Zide and Hereditary angioedema - a phase IV clinical study of FDA data

Summary:

Hereditary angioedema is found among people who take Zide, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Zide and have Hereditary angioedema. It is created by eHealthMe based on reports of 157,466 people who have side effects when taking Zide from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Feb, 06, 2023

157,466 people reported to have side effects when taking Zide.
Among them, 126 people (0.08%) have Hereditary angioedema.


What is Zide?

Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 161,955 Zide users for its effectiveness, alternative drugs and more.

What is Hereditary angioedema?

Hereditary angioedema (recurrent episodes of severe swelling) is found to be associated with 948 drugs and 469 conditions by eHealthMe.

Number of Zide and Hereditary angioedema reports submitted per year:

Could Zide cause Hereditary angioedema?

Time on Zide when people have Hereditary angioedema *:

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Gender of people who have Hereditary angioedema when taking Zide*:

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Age of people who have Hereditary angioedema when taking Zide *:

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Common drugs people take besides Zide *:

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Common side effects people have besides Hereditary angioedema *:

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Common conditions people have *:

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* Approximation only. Some reports may have incomplete information.

Do you take Zide and have Hereditary angioedema?

Check whether Hereditary angioedema is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Hereditary angioedema and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide:

Alternative drugs to, pros and cons of Zide:

  • Zide (161,955 reports)

Common Zide side effects:

Browse all side effects of Zide:

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Hereditary angioedema treatments and more:

COVID vaccines that are related to Hereditary angioedema:

Common drugs associated with Hereditary angioedema:

All the drugs that are associated with Hereditary angioedema:

Common conditions associated with Hereditary angioedema:

All the conditions that are associated with Hereditary angioedema:

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Zide) and Zide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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