Zyprexa and Acute prerenal failure - a phase IV clinical study of FDA data

Summary:

Acute prerenal failure is found among people who take Zyprexa, especially for people who are male, 50-59 old, have been taking the drug for 6 - 12 months.

The phase IV clinical study analyzes which people take Zyprexa and have Acute prerenal failure. It is created by eHealthMe based on reports of 61,460 people who have side effects when taking Zyprexa from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 02, 2022

61,460 people reported to have side effects when taking Zyprexa.
Among them, 14 people (0.02%) have Acute prerenal failure.


What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 62,739 Zyprexa users for its effectiveness, alternative drugs and more.

What is Acute prerenal failure?

Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney) is found to be associated with 990 drugs and 559 conditions by eHealthMe.

Number of Zyprexa and Acute prerenal failure reports submitted per year:

Could Zyprexa cause Acute prerenal failure?

Time on Zyprexa when people have Acute prerenal failure *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Acute prerenal failure when taking Zyprexa *:

  • female: 46.15 %
  • male: 53.85 %

Age of people who have Acute prerenal failure when taking Zyprexa *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 9.09 %
  • 20-29: 0.0 %
  • 30-39: 9.09 %
  • 40-49: 18.18 %
  • 50-59: 36.36 %
  • 60+: 27.27 %

Common drugs people take besides Zyprexa *:

  1. Seroquel: 5 people, 35.71%
  2. Zoloft: 3 people, 21.43%
  3. Synthroid: 3 people, 21.43%
  4. Lasix: 3 people, 21.43%
  5. Prozac: 3 people, 21.43%
  6. Abilify: 3 people, 21.43%
  7. Metoprolol Succinate: 2 people, 14.29%
  8. Cardizem Cd: 2 people, 14.29%
  9. Lipitor: 2 people, 14.29%
  10. Valium: 2 people, 14.29%

Common side effects people have besides Acute prerenal failure *:

  1. Weight Increased: 6 people, 42.86%
  2. Nausea And Vomiting: 6 people, 42.86%
  3. Nausea (feeling of having an urge to vomit): 4 people, 28.57%
  4. Breathing Difficulty: 4 people, 28.57%
  5. Fatigue (feeling of tiredness): 4 people, 28.57%
  6. Weight Loss: 4 people, 28.57%
  7. Urinary Tract Infection: 4 people, 28.57%
  8. Diabetes: 4 people, 28.57%
  9. Dehydration (dryness resulting from the removal of water): 4 people, 28.57%
  10. Fever: 3 people, 21.43%

Common conditions people have *:

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 21.43%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 7.14%
  3. Insomnia (sleeplessness): 1 person, 7.14%
  4. Immunodeficiency Disorders: 1 person, 7.14%
  5. Gastrointestinal Stromal Tumor: 1 person, 7.14%
  6. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 7.14%
  7. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Zyprexa and have Acute prerenal failure?

Check whether Acute prerenal failure is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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Acute prerenal failure treatments and more:

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Common drugs associated with Acute prerenal failure:

All the drugs that are associated with Acute prerenal failure:

Common conditions associated with Acute prerenal failure:

All the conditions that are associated with Acute prerenal failure:

How the study uses the data?

The study uses data from the FDA. It is based on olanzapine (the active ingredients of Zyprexa) and Zyprexa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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