by duration, gender and age:
- Vitamin d3 side effects (115,513 reports)
Transfusion reaction treatments and more:
- Transfusion reaction (1,449 reports)
All the drugs that are associated with Transfusion reaction:
- Transfusion reaction (643 drugs)
All the conditions that are associated with Transfusion reaction:
- Transfusion reaction (368 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ergocalciferol (the active ingredients of Vitamin d3) and Vitamin d3 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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