Voltaren and Peptic ulcer haemorrhage - a phase IV clinical study of FDA data


Peptic ulcer haemorrhage is found among people who take Voltaren, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Voltaren and have Peptic ulcer haemorrhage. It is created by eHealthMe based on reports of 69,453 people who have side effects when taking Voltaren from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 17, 2022

69,453 people reported to have side effects when taking Voltaren.
Among them, 13 people (0.02%) have Peptic ulcer haemorrhage.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 61,587 Voltaren users for its effectiveness, alternative drugs and more.

What is Peptic ulcer haemorrhage?

Peptic ulcer haemorrhage (peptic ulcer bleeding) is found to be associated with 423 drugs and 195 conditions by eHealthMe.

Number of Voltaren and Peptic ulcer haemorrhage reports submitted per year:

Could Voltaren cause Peptic ulcer haemorrhage?

Time on Voltaren when people have Peptic ulcer haemorrhage *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Peptic ulcer haemorrhage when taking Voltaren *:

  • female: 84.62 %
  • male: 15.38 %

Age of people who have Peptic ulcer haemorrhage when taking Voltaren *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Voltaren *:

  1. Esomeprazole Magnesium: 4 people, 30.77%
  2. Warfarin Sodium: 2 people, 15.38%
  3. Plavix: 2 people, 15.38%
  4. Aldactone: 2 people, 15.38%
  5. Norvasc: 1 person, 7.69%
  6. Nexium: 1 person, 7.69%
  7. Nexavar: 1 person, 7.69%
  8. Lasix: 1 person, 7.69%
  9. Furosemide: 1 person, 7.69%
  10. Clopidogrel: 1 person, 7.69%

Common side effects people have besides Peptic ulcer haemorrhage *:

  1. Weakness: 5 people, 38.46%
  2. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 5 people, 38.46%
  3. Melaena (the passage of black, tarry stools): 5 people, 38.46%
  4. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 4 people, 30.77%
  5. Blood Glucose Increased: 4 people, 30.77%
  6. Blood Urea Increased: 4 people, 30.77%
  7. C-Reactive Protein Increased: 4 people, 30.77%
  8. Confusional State: 4 people, 30.77%
  9. Fever: 4 people, 30.77%
  10. Haematemesis (vomiting of blood): 4 people, 30.77%

Common conditions people have *:

  1. Hip Fracture: 2 people, 15.38%
  2. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 15.38%
  3. Cardiac Failure: 2 people, 15.38%
  4. Spondylosis (a defect of a vertebra): 1 person, 7.69%
  5. Hepatic Neoplasm Malignant (liver cancer): 1 person, 7.69%
  6. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Voltaren and have Peptic ulcer haemorrhage?

Check whether Peptic ulcer haemorrhage is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Peptic ulcer haemorrhage and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac sodium:

Alternative drugs to, pros and cons of Voltaren:

Common Voltaren side effects:

Browse all side effects of Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Peptic ulcer haemorrhage treatments and more:

COVID vaccines that are related to Peptic ulcer haemorrhage:

Common drugs associated with Peptic ulcer haemorrhage:

All the drugs that are associated with Peptic ulcer haemorrhage:

Common conditions associated with Peptic ulcer haemorrhage:

All the conditions that are associated with Peptic ulcer haemorrhage:

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium (the active ingredients of Voltaren) and Voltaren (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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