Xyzal and Tinnitus - a phase IV clinical study of FDA data


Tinnitus is found among people who take Xyzal, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Xyzal and have Tinnitus. It is created by eHealthMe based on reports of 17,000 people who have side effects when taking Xyzal from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 01, 2022

17,000 people reported to have side effects when taking Xyzal.
Among them, 81 people (0.48%) have Tinnitus.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 17,820 Xyzal users for its effectiveness, alternative drugs and more.

What is Tinnitus?

Tinnitus (a ringing in the ears) is found to be associated with 3,224 drugs and 2,772 conditions by eHealthMe.

Number of Xyzal and Tinnitus reports submitted per year:

Could Xyzal cause Tinnitus?

Time on Xyzal when people have Tinnitus *:

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Tinnitus when taking Xyzal *:

  • female: 49.12 %
  • male: 50.88 %

Age of people who have Tinnitus when taking Xyzal *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.44 %
  • 20-29: 0.0 %
  • 30-39: 24.39 %
  • 40-49: 21.95 %
  • 50-59: 2.44 %
  • 60+: 48.78 %

Common drugs people take besides Xyzal *:

  1. Hydrochlorothiazide: 39 people, 48.15%
  2. Glucosamine: 22 people, 27.16%
  3. Levaquin: 22 people, 27.16%
  4. Acetaminophen: 20 people, 24.69%
  5. Lipitor: 20 people, 24.69%
  6. Pregabalin: 20 people, 24.69%
  7. Potassium Iodide: 20 people, 24.69%
  8. Pentoxifylline: 20 people, 24.69%
  9. Cipro: 20 people, 24.69%
  10. Norfloxacin: 20 people, 24.69%

Common side effects people have besides Tinnitus *:

  1. Breathing Difficulty: 43 people, 53.09%
  2. Joint Pain: 36 people, 44.44%
  3. Headache (pain in head): 35 people, 43.21%
  4. Dizziness: 32 people, 39.51%
  5. Nausea (feeling of having an urge to vomit): 30 people, 37.04%
  6. Weakness: 29 people, 35.80%
  7. Back Pain: 29 people, 35.80%
  8. Nausea And Vomiting: 28 people, 34.57%
  9. Abdominal Pain Upper: 28 people, 34.57%
  10. Cough: 27 people, 33.33%

Common conditions people have *:

  1. High Blood Pressure: 16 people, 19.75%
  2. Asthma: 13 people, 16.05%
  3. Hypersensitivity: 11 people, 13.58%
  4. Metastasis (spreadable cancer to other organ from origin): 8 people, 9.88%
  5. Vaginal Bleeding: 6 people, 7.41%
  6. Cyst (a closed sac): 6 people, 7.41%
  7. Dysmenorrhea (painful menstruation): 6 people, 7.41%
  8. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 6 people, 7.41%
  9. Heavy Or Prolong Menstrual Bleeding: 6 people, 7.41%
  10. Multiple Allergies (allergy to multiple agents): 3 people, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Xyzal and have Tinnitus?

Check whether Tinnitus is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Tinnitus and when was it recovered:

Expand to all the drugs that have ingredients of levocetirizine dihydrochloride:

Alternative drugs to, pros and cons of Xyzal:

Common Xyzal side effects:

Browse all side effects of Xyzal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Tinnitus treatments and more:

COVID vaccines that are related to Tinnitus:

Common drugs associated with Tinnitus:

All the drugs that are associated with Tinnitus:

Common conditions associated with Tinnitus:

All the conditions that are associated with Tinnitus:

How the study uses the data?

The study uses data from the FDA. It is based on levocetirizine dihydrochloride (the active ingredients of Xyzal) and Xyzal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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