Zantac and Oesophageal carcinoma - a phase IV clinical study of FDA data
Summary:
Oesophageal carcinoma is found among people who take Zantac, especially for people who are male, 60+ old, have been taking the drug for 10+ years.
The phase IV clinical study analyzes which people take Zantac and have Oesophageal carcinoma. It is created by eHealthMe based on reports of 365,012 people who have side effects when taking Zantac from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
365,012 people reported to have side effects when taking Zantac.
Among them, 18,962 people (5.19%) have Oesophageal carcinoma.
What is Zantac?
Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 367,145 Zantac users for its effectiveness, alternative drugs and more.
What is Oesophageal carcinoma?
Oesophageal carcinoma (cancer tumour of oesophagus) is found to be associated with 759 drugs and 388 conditions by eHealthMe.
Number of Zantac and Oesophageal carcinoma reports submitted per year:

Time on Zantac when people have Oesophageal carcinoma *:
Gender of people who have Oesophageal carcinoma when taking Zantac*:
Age of people who have Oesophageal carcinoma when taking Zantac *:
Common drugs people take besides Zantac *:
Common side effects people have besides Oesophageal carcinoma *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Zantac and have Oesophageal carcinoma?
Check whether Oesophageal carcinoma is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Oesophageal carcinoma and when was it recovered:
Expand to all the drugs that have ingredients of ranitidine hydrochloride:
Alternative drugs to, pros and cons of Zantac:
- Zantac (367,145 reports)
Common Zantac side effects:
- Prostate cancer: 42,886 reports
- Colon cancer: 38,454 reports
- Renal cell carcinoma (a kidney cancer): 31,691 reports
- Breast cancer: 31,011 reports
- Bladder cancer: 28,922 reports
- Gastric cancer (stomach cancer): 14,090 reports
- Pancreatic carcinoma (pancreatic cancer): 11,318 reports
Browse all side effects of Zantac:
a b c d e f g h i j k l m n o p q r s t u v w x y zOesophageal carcinoma treatments and more:
- Oesophageal carcinoma (33,075 reports)
COVID vaccines that are related to Oesophageal carcinoma:
- Oesophageal carcinoma in Moderna COVID Vaccine
- Oesophageal carcinoma in Pfizer BioNTech Covid Vaccine
- Oesophageal carcinoma in Johnson and Johnson Covid Vaccine
Common drugs associated with Oesophageal carcinoma:
- Zantac: 18,962 reports
- Ranitidine: 8,936 reports
- Nexium: 245 reports
- Omeprazole: 199 reports
- Prednisolone: 172 reports
- Methotrexate: 170 reports
- Prednisone: 162 reports
- Humira: 148 reports
- Clozaril: 136 reports
- Enbrel: 125 reports
All the drugs that are associated with Oesophageal carcinoma:
- Oesophageal carcinoma (759 drugs)
Common conditions associated with Oesophageal carcinoma:
- Indigestion: 15,098 reports
- Gastric ulcer: 1,508 reports
- Rheumatoid arthritis: 271 reports
- Multiple sclerosis: 175 reports
- High blood pressure: 171 reports
- Osteoporosis: 156 reports
All the conditions that are associated with Oesophageal carcinoma:
- Oesophageal carcinoma (388 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac) and Zantac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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