Xeloda and Dry eye syndrome - a phase IV clinical study of FDA data


Dry eye syndrome is found among people who take Xeloda, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Xeloda and have Dry eye syndrome. It is created by eHealthMe based on reports of 44,763 people who have side effects when taking Xeloda from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 30, 2022

44,763 people reported to have side effects when taking Xeloda.
Among them, 18 people (0.04%) have Dry eye syndrome.

What is Xeloda?

Xeloda has active ingredients of capecitabine. It is often used in colon cancer. eHealthMe is studying from 45,113 Xeloda users for its effectiveness, alternative drugs and more.

What is Dry eye syndrome?

Dry eye syndrome is found to be associated with 890 drugs and 622 conditions by eHealthMe.

Number of Xeloda and Dry eye syndrome reports submitted per year:

Could Xeloda cause Dry eye syndrome?

Time on Xeloda when people have Dry eye syndrome *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Dry eye syndrome when taking Xeloda *:

  • female: 88.89 %
  • male: 11.11 %

Age of people who have Dry eye syndrome when taking Xeloda *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 82.35 %
  • 60+: 17.65 %

Common drugs people take besides Xeloda *:

  1. Navelbine: 14 people, 77.78%
  2. Zometa: 14 people, 77.78%
  3. Atenolol: 14 people, 77.78%
  4. Lipitor: 14 people, 77.78%
  5. Arimidex: 14 people, 77.78%
  6. Faslodex: 14 people, 77.78%
  7. Omeprazole: 14 people, 77.78%
  8. Gabapentin: 14 people, 77.78%
  9. Miralax: 12 people, 66.67%
  10. Metronidazole: 12 people, 66.67%

Common side effects people have besides Dry eye syndrome *:

  1. Oedema Peripheral (superficial swelling): 14 people, 77.78%
  2. Pain: 14 people, 77.78%
  3. Pain In Extremity: 14 people, 77.78%
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 14 people, 77.78%
  5. Fever: 14 people, 77.78%
  6. Impaired Healing: 14 people, 77.78%
  7. Stress And Anxiety: 14 people, 77.78%
  8. Weakness: 13 people, 72.22%
  9. Injury: 13 people, 72.22%
  10. Wound Infection Staphylococcal: 12 people, 66.67%

Common conditions people have *:

  1. Hypercalcaemia (elevated calcium (ca+) level in the blood): 12 people, 66.67%

* Approximation only. Some reports may have incomplete information.

Do you take Xeloda and have Dry eye syndrome?

Check whether Dry eye syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Dry eye syndrome and when was it recovered:

Expand to all the drugs that have ingredients of capecitabine:

Alternative drugs to, pros and cons of Xeloda:

Common Xeloda side effects:

Browse all side effects of Xeloda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Dry eye syndrome treatments and more:

COVID vaccines that are related to Dry eye syndrome:

All the drugs that are associated with Dry eye syndrome:

All the conditions that are associated with Dry eye syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on capecitabine (the active ingredients of Xeloda) and Xeloda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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