Xarelto and Carotid arteriosclerosis - a phase IV clinical study of FDA data


Carotid arteriosclerosis is found among people who take Xarelto, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Xarelto and have Carotid arteriosclerosis. It is created by eHealthMe based on reports of 195,181 people who have side effects when taking Xarelto from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 03, 2022

195,181 people reported to have side effects when taking Xarelto.
Among them, 10 people (0.01%) have Carotid arteriosclerosis.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 197,062 Xarelto users for its effectiveness, alternative drugs and more.

What is Carotid arteriosclerosis?

Carotid arteriosclerosis (plaque deposition in artery) is found to be associated with 537 drugs and 230 conditions by eHealthMe.

Number of Xarelto and Carotid arteriosclerosis reports submitted per year:

Could Xarelto cause Carotid arteriosclerosis?

Time on Xarelto when people have Carotid arteriosclerosis *:

  • < 1 month: 33.33 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Carotid arteriosclerosis when taking Xarelto *:

  • female: 30 %
  • male: 70 %

Age of people who have Carotid arteriosclerosis when taking Xarelto *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 20 %
  • 50-59: 0.0 %
  • 60+: 80 %

Common drugs people take besides Xarelto *:

  1. Plavix: 4 people, 40.00%
  2. Lipitor: 4 people, 40.00%
  3. Coumadin: 4 people, 40.00%
  4. Zonegran: 2 people, 20.00%
  5. Flagyl: 2 people, 20.00%
  6. Miralax: 2 people, 20.00%
  7. Microzide: 2 people, 20.00%
  8. Mevacor: 2 people, 20.00%
  9. Zofran: 2 people, 20.00%
  10. Lortab: 2 people, 20.00%

Common side effects people have besides Carotid arteriosclerosis *:

  1. Drug Ineffective: 5 people, 50.00%
  2. Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 4 people, 40.00%
  3. Atherosclerosis (disorder of the arteries): 4 people, 40.00%
  4. Basal Ganglion Degeneration (loss of brain tissue in the cortex, or outer layer of the brain): 2 people, 20.00%
  5. Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 20.00%
  6. Hemiparesis (weakness on one side of the body): 2 people, 20.00%
  7. Vitamin D Abnormal: 2 people, 20.00%
  8. Heart Disease: 2 people, 20.00%
  9. Headache (pain in head): 2 people, 20.00%
  10. Back Pain: 2 people, 20.00%

Common conditions people have *:

  1. Pain: 3 people, 30.00%
  2. High Blood Cholesterol: 3 people, 30.00%
  3. Constipation: 2 people, 20.00%
  4. Headache (pain in head): 2 people, 20.00%
  5. Chest Pain: 2 people, 20.00%
  6. Insomnia (sleeplessness): 2 people, 20.00%
  7. Carotid Artery Occlusion (artery blockage): 2 people, 20.00%
  8. Nausea (feeling of having an urge to vomit): 2 people, 20.00%
  9. Nausea And Vomiting: 2 people, 20.00%
  10. High Blood Pressure: 2 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Xarelto and have Carotid arteriosclerosis?

Check whether Carotid arteriosclerosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Carotid arteriosclerosis and when was it recovered:

Expand to all the drugs that have ingredients of rivaroxaban:

Alternative drugs to, pros and cons of Xarelto:

Common Xarelto side effects:

Browse all side effects of Xarelto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Carotid arteriosclerosis treatments and more:

COVID vaccines that are related to Carotid arteriosclerosis:

Common drugs associated with Carotid arteriosclerosis:

All the drugs that are associated with Carotid arteriosclerosis:

Common conditions associated with Carotid arteriosclerosis:

All the conditions that are associated with Carotid arteriosclerosis:

How the study uses the data?

The study uses data from the FDA. It is based on rivaroxaban (the active ingredients of Xarelto) and Xarelto (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: