Zolpidem and Hepatomegaly - a phase IV clinical study of FDA data

Summary:

Hepatomegaly is found among people who take Zolpidem, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Zolpidem and have Hepatomegaly. It is created by eHealthMe based on reports of 80,705 people who have side effects when taking Zolpidem from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 06, 2023

80,705 people reported to have side effects when taking Zolpidem.
Among them, 112 people (0.14%) have Hepatomegaly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 82,945 Zolpidem users for its effectiveness, alternative drugs and more.

What is Hepatomegaly?

Hepatomegaly (abnormal enlargement of the liver) is found to be associated with 2,353 drugs and 1,824 conditions by eHealthMe.

Number of Zolpidem and Hepatomegaly reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Zolpidem and have Hepatomegaly?

Check whether Hepatomegaly is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .

Related studies

How severe was Hepatomegaly and when was it recovered:

Hepatomegaly in Zolpidem

Expand to all the drugs that have ingredients of zolpidem tartrate:

Hepatomegaly and drugs with ingredients of zolpidem tartrate (323 reports)

Alternative drugs to, pros and cons of Zolpidem:

Zolpidem (82,945 reports)

Common Zolpidem side effects:

Drug ineffective: 4,544 reports
Fatigue (feeling of tiredness): 4,414 reports
Pain: 3,394 reports
Stress and anxiety: 3,364 reports
Diarrhea: 3,339 reports
Headache (pain in head): 3,204 reports

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Hepatomegaly treatments and more:

Hepatomegaly (18,638 reports)

COVID vaccines that are related to Hepatomegaly:

Common drugs associated with Hepatomegaly:

All the drugs that are associated with Hepatomegaly:

Hepatomegaly (2,353 drugs)

Common conditions associated with Hepatomegaly:

High blood pressure: 768 reports
Hiv infection: 683 reports
Rheumatoid arthritis: 600 reports
Pain: 556 reports

All the conditions that are associated with Hepatomegaly:

Hepatomegaly (1,824 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Zolpidem) and Zolpidem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.