Zyban and Ligament sprain - a phase IV clinical study of FDA data


Ligament sprain is found among people who take Zyban, especially for people who are female, 50-59 old.

The phase IV clinical study analyzes which people take Zyban and have Ligament sprain. It is created by eHealthMe based on reports of 7,728 people who have side effects when taking Zyban from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 12, 2022

7,728 people reported to have side effects when taking Zyban.
Among them, 6 people (0.08%) have Ligament sprain.

What is Zyban?

Zyban has active ingredients of bupropion hydrochloride. It is often used in quit smoking. eHealthMe is studying from 7,883 Zyban users for its effectiveness, alternative drugs and more.

What is Ligament sprain?

Ligament sprain (ligament stretched) is found to be associated with 1,289 drugs and 684 conditions by eHealthMe.

Number of Zyban and Ligament sprain reports submitted per year:

Could Zyban cause Ligament sprain?

Gender of people who have Ligament sprain when taking Zyban *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Ligament sprain when taking Zyban *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 33.33 %
  • 30-39: 16.67 %
  • 40-49: 0.0 %
  • 50-59: 50.0 %
  • 60+: 0.0 %

Common drugs people take besides Zyban *:

  1. Celebrex: 3 people, 50.00%
  2. Actemra: 3 people, 50.00%
  3. Plaquenil: 3 people, 50.00%
  4. Tylenol: 3 people, 50.00%
  5. Lipitor: 3 people, 50.00%
  6. Rezulin: 2 people, 33.33%
  7. Coumadin: 2 people, 33.33%
  8. Regular Insulin: 2 people, 33.33%
  9. Ibuprofen: 2 people, 33.33%
  10. Zoloft: 2 people, 33.33%

Common side effects people have besides Ligament sprain *:

  1. Fall: 4 people, 66.67%
  2. High Blood Pressure: 4 people, 66.67%
  3. Ear Pain: 4 people, 66.67%
  4. Abdominal Pain: 4 people, 66.67%
  5. Joint Pain: 4 people, 66.67%
  6. Urinary Tract Infection: 4 people, 66.67%
  7. Nasopharyngitis (inflammation of the nasopharynx): 4 people, 66.67%
  8. Nausea (feeling of having an urge to vomit): 4 people, 66.67%
  9. Insomnia (sleeplessness): 4 people, 66.67%
  10. Rhinorrhea (watery mucus discharge from the nose): 4 people, 66.67%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 50.00%
  2. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Zyban and have Ligament sprain?

Check whether Ligament sprain is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Ligament sprain and when was it recovered:

Expand to all the drugs that have ingredients of bupropion hydrochloride:

Alternative drugs to, pros and cons of Zyban:

Common Zyban side effects:

Browse all side effects of Zyban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Ligament sprain treatments and more:

COVID vaccines that are related to Ligament sprain:

Common drugs associated with Ligament sprain:

All the drugs that are associated with Ligament sprain:

Common conditions associated with Ligament sprain:

All the conditions that are associated with Ligament sprain:

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Zyban) and Zyban (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: