Zosyn and Organ failure - a phase IV clinical study of FDA data


Organ failure is found among people who take Zosyn, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Zosyn and have Organ failure. It is created by eHealthMe based on reports of 9,583 people who have side effects when taking Zosyn from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 25, 2022

9,583 people reported to have side effects when taking Zosyn.
Among them, 8 people (0.08%) have Organ failure.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 9,644 Zosyn users for its effectiveness, alternative drugs and more.

What is Organ failure?

Organ failure is found to be associated with 991 drugs and 593 conditions by eHealthMe.

Number of Zosyn and Organ failure reports submitted per year:

Could Zosyn cause Organ failure?

Time on Zosyn when people have Organ failure *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Organ failure when taking Zosyn *:

  • female: 37.5 %
  • male: 62.5 %

Age of people who have Organ failure when taking Zosyn *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 0.0 %
  • 50-59: 37.5 %
  • 60+: 50.0 %

Common drugs people take besides Zosyn *:

  1. Vancomycin: 6 people, 75.00%
  2. Plavix: 4 people, 50.00%
  3. Lisinopril: 3 people, 37.50%
  4. Protonix: 3 people, 37.50%
  5. Lipitor: 3 people, 37.50%
  6. Fentanyl: 3 people, 37.50%
  7. Trasylol: 2 people, 25.00%
  8. Diflucan: 2 people, 25.00%
  9. Coreg: 2 people, 25.00%
  10. Nasonex: 2 people, 25.00%

Common side effects people have besides Organ failure *:

  1. Haemoglobin Decreased: 2 people, 25.00%
  2. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 25.00%
  3. Pain: 2 people, 25.00%
  4. Nausea (feeling of having an urge to vomit): 2 people, 25.00%
  5. Depression: 2 people, 25.00%
  6. Death: 2 people, 25.00%
  7. Haematocrit Decreased: 2 people, 25.00%
  8. Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 2 people, 25.00%
  9. Cardiac Disorder: 2 people, 25.00%
  10. Fatigue (feeling of tiredness): 2 people, 25.00%

Common conditions people have *:

  1. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 25.00%
  2. Urinary Tract Infection: 1 person, 12.50%
  3. Stress And Anxiety: 1 person, 12.50%
  4. Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 12.50%
  5. Skin Ulcer: 1 person, 12.50%
  6. Pneumonia Pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs): 1 person, 12.50%
  7. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 1 person, 12.50%
  8. Lymphoma (cancer that begins in immune system cells): 1 person, 12.50%
  9. Lung Infection Pseudomonal (bacterial infection of lung by pseudomonas aeruginosa): 1 person, 12.50%
  10. Depression: 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Zosyn and have Organ failure?

Check whether Organ failure is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Organ failure and when was it recovered:

Expand to all the drugs that have ingredients of piperacillin sodium; tazobactam sodium:

Alternative drugs to, pros and cons of Zosyn:

Common Zosyn side effects:

Browse all side effects of Zosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Organ failure treatments and more:

COVID vaccines that are related to Organ failure:

Common drugs associated with Organ failure:

All the drugs that are associated with Organ failure:

Common conditions associated with Organ failure:

All the conditions that are associated with Organ failure:

How the study uses the data?

The study uses data from the FDA. It is based on piperacillin sodium; tazobactam sodium (the active ingredients of Zosyn) and Zosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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