Voriconazole and Immunosuppressant drug level increased - a phase IV clinical study of FDA data

Summary:

Immunosuppressant drug level increased is found among people who take Voriconazole, especially for people who are male, 40-49 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Voriconazole and have Immunosuppressant drug level increased. It is created by eHealthMe based on reports of 17,726 people who have side effects when taking Voriconazole from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 02, 2022

17,726 people reported to have side effects when taking Voriconazole.
Among them, 96 people (0.54%) have Immunosuppressant drug level increased.


What is Voriconazole?

Voriconazole has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 17,764 Voriconazole users for its effectiveness, alternative drugs and more.

What is Immunosuppressant drug level increased?

Immunosuppressant drug level increased is found to be associated with 566 drugs and 391 conditions by eHealthMe.

Number of Voriconazole and Immunosuppressant drug level increased reports submitted per year:

Could Voriconazole cause Immunosuppressant drug level increased?

Time on Voriconazole when people have Immunosuppressant drug level increased *:

  • < 1 month: 55.56 %
  • 1 - 6 months: 44.44 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Immunosuppressant drug level increased when taking Voriconazole *:

  • female: 22.08 %
  • male: 77.92 %

Age of people who have Immunosuppressant drug level increased when taking Voriconazole *:

  • 0-1: 2.67 %
  • 2-9: 4.0 %
  • 10-19: 10.67 %
  • 20-29: 2.67 %
  • 30-39: 4.0 %
  • 40-49: 38.67 %
  • 50-59: 12.0 %
  • 60+: 25.33 %

Common drugs people take besides Voriconazole *:

  1. Vancomycin: 29 people, 30.21%
  2. Ciclosporin: 17 people, 17.71%
  3. Cellcept: 13 people, 13.54%
  4. Prograf: 9 people, 9.38%
  5. Tacrolimus: 7 people, 7.29%
  6. Prednisone: 6 people, 6.25%
  7. Methotrexate: 6 people, 6.25%
  8. Methylprednisolone: 5 people, 5.21%
  9. Citicoline: 5 people, 5.21%
  10. Amlodipine: 5 people, 5.21%

Common side effects people have besides Immunosuppressant drug level increased *:

  1. Pneumonia: 29 people, 30.21%
  2. Diarrhea: 28 people, 29.17%
  3. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 28 people, 29.17%
  4. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 27 people, 28.12%
  5. Acute Kidney Failure: 26 people, 27.08%
  6. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 25 people, 26.04%
  7. Vasculitis (inflammation of a blood vessel or blood vessels): 25 people, 26.04%
  8. Neurological Symptom (symptoms of nervous system disease): 25 people, 26.04%
  9. Functional Gastrointestinal Disorder (functional problem in separate organs of gastrointestinal system): 25 people, 26.04%
  10. Rash Erythematous (redness of the skin): 25 people, 26.04%

Common conditions people have *:

  1. Psychiatric Symptom: 25 people, 26.04%
  2. Fungal Infection: 9 people, 9.38%
  3. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 8 people, 8.33%
  4. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 6.25%
  5. Immunodeficiency Disorders: 4 people, 4.17%
  6. Transplant Rejection (a transplant material is not worked): 3 people, 3.12%
  7. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 2 people, 2.08%
  8. Fever: 2 people, 2.08%
  9. Lower Respiratory Tract Infection Fungal: 2 people, 2.08%
  10. Pneumonia: 2 people, 2.08%

* Approximation only. Some reports may have incomplete information.

Do you take Voriconazole and have Immunosuppressant drug level increased?

Check whether Immunosuppressant drug level increased is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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Immunosuppressant drug level increased treatments and more:

COVID vaccines that are related to Immunosuppressant drug level increased:

Common drugs associated with Immunosuppressant drug level increased:

All the drugs that are associated with Immunosuppressant drug level increased:

Common conditions associated with Immunosuppressant drug level increased:

All the conditions that are associated with Immunosuppressant drug level increased:

How the study uses the data?

The study uses data from the FDA. It is based on voriconazole (the active ingredients of Voriconazole) and Voriconazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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