Zegerid and Insomnia - a phase IV clinical study of FDA data
Summary:
Insomnia is found among people who take Zegerid, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Zegerid and have Insomnia. It is created by eHealthMe based on reports of 2,937 people who have side effects when taking Zegerid from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
2,937 people reported to have side effects when taking Zegerid.
Among them, 44 people (1.5%) have Insomnia.
What is Zegerid?
Zegerid has active ingredients of omeprazole; sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,168 Zegerid users for its effectiveness, alternative drugs and more.
What is Insomnia?
Insomnia (sleeplessness) is found to be associated with 4,666 drugs and 4,975 conditions by eHealthMe.
Number of Zegerid and Insomnia reports submitted per year:

Time on Zegerid when people have Insomnia *:
- < 1 month: 75 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 25 %
- 10+ years: 0.0 %
Gender of people who have Insomnia when taking Zegerid *:
- female: 59.52 %
- male: 40.48 %
Age of people who have Insomnia when taking Zegerid *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 3.57 %
- 30-39: 3.57 %
- 40-49: 21.43 %
- 50-59: 17.86 %
- 60+: 53.57 %
Common drugs people take besides Zegerid *:
- Prevacid: 7 people, 15.91%
- Protonix: 7 people, 15.91%
- Lisinopril: 6 people, 13.64%
- Nexium: 6 people, 13.64%
- Crestor: 6 people, 13.64%
- Klonopin: 5 people, 11.36%
- Metoclopramide: 5 people, 11.36%
- Prilosec: 5 people, 11.36%
- Lunesta: 4 people, 9.09%
- Ativan: 4 people, 9.09%
Common side effects people have besides Insomnia *:
- Nausea (feeling of having an urge to vomit): 13 people, 29.55%
- Fatigue (feeling of tiredness): 12 people, 27.27%
- Stress And Anxiety: 12 people, 27.27%
- Breathing Difficulty: 10 people, 22.73%
- Weakness: 10 people, 22.73%
- Agitation (state of anxiety or nervous excitement): 9 people, 20.45%
- Depression: 8 people, 18.18%
- Hypoaesthesia (reduced sense of touch or sensation): 8 people, 18.18%
- High Blood Pressure: 8 people, 18.18%
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 7 people, 15.91%
Common conditions people have *:
- High Blood Cholesterol: 9 people, 20.45%
- Depression: 7 people, 15.91%
- High Blood Pressure: 6 people, 13.64%
- Quit Smoking: 5 people, 11.36%
- Stress And Anxiety: 5 people, 11.36%
- Nausea (feeling of having an urge to vomit): 4 people, 9.09%
- Indigestion: 4 people, 9.09%
- Pain: 4 people, 9.09%
- Seasonal Allergy (allergic condition due to certain season): 4 people, 9.09%
- Rashes (redness): 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Zegerid and have Insomnia?
Check whether Insomnia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Insomnia and when was it recovered:
Expand to all the drugs that have ingredients of omeprazole; sodium bicarbonate:
Alternative drugs to, pros and cons of Zegerid:
- Zegerid (3,168 reports)
Common Zegerid side effects:
- Chronic kidney disease: 684 reports
- Acute kidney failure: 309 reports
- Drug ineffective: 214 reports
- Pain: 204 reports
- Fatigue (feeling of tiredness): 150 reports
- Stress and anxiety: 139 reports
Browse all side effects of Zegerid:
a b c d e f g h i j k l m n o p q r s t u v w x y zInsomnia treatments and more:
- Insomnia (388,309 reports)
COVID vaccines that are related to Insomnia:
- Insomnia in Moderna COVID Vaccine
- Insomnia in Pfizer BioNTech Covid Vaccine
- Insomnia in Johnson and Johnson Covid Vaccine
Common drugs associated with Insomnia:
- Prednisone: 11,837 reports
- Aspirin: 10,926 reports
- Lyrica: 10,535 reports
- Cymbalta: 9,690 reports
- Seroquel: 7,933 reports
- Methotrexate: 7,563 reports
- Humira: 7,415 reports
- Omeprazole: 7,192 reports
- Gabapentin: 7,176 reports
- Synthroid: 7,110 reports
All the drugs that are associated with Insomnia:
- Insomnia (4,666 drugs)
Common conditions associated with Insomnia:
- Depression: 16,686 reports
- Pain: 12,769 reports
- Multiple sclerosis: 12,002 reports
- High blood pressure: 11,095 reports
- Rheumatoid arthritis: 10,870 reports
- Stress and anxiety: 9,545 reports
All the conditions that are associated with Insomnia:
- Insomnia (4,975 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on omeprazole; sodium bicarbonate (the active ingredients of Zegerid) and Zegerid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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