Zometa and Ear popping - a phase IV clinical study of FDA data
Summary:
Ear popping is found among people who take Zometa, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.
The phase IV clinical study analyzes which people take Zometa and have Ear popping. It is created by eHealthMe based on reports of 68,309 people who have side effects when taking Zometa from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
68,309 people reported to have side effects when taking Zometa.
Among them, 169 people (0.25%) have Ear popping.
What is Zometa?
Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 68,659 Zometa users for its effectiveness, alternative drugs and more.
What is Ear popping?
Ear popping is found to be associated with 934 drugs and 590 conditions by eHealthMe.
Number of Zometa and Ear popping reports submitted per year:

Time on Zometa when people have Ear popping *:
Gender of people who have Ear popping when taking Zometa*:
Age of people who have Ear popping when taking Zometa *:
Common drugs people take besides Zometa *:
Common side effects people have besides Ear popping *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Zometa and have Ear popping?
Check whether Ear popping is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Ear popping and when was it recovered:
Expand to all the drugs that have ingredients of zoledronic acid:
Alternative drugs to, pros and cons of Zometa:
- Zometa (68,659 reports)
Common Zometa side effects:
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 12,597 reports
- Pain: 11,683 reports
- Stress and anxiety: 8,299 reports
- Fatigue (feeling of tiredness): 7,123 reports
- Osteomyelitis (infection of bone): 5,818 reports
Browse all side effects of Zometa:
a b c d e f g h i j k l m n o p q r s t u v w x y zEar popping treatments and more:
- Ear popping (1,371 reports)
COVID vaccines that are related to Ear popping:
- Ear popping in Moderna COVID Vaccine
- Ear popping in Pfizer BioNTech Covid Vaccine
- Ear popping in Johnson and Johnson Covid Vaccine
Common drugs associated with Ear popping:
All the drugs that are associated with Ear popping:
- Ear popping (934 drugs)
Common conditions associated with Ear popping:
- Osteoporosis: 264 reports
- High blood pressure: 112 reports
All the conditions that are associated with Ear popping:
- Ear popping (590 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Zometa) and Zometa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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