Zolpidem and Ototoxicity - a phase IV clinical study of FDA data

Summary:

Ototoxicity is found among people who take Zolpidem, especially for people who are male, 50-59 old.

The phase IV clinical study analyzes which people take Zolpidem and have Ototoxicity. It is created by eHealthMe based on reports of 80,705 people who have side effects when taking Zolpidem from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Aug, 09, 2022

80,705 people reported to have side effects when taking Zolpidem.
Among them, 8 people (0.01%) have Ototoxicity.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 76,984 Zolpidem users for its effectiveness, alternative drugs and more.

What is Ototoxicity?

Ototoxicity (damage to the ear) is found to be associated with 598 drugs and 335 conditions by eHealthMe.

Number of Zolpidem and Ototoxicity reports submitted per year:

Gender of people who have Ototoxicity when taking Zolpidem *:

female: 0.0 %
male: 100 %

Age of people who have Ototoxicity when taking Zolpidem *:

Common drugs people take besides Zolpidem *:

Common side effects people have besides Ototoxicity *:

Overdose: 4 people, 50.00%
Tinnitus (a ringing in the ears): 2 people, 25.00%
Sudden Hearing Loss: 2 people, 25.00%
Sinusitis (inflammation of sinus): 2 people, 25.00%
Constipation: 2 people, 25.00%
Deafness Neurosensory: 2 people, 25.00%
General Physical Health Deterioration (weak health status): 2 people, 25.00%
Hypokalemia (low potassium): 2 people, 25.00%
Urinary Tract Infection: 1 person, 12.50%
Muscle Spasms (muscle contraction): 1 person, 12.50%

Common conditions people have *:

Pain: 6 people, 75.00%
Constipation: 5 people, 62.50%
Pain In Extremity: 3 people, 37.50%
Prostate Cancer: 2 people, 25.00%
Stress And Anxiety: 1 person, 12.50%
Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 12.50%
Oral Pain: 1 person, 12.50%
Nausea (feeling of having an urge to vomit): 1 person, 12.50%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 12.50%
Gastric Disorder (disease of stomach): 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Zolpidem and have Ototoxicity?

Check whether Ototoxicity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .

Related studies

Alternative drugs to, pros and cons of Zolpidem:

Zolpidem (76,984 reports)

Ototoxicity treatments and more:

Ototoxicity (1,631 reports)

COVID vaccines that are related to Ototoxicity:

How severe was Ototoxicity and when was it recovered:

Ototoxicity in Zolpidem

Expand to all the drugs that have ingredients of zolpidem tartrate:

Ototoxicity and drugs with ingredients of zolpidem tartrate (10 reports)

Common drugs associated with Ototoxicity:

Carboplatin: 234 reports
Cisplatin: 258 reports
Etoposide: 170 reports
Gentamicin: 147 reports

All the drugs that are associated with Ototoxicity:

Ototoxicity (598 drugs)

All the conditions that are associated with Ototoxicity:

Ototoxicity (335 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Zolpidem) and Zolpidem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.