Zantac and Oesophageal pain - a phase IV clinical study of FDA data
Summary:
Oesophageal pain is found among people who take Zantac, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Zantac and have Oesophageal pain. It is created by eHealthMe based on reports of 365,012 people who have side effects when taking Zantac from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
365,012 people reported to have side effects when taking Zantac.
Among them, 106 people (0.03%) have Oesophageal pain.
What is Zantac?
Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 367,146 Zantac users for its effectiveness, alternative drugs and more.
What is Oesophageal pain?
Oesophageal pain is found to be associated with 971 drugs and 547 conditions by eHealthMe.
Number of Zantac and Oesophageal pain reports submitted per year:

Time on Zantac when people have Oesophageal pain *:
Gender of people who have Oesophageal pain when taking Zantac*:
Age of people who have Oesophageal pain when taking Zantac *:
Common drugs people take besides Zantac *:
Common side effects people have besides Oesophageal pain *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Zantac and have Oesophageal pain?
Check whether Oesophageal pain is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Oesophageal pain and when was it recovered:
Expand to all the drugs that have ingredients of ranitidine hydrochloride:
Alternative drugs to, pros and cons of Zantac:
- Zantac (367,146 reports)
Common Zantac side effects:
- Prostate cancer: 42,886 reports
- Colon cancer: 38,454 reports
- Renal cell carcinoma (a kidney cancer): 31,691 reports
- Breast cancer: 31,011 reports
- Bladder cancer: 28,922 reports
- Gastric cancer (stomach cancer): 14,090 reports
- Pancreatic carcinoma (pancreatic cancer): 11,333 reports
Browse all side effects of Zantac:
a b c d e f g h i j k l m n o p q r s t u v w x y zOesophageal pain treatments and more:
- Oesophageal pain (4,333 reports)
COVID vaccines that are related to Oesophageal pain:
- Oesophageal pain in Moderna COVID Vaccine
- Oesophageal pain in Pfizer BioNTech Covid Vaccine
- Oesophageal pain in Johnson and Johnson Covid Vaccine
Common drugs associated with Oesophageal pain:
- Nexium: 342 reports
- Prednisone: 336 reports
- Pradaxa: 268 reports
- Gabapentin: 224 reports
- Furosemide: 213 reports
- Cymbalta: 209 reports
- Fosamax: 208 reports
- Prilosec: 193 reports
- Aspirin: 181 reports
- Omeprazole: 167 reports
All the drugs that are associated with Oesophageal pain:
- Oesophageal pain (971 drugs)
Common conditions associated with Oesophageal pain:
- Gastroesophageal reflux disease: 264 reports
- Atrial fibrillation/flutter: 217 reports
- Osteoporosis: 206 reports
- High blood pressure: 204 reports
- Stress and anxiety: 176 reports
All the conditions that are associated with Oesophageal pain:
- Oesophageal pain (547 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac) and Zantac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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