Yaz and Quincke's disease - a phase IV clinical study of FDA data


Quincke's disease is reported only by a few people who take Yaz.

The phase IV clinical study analyzes which people take Yaz and have Quincke's disease. It is created by eHealthMe based on reports of 39,594 people who have side effects while taking Yaz from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 26, 2023

39,594 people reported to have side effects when taking Yaz.
Among them, 3 people (0.01%) have Quincke's disease.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,093 Yaz users for its effectiveness, alternative drugs and more.

What is Quincke's disease?

Quincke's disease (a form of localized swelling of the deeper layers of the skin and fatty tissues beneath the skin) is found to be associated with 963 drugs and 479 conditions by eHealthMe.

Number of Yaz and Quincke's disease reports submitted per year:

Could Yaz cause Quincke's disease?

Gender of people who have Quincke's disease when taking Yaz *:

  • female: 50 %
  • male: 50 %

Age of people who have Quincke's disease when taking Yaz *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 50 %
  • 20-29: 0.0 %
  • 30-39: 50 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Yaz *:

  1. Zyrtec: 1 person, 33.33%
  2. Yasmin: 1 person, 33.33%
  3. Vitamin D2: 1 person, 33.33%
  4. Tamiflu: 1 person, 33.33%
  5. Symbicort: 1 person, 33.33%
  6. Singulair: 1 person, 33.33%
  7. Plendil: 1 person, 33.33%
  8. Lexapro: 1 person, 33.33%
  9. Amoxicillin: 1 person, 33.33%
  10. Allegra: 1 person, 33.33%

Common side effects people have besides Quincke's disease *:

  1. Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 33.33%
  2. Skin Burning Sensation: 1 person, 33.33%
  3. Skin Blushing/flushing (a sudden reddening of the face, neck): 1 person, 33.33%
  4. Rash Pruritic (redness with itching): 1 person, 33.33%
  5. Nausea And Vomiting: 1 person, 33.33%
  6. Nausea (feeling of having an urge to vomit): 1 person, 33.33%
  7. Infusion Related Reaction: 1 person, 33.33%
  8. Indigestion: 1 person, 33.33%
  9. Gallbladder Disorder: 1 person, 33.33%
  10. Cholecystitis Chronic (long lasting infection of gallbladder): 1 person, 33.33%

Common conditions people have *:

  1. Premenstrual Syndrome: 1 person, 33.33%
  2. Menstruation Irregular: 1 person, 33.33%
  3. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Yaz and have Quincke's disease?

Check whether Quincke's disease is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Quincke's disease and when was it recovered:

Expand to all the drugs that have ingredients of drospirenone; ethinyl estradiol:

Alternative drugs to, pros and cons of Yaz:

  • Yaz (41,093 reports)

Common Yaz side effects:

Browse all side effects of Yaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Quincke's disease treatments and more:

COVID vaccines that are related to Quincke's disease:

Common drugs associated with Quincke's disease:

All the drugs that are associated with Quincke's disease:

Common conditions associated with Quincke's disease:

All the conditions that are associated with Quincke's disease:

How the study uses the data?

The study uses data from the FDA. It is based on drospirenone; ethinyl estradiol (the active ingredients of Yaz) and Yaz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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