Vortioxetine and Acute kidney failure - a phase IV clinical study of FDA data


Acute kidney failure is found among people who take Vortioxetine, especially for people who are female, 20-29 old, have been taking the drug for 1 - 2 years.

The phase IV clinical study analyzes which people take Vortioxetine and have Acute kidney failure. It is created by eHealthMe based on reports of 1,892 people who have side effects when taking Vortioxetine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 21, 2023

1,892 people reported to have side effects when taking Vortioxetine.
Among them, 32 people (1.69%) have Acute kidney failure.

What is Vortioxetine?

Vortioxetine has active ingredients of vortioxetine. eHealthMe is studying from 1,464 Vortioxetine users for its effectiveness, alternative drugs and more.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 3,995 drugs and 3,953 conditions by eHealthMe.

Number of Vortioxetine and Acute kidney failure reports submitted per year:

Could Vortioxetine cause Acute kidney failure?

Time on Vortioxetine when people have Acute kidney failure *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Acute kidney failure when taking Vortioxetine *:

  • female: 93.33 %
  • male: 6.67 %

Age of people who have Acute kidney failure when taking Vortioxetine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 75.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 17.86 %
  • 60+: 7.14 %

Common drugs people take besides Vortioxetine *:

  1. Ondansetron: 24 people, 75.00%
  2. Ozempic: 16 people, 50.00%
  3. Naltrexone: 13 people, 40.62%
  4. Bupropion Hydrochloride: 12 people, 37.50%
  5. Naltrexone Hydrochloride: 10 people, 31.25%
  6. Nexium: 6 people, 18.75%
  7. Prevacid: 5 people, 15.62%
  8. Protonix: 5 people, 15.62%
  9. Dexilant: 4 people, 12.50%
  10. Prilosec: 3 people, 9.38%

Common side effects people have besides Acute kidney failure *:

  1. Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 23 people, 71.88%
  2. Myopathy (a muscular disease in which the muscle fibres do not function): 23 people, 71.88%
  3. Myoglobinuria (presence of myoglobin in the urine): 23 people, 71.88%
  4. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 17 people, 53.12%
  5. Muscle Aches (muscle pain): 14 people, 43.75%
  6. Muscle Spasms (muscle contraction): 14 people, 43.75%
  7. Chills (felling of cold): 14 people, 43.75%
  8. Headache (pain in head): 14 people, 43.75%
  9. Hyperhidrosis (abnormally increased sweating): 14 people, 43.75%
  10. Body Temperature Increased: 14 people, 43.75%

Common conditions people have *:

  1. Weight Loss: 21 people, 65.62%
  2. Nausea (feeling of having an urge to vomit): 12 people, 37.50%
  3. Depression: 6 people, 18.75%
  4. Pain: 6 people, 18.75%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.50%
  6. High Blood Pressure: 4 people, 12.50%
  7. Renal Disorder (kidney disease): 3 people, 9.38%
  8. Indigestion: 3 people, 9.38%
  9. High Blood Cholesterol: 3 people, 9.38%
  10. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Vortioxetine and have Acute kidney failure?

Check whether Acute kidney failure is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Acute kidney failure and when was it recovered:

Expand to all the drugs that have ingredients of vortioxetine:

Alternative drugs to, pros and cons of Vortioxetine:

Common Vortioxetine side effects:

Browse all side effects of Vortioxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Acute kidney failure treatments and more:

COVID vaccines that are related to Acute kidney failure:

Common drugs associated with Acute kidney failure:

All the drugs that are associated with Acute kidney failure:

Common conditions associated with Acute kidney failure:

All the conditions that are associated with Acute kidney failure:

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine (the active ingredients of Vortioxetine) and Vortioxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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