Voriconazole and Cheilitis - a phase IV clinical study of FDA data
Summary:
Cheilitis is found among people who take Voriconazole, especially for people who are male, 2-9 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Voriconazole and have Cheilitis. It is created by eHealthMe based on reports of 17,726 people who have side effects when taking Voriconazole from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
On Dec, 08, 2022
17,726 people reported to have side effects when taking Voriconazole.
Among them, 38 people (0.21%) have Cheilitis.
What is Voriconazole?
Voriconazole has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 17,764 Voriconazole users for its effectiveness, alternative drugs and more.
What is Cheilitis?
Cheilitis (infection of lips) is found to be associated with 1,285 drugs and 854 conditions by eHealthMe.
Number of Voriconazole and Cheilitis reports submitted per year:
Time on Voriconazole when people have Cheilitis *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Cheilitis when taking Voriconazole *:
- female: 15.79 %
- male: 84.21 %
Age of people who have Cheilitis when taking Voriconazole *:
- 0-1: 0.0 %
- 2-9: 50.0 %
- 10-19: 41.67 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 2.78 %
- 60+: 5.56 %
Common drugs people take besides Voriconazole *:
- Methotrexate: 22 people, 57.89%
- Cytarabine: 6 people, 15.79%
- Heparin: 4 people, 10.53%
- Mitoxantrone: 4 people, 10.53%
- Zofran: 1 person, 2.63%
- Amlodipine: 1 person, 2.63%
- Cancidas: 1 person, 2.63%
- Cyclosporine: 1 person, 2.63%
- Dilaudid: 1 person, 2.63%
- Duragesic-100: 1 person, 2.63%
Common side effects people have besides Cheilitis *:
- Photosensitivity Reaction: 32 people, 84.21%
- Rashes (redness): 5 people, 13.16%
- Nephropathy Toxic (damage to kidney due to toxins): 5 people, 13.16%
- Sunburn: 4 people, 10.53%
- Rash Macular (small, flat red spots): 4 people, 10.53%
- Drug Level Increased: 3 people, 7.89%
- Actinic Keratosis (skin disease due to sun exposure): 2 people, 5.26%
- Oral Herpes (viral infection of mouth): 2 people, 5.26%
- Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 2 people, 5.26%
- Caecitis (inflammation of the cecum): 1 person, 2.63%
Common conditions people have *:
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 17 people, 44.74%
- Superior Sagittal Sinus Thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain): 5 people, 13.16%
- Abdominal Pain Upper: 5 people, 13.16%
- T-Cell Lymphoma (a blood cell cancer): 4 people, 10.53%
- Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 4 people, 10.53%
- B Precursor Type Acute Leukaemia (lymphoid cancer): 3 people, 7.89%
- T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 1 person, 2.63%
- Rashes (redness): 1 person, 2.63%
- Precursor T-Lymphoblastic Lymphoma/leukaemia (precursor b-cell cancer): 1 person, 2.63%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 2.63%
* Approximation only. Some reports may have incomplete information.
Do you take Voriconazole and have Cheilitis?
Check whether Cheilitis is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Cheilitis and when was it recovered:
Expand to all the drugs that have ingredients of voriconazole:
- Cheilitis and drugs with ingredients of voriconazole (55 reports)
Alternative drugs to, pros and cons of Voriconazole:
- Voriconazole (17,764 reports)
Common Voriconazole side effects:
- Abdominal pain: 251 reports
- Actinic keratosis (skin disease due to sun exposure): 315 reports
- Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant): 118 reports
- Acute kidney failure: 333 reports
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 179 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 603 reports
- Alanine aminotransferase increased: 176 reports
- Anaemia (lack of blood): 418 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 263 reports
- Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 205 reports
- Arrhythmias (irregular heartbeat): 191 reports
- Aspartate aminotransferase increased: 173 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 198 reports
- Back pain: 123 reports
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 126 reports
- Blood alkaline phosphatase increased: 128 reports
- Blood bilirubin increased: 144 reports
- Blood creatinine increased: 190 reports
- Bone marrow failure: 107 reports
- Breathing difficulty: 467 reports
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi): 792 reports
- Cardiac arrest: 170 reports
- Cardiac failure: 133 reports
- Cellulitis (infection under the skin): 158 reports
- Cerebral aspergillosis (pus collection with swelling in brain): 223 reports
- Cerebral haemorrhage (bleeding within the brain): 132 reports
- Chest pain: 160 reports
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 162 reports
- Confusional state: 308 reports
- Constipation: 207 reports
- Cough: 366 reports
- Coughing up blood: 142 reports
- C-reactive protein increased: 146 reports
- Cytomegalovirus infection: 165 reports
- Death: 638 reports
- Dehydration (dryness resulting from the removal of water): 186 reports
- Delirium (wild excitement): 144 reports
- Depression: 117 reports
- Diarrhea: 570 reports
- Disease progression: 251 reports
- Disseminated intravascular coagulation (systemic activation of blood coagulation): 126 reports
- Dizziness: 206 reports
- Drowsiness: 131 reports
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications): 123 reports
- Drug ineffective: 2,635 reports
- Drug intolerance (drug sensitivity): 108 reports
- Drug level below therapeutic: 165 reports
- Drug level decreased: 122 reports
- Drug level increased: 394 reports
- Drug resistance (reduction in effectiveness of a drug): 491 reports
- Electrocardiogram qt prolonged: 199 reports
- Encephalopathy (functioning of the brain is affected by some agent or condition): 123 reports
- Endophthalmitis (inflammation of the internal coats of the eye): 108 reports
- Eye pain: 119 reports
- Fall: 153 reports
- Fatigue (feeling of tiredness): 386 reports
- Febrile neutropenia (fever with reduced white blood cells): 600 reports
- Fever: 1,022 reports
- Fungal infection: 413 reports
- Gait disturbance: 143 reports
- General physical health deterioration (weak health status): 154 reports
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 223 reports
- Haemoglobin decreased: 180 reports
- Hallucinations (sensations that appear real but are created by your mind): 308 reports
- Hallucination, visual (seeing things that aren't there): 205 reports
- Headache (pain in head): 340 reports
- Hepatic enzyme increased: 112 reports
- Hepatotoxicity (chemical-driven liver damage): 378 reports
- High blood pressure: 215 reports
- Hyperkalemia (damage to or disease of the kidney): 161 reports
- Hypoaesthesia (reduced sense of touch or sensation): 122 reports
- Hypokalemia (low potassium): 309 reports
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 130 reports
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 145 reports
- Hypotension (abnormally low blood pressure): 476 reports
- Infection: 276 reports
- Insomnia (sleeplessness): 133 reports
- Joint pain: 172 reports
- Leukopenia (less number of white blood cells in blood): 146 reports
- Lung disorder (lung disease): 137 reports
- Lung infection: 174 reports
- Malaise (a feeling of general discomfort or uneasiness): 143 reports
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 148 reports
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 131 reports
- Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina): 311 reports
- Multi-organ failure (multisystem organ failure): 157 reports
- Muscle aches (muscle pain): 109 reports
- Nausea (feeling of having an urge to vomit): 523 reports
- Nausea and vomiting: 418 reports
- Nephropathy toxic (damage to kidney due to toxins): 124 reports
- Nervous system disorder (a general class of medical conditions affecting the nervous system): 142 reports
- Neuropathy peripheral (surface nerve damage): 186 reports
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 206 reports
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 109 reports
- Oedema peripheral (superficial swelling): 128 reports
- Pain: 193 reports
- Pain in extremity: 135 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 415 reports
- Pathogen resistance: 197 reports
- Periostitis (inflammation of the periosteum, a layer of connective tissue that surrounds bone): 209 reports
- Photodermatosis (skin disease that is caused by exposure to sunlight): 117 reports
- Photosensitivity reaction: 487 reports
- Pleural effusion (water on the lungs): 262 reports
- Pneumonia: 1,023 reports
- Pneumonia fungal: 111 reports
- Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 123 reports
- Rashes (redness): 491 reports
- Renal failure acute (rapid kidney dysfunction): 202 reports
- Renal impairment (severely reduced kidney function): 209 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 599 reports
- Respiratory distress (difficulty in breathing): 141 reports
- Scedosporium infection (a filamentous fungus which occasionally causes infections in humans): 138 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 482 reports
- Septic shock (shock due to blood infection): 522 reports
- Speech impairment (adult) (inability to speak (adult)): 110 reports
- Squamous cell carcinoma (a cancer of a kind of epithelial cell): 178 reports
- Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin): 362 reports
- Staphylococcal infection (an infection with staphylococcus bacteria): 143 reports
- Systemic mycosis (fungal infections of the body): 143 reports
- The flu (the flu is caused by an influenza virus): 110 reports
- Thrombocytopenia (decrease of platelets in blood): 671 reports
- Transaminases increased: 147 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 129 reports
- Uveitis (inflammation of the uvea): 109 reports
- Venoocclusive liver disease (small veins in the liver are obstructed): 119 reports
- Vision blurred: 155 reports
- Visual acuity reduced (reduced clearness of vision): 145 reports
- Visual impairment: 251 reports
- Weakness: 391 reports
- Weight decreased: 188 reports
- White blood cell count decreased: 197 reports
Browse all side effects of Voriconazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zCheilitis treatments and more:
- Cheilitis (6,304 reports)
COVID vaccines that are related to Cheilitis:
- Cheilitis in Moderna COVID Vaccine
- Cheilitis in Pfizer BioNTech Covid Vaccine
- Cheilitis in Johnson and Johnson Covid Vaccine
Common drugs associated with Cheilitis:
- Abreva: 153 reports
- Accutane: 732 reports
- Aspirin: 183 reports
- Augmentin: 105 reports
- Bactrim: 134 reports
- Enbrel: 103 reports
- Fosamax: 139 reports
- Humira: 168 reports
- Ibu: 114 reports
- Ibuprofen: 121 reports
- Lamictal: 176 reports
- Lisinopril: 112 reports
- Methotrexate: 246 reports
- Omeprazole: 138 reports
- Prednisone: 234 reports
All the drugs that are associated with Cheilitis:
- Cheilitis (1,285 drugs)
Common conditions associated with Cheilitis:
- Acne: 439 reports
- Antidepressant therapy: 156 reports
- Asthma: 126 reports
- Blood pressure increased: 224 reports
- Depression: 159 reports
- High blood pressure: 224 reports
- Hypertension: 241 reports
- Osteoporosis: 141 reports
- Pain: 140 reports
- Rheumatoid arthritis: 266 reports
All the conditions that are associated with Cheilitis:
- Cheilitis (854 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on voriconazole (the active ingredients of Voriconazole) and Voriconazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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