Zoloft and Aneurysm - a phase IV clinical study of FDA data


Aneurysm is found among people who take Zoloft, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Zoloft and have Aneurysm. It is created by eHealthMe based on reports of 122,998 people who have side effects when taking Zoloft from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 01, 2023

122,998 people reported to have side effects when taking Zoloft.
Among them, 73 people (0.06%) have Aneurysm.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 132,552 Zoloft users for its effectiveness, alternative drugs and more.

What is Aneurysm?

Aneurysm (enlargement of an artery caused by a weakening of the artery wall) is found to be associated with 1,275 drugs and 694 conditions by eHealthMe.

Number of Zoloft and Aneurysm reports submitted per year:

Could Zoloft cause Aneurysm?

Time on Zoloft when people have Aneurysm *:

  • < 1 month: 10 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 30 %
  • 5 - 10 years: 10 %
  • 10+ years: 10 %

Gender of people who have Aneurysm when taking Zoloft *:

  • female: 66.15 %
  • male: 33.85 %

Age of people who have Aneurysm when taking Zoloft *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.52 %
  • 40-49: 15.22 %
  • 50-59: 30.43 %
  • 60+: 47.83 %

Common drugs people take besides Zoloft *:

  1. Xanax: 22 people, 30.14%
  2. Crestor: 21 people, 28.77%
  3. Jakafi: 17 people, 23.29%
  4. Clopidogrel: 17 people, 23.29%
  5. Vioxx: 12 people, 16.44%
  6. Lyrica: 10 people, 13.70%
  7. Vitamin D: 10 people, 13.70%
  8. Aspirin: 10 people, 13.70%
  9. Protonix: 9 people, 12.33%
  10. Levothyroxine Sodium: 9 people, 12.33%

Common side effects people have besides Aneurysm *:

  1. High Blood Pressure: 29 people, 39.73%
  2. Nausea (feeling of having an urge to vomit): 27 people, 36.99%
  3. Pain: 27 people, 36.99%
  4. Malaise (a feeling of general discomfort or uneasiness): 27 people, 36.99%
  5. Hyperhidrosis (abnormally increased sweating): 26 people, 35.62%
  6. Fatigue (feeling of tiredness): 25 people, 34.25%
  7. Breathing Difficulty: 25 people, 34.25%
  8. Constipation: 25 people, 34.25%
  9. Chest Pain: 24 people, 32.88%
  10. Insomnia (sleeplessness): 22 people, 30.14%

Common conditions people have *:

  1. Insomnia (sleeplessness): 18 people, 24.66%
  2. Panic Disorder: 17 people, 23.29%
  3. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 17 people, 23.29%
  4. High Blood Pressure: 9 people, 12.33%
  5. Pain: 9 people, 12.33%
  6. Primary Myelofibrosis (primary disorder of the bone marrow): 8 people, 10.96%
  7. High Blood Cholesterol: 7 people, 9.59%
  8. Sleep Disorder: 7 people, 9.59%
  9. Neuropathy Peripheral (surface nerve damage): 7 people, 9.59%
  10. Spinal Cord Trauma: 6 people, 8.22%

* Approximation only. Some reports may have incomplete information.

Do you take Zoloft and have Aneurysm?

Check whether Aneurysm is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Aneurysm and when was it recovered:

Expand to all the drugs that have ingredients of sertraline hydrochloride:

Alternative drugs to, pros and cons of Zoloft:

Common Zoloft side effects:

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Aneurysm treatments and more:

COVID vaccines that are related to Aneurysm:

Common drugs associated with Aneurysm:

All the drugs that are associated with Aneurysm:

Common conditions associated with Aneurysm:

All the conditions that are associated with Aneurysm:

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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