Zofran and Quincke's disease - a phase IV clinical study of FDA data

Summary:

Quincke's disease is found among people who take Zofran, especially for people who are female, 40-49 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Zofran and have Quincke's disease. It is created by eHealthMe based on reports of 83,138 people who have side effects when taking Zofran from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 06, 2023

83,138 people reported to have side effects when taking Zofran.
Among them, 293 people (0.35%) have Quincke's disease.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 84,336 Zofran users for its effectiveness, alternative drugs and more.

What is Quincke's disease?

Quincke's disease (a form of localized swelling of the deeper layers of the skin and fatty tissues beneath the skin) is found to be associated with 959 drugs and 476 conditions by eHealthMe.

Number of Zofran and Quincke's disease reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Zofran and have Quincke's disease?

Check whether Quincke's disease is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Quincke's disease and when was it recovered:

Quincke's disease in Zofran

Expand to all the drugs that have ingredients of ondansetron hydrochloride:

Quincke's disease and drugs with ingredients of ondansetron hydrochloride (203 reports)

Alternative drugs to, pros and cons of Zofran:

Zofran (84,336 reports)

Common Zofran side effects:

Fatigue (feeling of tiredness): 8,640 reports
Nausea and vomiting: 8,106 reports
Diarrhea: 7,770 reports
Indigestion: 7,679 reports
Pain: 7,289 reports
Stress and anxiety: 5,464 reports

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Quincke's disease treatments and more:

Quincke's disease (16,202 reports)

COVID vaccines that are related to Quincke's disease:

Common drugs associated with Quincke's disease:

All the drugs that are associated with Quincke's disease:

Quincke's disease (959 drugs)

Common conditions associated with Quincke's disease:

Hereditary angioedema: 1,067 reports
Preventive health care: 680 reports

All the conditions that are associated with Quincke's disease:

Quincke's disease (476 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron hydrochloride (the active ingredients of Zofran) and Zofran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.