Xalatan and Ear barotrauma - a phase IV clinical study of FDA data


Ear barotrauma is found among people who take Xalatan, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Xalatan and have Ear barotrauma. It is created by eHealthMe based on reports of 24,358 people who have side effects when taking Xalatan from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On May, 01, 2023

24,358 people reported to have side effects when taking Xalatan.
Among them, 11 people (0.05%) have Ear barotrauma.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 24,707 Xalatan users for its effectiveness, alternative drugs and more.

What is Ear barotrauma?

Ear barotrauma (discomfort and possible damage in the ear due to pressure differences between the inside and outside of the eardrum) is found to be associated with 936 drugs and 586 conditions by eHealthMe.

Number of Xalatan and Ear barotrauma reports submitted per year:

Could Xalatan cause Ear barotrauma?

Gender of people who have Ear barotrauma when taking Xalatan *:

  • female: 18.18 %
  • male: 81.82 %

Age of people who have Ear barotrauma when taking Xalatan *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 0.0 %
  • 60+: 90.91 %

Common drugs people take besides Xalatan *:

  1. Tenormin: 11 people, 100.00%
  2. Klonopin: 10 people, 90.91%
  3. Lasix: 10 people, 90.91%
  4. Lisinopril: 10 people, 90.91%
  5. Plavix: 10 people, 90.91%
  6. Coumadin: 10 people, 90.91%
  7. Prilosec: 10 people, 90.91%
  8. Oxycontin: 9 people, 81.82%
  9. Elavil: 9 people, 81.82%
  10. Prednisone: 9 people, 81.82%

Common side effects people have besides Ear barotrauma *:

  1. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 10 people, 90.91%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 90.91%
  3. Depression: 10 people, 90.91%
  4. Joint Pain: 10 people, 90.91%
  5. Cellulitis (infection under the skin): 10 people, 90.91%
  6. Cataract (clouding of the lens inside the eye): 10 people, 90.91%
  7. Cardiac Failure Congestive: 10 people, 90.91%
  8. Stress And Anxiety: 10 people, 90.91%
  9. Back Pain: 10 people, 90.91%
  10. Oedema Peripheral (superficial swelling): 10 people, 90.91%

Common conditions people have *:

  1. Stable Angina (a constant chest pain): 9 people, 81.82%
  2. Multiple Myeloma (cancer of the plasma cells): 9 people, 81.82%
  3. Depression: 9 people, 81.82%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 81.82%
  5. Arrhythmias (irregular heartbeat): 9 people, 81.82%
  6. Pulmonary Congestion (congestion in the lungs): 1 person, 9.09%
  7. Nausea And Vomiting: 1 person, 9.09%
  8. Nausea (feeling of having an urge to vomit): 1 person, 9.09%
  9. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 9.09%
  10. Impaired Gastric Emptying: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Xalatan and have Ear barotrauma?

Check whether Ear barotrauma is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Ear barotrauma and when was it recovered:

Expand to all the drugs that have ingredients of latanoprost:

Alternative drugs to, pros and cons of Xalatan:

Common Xalatan side effects:

Browse all side effects of Xalatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Ear barotrauma treatments and more:

COVID vaccines that are related to Ear barotrauma:

Common drugs associated with Ear barotrauma:

All the drugs that are associated with Ear barotrauma:

Common conditions associated with Ear barotrauma:

All the conditions that are associated with Ear barotrauma:

How the study uses the data?

The study uses data from the FDA. It is based on latanoprost (the active ingredients of Xalatan) and Xalatan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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