Xeljanz and Headache - a phase IV clinical study of FDA data
Summary:
Headache is found among people who take Xeljanz, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Xeljanz and have Headache. It is created by eHealthMe based on reports of 222,287 people who have side effects when taking Xeljanz from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
222,287 people reported to have side effects when taking Xeljanz.
Among them, 16,267 people (7.32%) have Headache.
What is Xeljanz?
Xeljanz has active ingredients of tofacitinib citrate. It is often used in rheumatoid arthritis. eHealthMe is studying from 192,441 Xeljanz users for its effectiveness, alternative drugs and more.
What is Headache?
Headache (pain in head) is found to be associated with 5,281 drugs and 5,643 conditions by eHealthMe.
Number of Xeljanz and Headache reports submitted per year:

Time on Xeljanz when people have Headache *:
Gender of people who have Headache when taking Xeljanz*:
Age of people who have Headache when taking Xeljanz *:
Common drugs people take besides Xeljanz *:
Common side effects people have besides Headache *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Xeljanz and have Headache?
Check whether Headache is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Headache and when was it recovered:
Expand to all the drugs that have ingredients of tofacitinib citrate:
- Headache and drugs with ingredients of tofacitinib citrate (13,700 reports)
Alternative drugs to, pros and cons of Xeljanz:
- Xeljanz (192,441 reports)
Common Xeljanz side effects:
- Drug ineffective: 48,562 reports
- Pain: 26,984 reports
- Joint pain: 21,086 reports
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 20,971 reports
- Fatigue (feeling of tiredness): 16,775 reports
- Headache (pain in head): 16,267 reports
- Joint swelling: 15,442 reports
- Rashes (redness): 12,562 reports
- Malaise (a feeling of general discomfort or uneasiness): 11,656 reports
Browse all side effects of Xeljanz:
a b c d e f g h i j k l m n o p q r s t u v w x y zHeadache treatments and more:
- Headache (652,226 reports)
COVID vaccines that are related to Headache:
- Headache in Moderna COVID Vaccine
- Headache in Pfizer BioNTech Covid Vaccine
- Headache in Johnson and Johnson Covid Vaccine
Common drugs associated with Headache:
- Prednisone: 29,566 reports
- Humira: 26,867 reports
- Enbrel: 26,565 reports
- Methotrexate: 25,739 reports
- Aspirin: 21,238 reports
- Otezla: 16,774 reports
- Xeljanz: 16,267 reports
- Omeprazole: 15,229 reports
- Vitamin d: 14,927 reports
- Synthroid: 14,633 reports
All the drugs that are associated with Headache:
- Headache (5,281 drugs)
Common conditions associated with Headache:
- Multiple sclerosis: 41,461 reports
- Rheumatoid arthritis: 40,932 reports
- High blood pressure: 23,165 reports
- Primary pulmonary hypertension: 21,717 reports
- Psoriasis: 19,045 reports
- Depression: 18,850 reports
All the conditions that are associated with Headache:
- Headache (5,643 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on tofacitinib citrate (the active ingredients of Xeljanz) and Xeljanz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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