Zantac 75 and Gastritis - a phase IV clinical study of FDA data


Gastritis is found among people who take Zantac 75, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Zantac 75 and have Gastritis. It is created by eHealthMe based on reports of 3,532 people who have side effects when taking Zantac 75 from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 28, 2022

3,532 people reported to have side effects when taking Zantac 75.
Among them, 6 people (0.17%) have Gastritis.

What is Zantac 75?

Zantac 75 has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,713 Zantac 75 users for its effectiveness, alternative drugs and more.

What is Gastritis?

Gastritis (inflammation of stomach) is found to be associated with 2,567 drugs and 1,859 conditions by eHealthMe.

Number of Zantac 75 and Gastritis reports submitted per year:

Could Zantac 75 cause Gastritis?

Time on Zantac 75 when people have Gastritis *:

  • < 1 month: 33.33 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Gastritis when taking Zantac 75 *:

  • female: 80 %
  • male: 20 %

Age of people who have Gastritis when taking Zantac 75 *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Zantac 75 *:

  1. Sucralfate: 3 people, 50.00%
  2. Furosemide: 3 people, 50.00%
  3. Aspirin: 2 people, 33.33%
  4. Welchol: 1 person, 16.67%
  5. Lasix: 1 person, 16.67%
  6. Januvia: 1 person, 16.67%
  7. Diovan: 1 person, 16.67%
  8. Ativan: 1 person, 16.67%

Common side effects people have besides Gastritis *:

  1. Diarrhea: 4 people, 66.67%
  2. Weight Decreased: 3 people, 50.00%
  3. Weakness: 1 person, 16.67%
  4. Visual Impairment: 1 person, 16.67%
  5. Renal Cyst (kidney cyst): 1 person, 16.67%
  6. Migraine (headache): 1 person, 16.67%
  7. Hypoaesthesia Oral (reduced sense of touch or sensation in mouth): 1 person, 16.67%
  8. Haemangioma Of Liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver): 1 person, 16.67%

Common conditions people have *:

  1. Joint Swelling: 3 people, 50.00%
  2. High Blood Pressure: 3 people, 50.00%
  3. Flatulence (flatus expelled through the anus): 2 people, 33.33%
  4. Abdominal Pain: 2 people, 33.33%
  5. Type 2 Diabetes: 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Zantac 75 and have Gastritis?

Check whether Gastritis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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Common drugs associated with Gastritis:

All the drugs that are associated with Gastritis:

Common conditions associated with Gastritis:

All the conditions that are associated with Gastritis:

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac 75) and Zantac 75 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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