Zantac and Ototoxicity - a phase IV clinical study of FDA data

Summary:

Ototoxicity is reported only by a few people who take Zantac.

The phase IV clinical study analyzes which people take Zantac and have Ototoxicity. It is created by eHealthMe based on reports of 213,948 people who have side effects while taking Zantac from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On Jul, 18, 2022

213,948 people reported to have side effects when taking Zantac.
Among them, 3 people (0.0%) have Ototoxicity.


What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 216,074 Zantac users for its effectiveness, alternative drugs and more.

What is Ototoxicity?

Ototoxicity (damage to the ear) is found to be associated with 595 drugs and 333 conditions by eHealthMe.

Number of Zantac and Ototoxicity reports submitted per year:

Could Zantac cause Ototoxicity?

Time on Zantac when people have Ototoxicity *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Ototoxicity when taking Zantac *:

  • female: 33.33 %
  • male: 66.67 %

Age of people who have Ototoxicity when taking Zantac *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 33.33 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 66.67 %

Common drugs people take besides Zantac *:

  1. Lasix: 2 people, 66.67%
  2. Kytril: 1 person, 33.33%
  3. Azithromycin: 1 person, 33.33%
  4. Bactrim: 1 person, 33.33%
  5. Cisplatin: 1 person, 33.33%
  6. Creon: 1 person, 33.33%
  7. Decadron: 1 person, 33.33%
  8. Gentamicin: 1 person, 33.33%
  9. Vitamin D: 1 person, 33.33%
  10. Ventolin: 1 person, 33.33%

Common side effects people have besides Ototoxicity *:

  1. Tinnitus (a ringing in the ears): 2 people, 66.67%
  2. Weight Decreased: 1 person, 33.33%
  3. Tympanic Membrane Disorder (disease of ear drum): 1 person, 33.33%
  4. Pulmonary Function Test Decreased: 1 person, 33.33%
  5. Heart Rate Increased: 1 person, 33.33%
  6. Hair Disorder: 1 person, 33.33%
  7. Fever: 1 person, 33.33%
  8. Deafness Neurosensory: 1 person, 33.33%
  9. Cystic Fibrosis (disease of the secretary glands): 1 person, 33.33%
  10. Cough: 1 person, 33.33%

Common conditions people have *:

  1. Cystic Fibrosis (disease of the secretary glands): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Zantac and have Ototoxicity?

Check whether Ototoxicity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of Zantac:

Ototoxicity treatments and more:

COVID vaccines that are related to Ototoxicity:

How severe was Ototoxicity and when was it recovered:

Expand to all the drugs that have ingredients of ranitidine hydrochloride:

Common drugs associated with Ototoxicity:

All the drugs that are associated with Ototoxicity:

All the conditions that are associated with Ototoxicity:

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac) and Zantac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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