Zyprexa and Ototoxicity - a phase IV clinical study of FDA data

• Zyprexa (61,530 reports)

• Abasia (inability to walk): 129 reports
• Abdominal discomfort: 224 reports
• Abdominal distension: 270 reports
• Abdominal pain: 672 reports
• Abdominal pain upper: 565 reports
• Abnormal behavior: 951 reports
• Abnormal dreams: 203 reports
• Abnormal weight gain: 102 reports
• Abortion spontaneous (naturally occurring miscarriage): 182 reports
• Accidental overdose (therapeutic agent): 207 reports
• Activities of daily living impaired: 166 reports
• Acute kidney failure: 726 reports
• Acute myocardial infarction (acute heart attack): 130 reports
• Adverse drug reaction: 398 reports
• Adverse event: 254 reports
• Affective disorder (mental disorder): 101 reports
• Aggression: 1,112 reports
• Agitation (state of anxiety or nervous excitement): 2,164 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1,243 reports
• Akathisia (a movement disorder characterized by a feeling of inner restlessness): 620 reports
• Alanine aminotransferase increased: 888 reports
• Alcoholism (problems with alcohol): 235 reports
• Altered state of consciousness (altered state of mind): 266 reports
• Anaemia (lack of blood): 938 reports
• Anger: 448 reports
• Anhedonia (inability to experience pleasure from activities usually found enjoyable): 128 reports
• Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 210 reports
• Anosognosia (ignorance of the presence of disease): 390 reports
• Apathy: 228 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 728 reports
• Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 899 reports
• Arrhythmias (irregular heartbeat): 915 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 227 reports
• Arthropathy: 164 reports
• Aspartate aminotransferase increased: 865 reports
• Asthma: 267 reports
• Atherosclerosis (disorder of the arteries): 169 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 279 reports
• Back pain: 889 reports
• Balance disorder: 376 reports
• Bedwetting: 122 reports
• Bipolar disorder (mood disorder): 490 reports
• Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode): 138 reports
• Birth control: 151 reports
• Blindness: 163 reports
• Blood alkaline phosphatase increased: 318 reports
• Blood bilirubin increased: 157 reports
• Blood creatine phosphokinase increased: 894 reports
• Blood creatinine increased: 387 reports
• Blood glucose decreased: 205 reports
• Blood glucose increased: 1,649 reports
• Blood lactate dehydrogenase increased: 256 reports
• Blood potassium decreased: 137 reports
• Blood prolactin increased: 260 reports
• Blood sodium decreased: 191 reports
• Blood urea increased: 198 reports
• Body temperature increased: 157 reports
• Bone disorder: 128 reports
• Bone pain: 116 reports
• Bradycardia (abnormally slow heart action): 204 reports
• Breast cancer: 116 reports
• Breast pain: 108 reports
• Breathing difficulty: 1,396 reports
• Breathing - slowed or stopped: 220 reports
• Broken bone: 107 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 391 reports
• Burning sensation: 133 reports
• Cardiac arrest: 578 reports
• Cardiac disorder: 596 reports
• Cardiac failure: 321 reports
• Cardiac failure congestive: 486 reports
• Cardiac murmur (an heart sound in valve abnormality): 117 reports
• Cardiomyopathy (weakening of the heart muscle): 164 reports
• Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 398 reports
• Cataract (clouding of the lens inside the eye): 187 reports
• Catatonia (unresponsive to external stimuli): 169 reports
• Cellulitis (infection under the skin): 347 reports
• Cerebral haemorrhage (bleeding within the brain): 116 reports
• Cerebral infarction (less blood supply to brain resulting tissue damage): 145 reports
• Chest pain: 1,387 reports
• Chills (felling of cold): 227 reports
• Chronic kidney disease: 117 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 293 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 357 reports
• Colitis (inflammation of colon): 133 reports
• Completed suicide (act of taking one's own life): 1,053 reports
• Condition: 1,234 reports
• Confusion: 667 reports
• Confusional state: 1,312 reports
• Consciousness - decreased: 759 reports
• Constipation: 952 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 992 reports
• Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 341 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 253 reports
• Cough: 476 reports
• Coughing up blood: 105 reports
• C-reactive protein increased: 266 reports
• Crying: 234 reports
• Cuts and puncture wounds: 137 reports
• Death: 1,877 reports
• Decreased interest: 114 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 457 reports
• Dehydration (dryness resulting from the removal of water): 912 reports
• Delirium (wild excitement): 553 reports
• Delusion (a false belief or opinion): 677 reports
• Dementia (madness): 269 reports
• Dental caries: 128 reports
• Depressed level of consciousness: 605 reports
• Depressed mood: 238 reports
• Depression: 2,340 reports
• Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 169 reports
• Diabetes: 6,883 reports
• Diabetes mellitus inadequate control: 572 reports
• Diabetic complication: 166 reports
• Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 2,193 reports
• Diabetic nephropathy (diabetic kidney disease): 102 reports
• Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus): 528 reports
• Diabetic retinopathy (damage to the retina caused by complications of diabetes): 129 reports
• Diarrhea: 1,169 reports
• Difficulty in walking: 136 reports
• Diplopia (double vision): 158 reports
• Disability: 133 reports
• Discomfort: 110 reports
• Disease progression: 102 reports
• Disease recurrence: 121 reports
• Disseminated intravascular coagulation (systemic activation of blood coagulation): 117 reports
• Disturbance in attention: 593 reports
• Disturbance in social behavior: 433 reports
• Dizziness: 1,696 reports
• Drooling (drop saliva uncontrollably from the mouth): 142 reports
• Drowsiness: 2,232 reports
• Drug abuse and dependence: 413 reports
• Drug dependence: 263 reports
• Drug effect decreased: 199 reports
• Drug exposure during pregnancy: 710 reports
• Drug hypersensitivity: 227 reports
• Drug ineffective: 2,474 reports
• Drug intolerance (drug sensitivity): 118 reports
• Drug level increased: 184 reports
• Drug maladministration: 117 reports
• Drug toxicity: 508 reports
• Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 455 reports
• Dry mouth: 477 reports
• Dyskinesia (abnormality or impairment of voluntary movement): 1,159 reports
• Dyslipidaemia (abnormal amount of lipids): 238 reports
• Dysstasia (difficulty in standing): 120 reports
• Ear pain: 139 reports
• Eating disorder: 248 reports
• Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 105 reports
• Electrocardiogram qt prolonged: 531 reports
• Electrolyte imbalance: 119 reports
• Emotional disorder: 278 reports
• Emotional distress: 396 reports
• Encephalopathy (functioning of the brain is affected by some agent or condition): 177 reports
• Endocrine disorder (endocrine diseases are disorders of the endocrine system): 135 reports
• Enlarged heart: 226 reports
• Eosinophil count increased: 103 reports
• Eosinophilia (eosinophil count in the peripheral blood exceeds): 130 reports
• Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 204 reports
• Erection problems: 951 reports
• Erythema multiforme (a type of hypersensitivity reaction): 173 reports
• Euphoric mood (excessively happy but may become angry or irritable): 127 reports
• Extrapyramidal disorder (involuntary muscle spasms in the face and neck): 622 reports
• Eye disorder: 133 reports
• Eye pain: 111 reports
• Face oedema (swelling of face): 147 reports
• Faecal incontinence (a lack of control over passing stool): 113 reports
• Fainting (loss of consciousness and postural tone): 626 reports
• Fall: 1,733 reports
• Fatigue (feeling of tiredness): 2,302 reports
• Fear: 236 reports
• Febrile neutropenia (fever with reduced white blood cells): 117 reports
• Feeling cold: 117 reports
• Feeling hot: 114 reports
• Fever: 1,982 reports
• Fibromyalgia (a long-term condition which causes pain all over the body): 160 reports
• Flank pain (a distressing sensation experienced around the lower back and the upper abdomen): 113 reports
• Flatulence (flatus expelled through the anus): 127 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 151 reports
• Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 226 reports
• Food craving: 117 reports
• Gait disturbance: 718 reports
• Gallbladder disorder: 127 reports
• Gallstones (stone formation by bile component): 351 reports
• Gamma-glutamyltransferase increased: 396 reports
• Gastric ulcer (stomach ulcer): 197 reports
• Gastritis (inflammation of stomach): 240 reports
• Gastroenteritis (inflammation of stomach and intestine): 116 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 491 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 197 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 278 reports
• General physical health deterioration (weak health status): 1,120 reports
• Gestational diabetes (diabetes in pregnancy): 122 reports
• Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 256 reports
• Glycosuria (excretion of glucose into the urine): 186 reports
• Glycosylated haemoglobin increased: 232 reports
• Grand mal convulsion (a type of generalized seizure that affects the entire brain): 294 reports
• Gynecomastia (enlargement of the gland tissue of the male breast): 456 reports
• Haematemesis (vomiting of blood): 188 reports
• Haematochezia (passage of stools containing blood): 132 reports
• Haematocrit decreased: 309 reports
• Haematoma (collection of blood outside the blood vessels): 117 reports
• Haematuria (presence of blood in urine): 171 reports
• Haemoglobin decreased: 550 reports
• Haemorrhage (bleeding): 211 reports
• Haemorrhoids (a swollen vein or group of veins in the region of the anus): 130 reports
• Hair loss: 340 reports
• Hallucination, auditory (perceiving sounds without auditory stimulus): 714 reports
• Hallucinations (sensations that appear real but are created by your mind): 831 reports
• Hallucination, visual (seeing things that aren't there): 247 reports
• Headache (pain in head): 1,481 reports
• Head injury: 637 reports
• Heart attack: 1,029 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 378 reports
• Heart rate decreased: 114 reports
• Heart rate increased: 452 reports
• Heart rate irregular: 129 reports
• Heavy or prolong menstrual bleeding: 153 reports
• Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 117 reports
• Hepatic enzyme increased: 315 reports
• Hepatic failure (liver failure): 214 reports
• Hepatic steatosis (fatty liver disease): 393 reports
• Hepatitis (inflammation of the liver): 190 reports
• Hepatitis c: 171 reports
• Hepatocellular damage (liver damage): 105 reports
• Hepatomegaly (abnormal enlargement of the liver): 170 reports
• Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 162 reports
• High blood cholesterol: 2,876 reports
• High blood pressure: 2,627 reports
• Hip fracture: 138 reports
• Hoarseness or changing voice: 111 reports
• Homicidal ideation (thoughts about human killing another human): 166 reports
• Hospitalisation: 627 reports
• Hostility: 171 reports
• Hyperglycemia (high blood sugar): 1,656 reports
• Hyperhidrosis (abnormally increased sweating): 611 reports
• Hyperkalemia (damage to or disease of the kidney): 227 reports
• Hyperlipidaemia (presence of excess lipids in the blood): 652 reports
• Hypernatraemia (an abnormally high plasma concentration of sodium ions): 102 reports
• Hyperprolactinaemia (abnormally high levels of prolactin in the blood): 171 reports
• Hypersensitivity: 282 reports
• Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 115 reports
• Hypertriglyceridaemia (excess of triglycerides in the blood): 181 reports
• Hyperventilation: 105 reports
• Hypoaesthesia (reduced sense of touch or sensation): 557 reports
• Hypoglycemia (low blood sugar): 651 reports
• Hypokalemia (low potassium): 388 reports
• Hypomania (a mild form of mania, marked by elation and hyperactivity): 118 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 698 reports
• Hypophagia (reduced food intake): 123 reports
• Hypotension (abnormally low blood pressure): 1,171 reports
• Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions): 158 reports
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 258 reports
• Ill-defined disorder: 341 reports
• Impaired healing: 127 reports
• Inappropriate antidiuretic hormone secretion: 124 reports
• Incontinence (lack of moderation or self-control): 147 reports
• Indigestion: 259 reports
• Infection: 422 reports
• Inflammation: 136 reports
• Influenza like illness: 267 reports
• Injury: 1,175 reports
• Insomnia (sleeplessness): 2,063 reports
• Intentional overdose: 534 reports
• Intentional self-injury: 281 reports
• International normalised ratio increased: 105 reports
• Intervertebral disc protrusion (spinal disc protrusion): 126 reports
• Intestinal obstruction: 313 reports
• Iron deficiency anaemia: 106 reports
• Irritability: 616 reports
• Itching: 367 reports
• Joint pain: 565 reports
• Joint swelling: 187 reports
• Kidney stones: 134 reports
• Leukocytosis (increased white blood cells): 237 reports
• Leukopenia (less number of white blood cells in blood): 582 reports
• Limb injury: 102 reports
• Liver disorder (liver diseases): 306 reports
• Logorrhea: 108 reports
• Loss of consciousness: 1,180 reports
• Low density lipoprotein increased (cholesterol increased in blood): 113 reports
• Low tissue oxygen: 197 reports
• Lung disorder (lung disease): 170 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 155 reports
• Lymphocyte count decreased: 117 reports
• Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 191 reports
• Malaise (a feeling of general discomfort or uneasiness): 1,144 reports
• Malignant neoplasm progression (cancer tumour came back): 118 reports
• Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 130 reports
• Mania (a state of abnormally elevated or irritable mood): 868 reports
• Maternal drugs affecting foetus (chemical affecting the baby before birth taken by mother): 130 reports
• Maternal exposure during pregnancy (use of substance during pregnancy): 114 reports
• Memory loss: 1,242 reports
• Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 657 reports
• Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 317 reports
• Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 351 reports
• Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 170 reports
• Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 1,109 reports
• Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease): 265 reports
• Migraine (headache): 239 reports
• Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light): 166 reports
• Mitral valve incompetence (inefficient heart valve): 130 reports
• Mood swings (an extreme or rapid change in mood): 468 reports
• Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 249 reports
• Movement - uncontrolled or slow: 816 reports
• Movement - uncoordinated: 154 reports
• Multi-organ failure (multisystem organ failure): 130 reports
• Multiple drug overdose: 120 reports
• Multiple drug overdose intentional: 105 reports
• Muscle aches (muscle pain): 415 reports
• Muscle rigidity (muscle stiffness): 417 reports
• Muscle spasms (muscle contraction): 548 reports
• Muscle tightness: 117 reports
• Muscle twitching: 261 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 190 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 334 reports
• Mydriasis (a dilation of the pupil): 125 reports
• Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 179 reports
• Myocarditis (inflammation of heart muscle myocardium): 106 reports
• Nasopharyngitis (inflammation of the nasopharynx): 238 reports
• Nausea (feeling of having an urge to vomit): 1,970 reports
• Nausea and vomiting: 1,320 reports
• Neck pain: 265 reports
• Neoplasm malignant (cancer tumour): 136 reports
• Nervousness: 484 reports
• Nervous system disorder (a general class of medical conditions affecting the nervous system): 171 reports
• Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 1,283 reports
• Neuropathy peripheral (surface nerve damage): 569 reports
• Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 289 reports
• Neutrophil count increased (excess than normal number of neutrophil a type of blood cell): 134 reports
• Nightmares (unpleasant dreams): 242 reports
• Non-accidental overdose: 338 reports
• Nosebleed (bleeding from nose): 309 reports
• Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 187 reports
• Oedema (fluid collection in tissue): 434 reports
• Oedema lower limb (fluid collection in tissue of lower leg): 148 reports
• Oedema peripheral (superficial swelling): 820 reports
• Oropharyngeal pain: 151 reports
• Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 146 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 220 reports
• Osteomyelitis (infection of bone): 135 reports
• Osteonecrosis of jaw (death of bone of jaw): 152 reports
• Osteoporosis (bones weak and more likely to break): 165 reports
• Overdose: 2,414 reports
• Oxygen saturation decreased: 145 reports
• Pain: 1,249 reports
• Pain in extremity: 604 reports
• Pain in jaw: 161 reports
• Paleness (unusual lightness of skin colour): 170 reports
• Pancreatitis (inflammation of pancreas): 2,447 reports
• Pancreatitis acute (sudden inflammation of pancreas): 367 reports
• Pancreatitis chronic (chronic inflammation of pancreas): 130 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 371 reports
• Panic disorder: 453 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 451 reports
• Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 548 reports
• Parkinson's disease: 529 reports
• Pericardial effusion (fluid around the heart): 103 reports
• Peripheral swelling: 122 reports
• Persecutory delusion: 102 reports
• Personality change: 558 reports
• Personality disorder: 141 reports
• Platelet count increased: 104 reports
• Pleural effusion (water on the lungs): 233 reports
• Pneumonia: 1,479 reports
• Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 414 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 236 reports
• Polytraumatism (multiple trauma): 167 reports
• Post-traumatic stress disorder: 120 reports
• Premature baby: 171 reports
• Prescribed overdose: 1,246 reports
• Psoriasis (immune-mediated disease that affects the skin): 104 reports
• Psychiatric symptom: 166 reports
• Psychomotor hyperactivity (feelings of extreme restlessness): 219 reports
• Psychotic disorder: 1,276 reports
• Pulmonary congestion (congestion in the lungs): 143 reports
• Pulmonary embolism (blockage of the main artery of the lung): 927 reports
• Pulmonary hypertension (increase in blood pressure in the lung artery): 144 reports
• Pulmonary oedema (fluid accumulation in the lungs): 302 reports
• Quit smoking: 125 reports
• Rash erythematous (redness of the skin): 117 reports
• Rashes (redness): 909 reports
• Rectal haemorrhage (bleeding from anus): 229 reports
• Red blood cell count decreased: 227 reports
• Renal disorder (kidney disease): 300 reports
• Renal failure acute (rapid kidney dysfunction): 517 reports
• Renal failure chronic (long lasting kidney dysfunction): 111 reports
• Renal impairment (severely reduced kidney function): 274 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 418 reports
• Respiratory depression (respiration has a rate below 12 breaths): 185 reports
• Respiratory disorder (respiratory disease): 144 reports
• Respiratory distress (difficulty in breathing): 140 reports
• Restless leg syndrome (a powerful urge to move your legs): 158 reports
• Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 772 reports
• Rib fracture: 121 reports
• Road traffic accident: 373 reports
• Salivary hypersecretion (excess saliva secretion): 220 reports
• Schizoaffective disorder (a mental disorder characterized by disordered thought): 151 reports
• Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 698 reports
• Schizophreniform disorder (mental disorder is diagnosed when the symptom criteria for schizophrenia are met, but the duration is too short and social and occupational functioning): 101 reports
• Sedation: 1,752 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 286 reports
• Self injurious behavior: 114 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 427 reports
• Septic shock (shock due to blood infection): 108 reports
• Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 186 reports
• Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 135 reports
• Sinus bradycardia (an unusually slow heartbeat due to heart disease): 103 reports
• Sinusitis (inflammation of sinus): 234 reports
• Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 216 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 111 reports
• Skin discoloration: 147 reports
• Sleep apnea syndrome: 302 reports
• Sleep disorder: 414 reports
• Sleep walking (walking during sleep): 179 reports
• Social avoidant behavior: 164 reports
• Sopor (sleep): 161 reports
• Speech disorder: 662 reports
• Speech impairment (adult) (inability to speak (adult)): 787 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 203 reports
• Stable angina (a constant chest pain): 161 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 134 reports
• Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 102 reports
• Stomatitis (inflammation of mucous membrane of mouth): 111 reports
• Stress and anxiety: 2,469 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 694 reports
• Stupor (lack of critical cognitive function and level of consciousness): 155 reports
• Suicidal ideation: 1,500 reports
• Suicide attempt: 1,931 reports
• Swallowing difficulty: 748 reports
• Sweating increased (excess sweating): 167 reports
• Swelling: 209 reports
• Swelling face: 128 reports
• Tachypnea: 101 reports
• Tardive dyskinesia (a disorder that involves involuntary movements): 778 reports
• Taste - impaired: 104 reports
• The flu (the flu is caused by an influenza virus): 167 reports
• Therapeutic agent toxicity (poisoning by ability to cure substance): 118 reports
• Thirst: 247 reports
• Thirst - excessive: 422 reports
• Thrombocytopenia (decrease of platelets in blood): 1,153 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 299 reports
• Tinnitus (a ringing in the ears): 130 reports
• Tooth abscess (pus formation in tooth): 138 reports
• Toothaches (tooth pain): 147 reports
• Tooth loss: 104 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 236 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 1,408 reports
• Tricuspid valve incompetence (inefficient heart valve): 105 reports
• Type 1 diabetes: 668 reports
• Type 2 diabetes: 3,016 reports
• Unresponsive to stimuli: 148 reports
• Upper respiratory tract infection: 228 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 366 reports
• Urinary retention (the inability to completely or partially empty the bladder): 327 reports
• Urinary tract infection: 789 reports
• Urination - excessive volume: 311 reports
• Urination - painful: 254 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 160 reports
• Vaginal bleeding: 105 reports
• Ventricular fibrillation (abnormally irregular heart rhythm): 108 reports
• Viral infection: 137 reports
• Vision blurred: 956 reports
• Visual acuity reduced (reduced clearness of vision): 221 reports
• Visual disturbance: 118 reports
• Visual impairment: 294 reports
• Weakness: 1,669 reports
• Weight decreased: 1,428 reports
• Weight increased: 5,874 reports
• Weight loss: 1,551 reports
• White blood cell count decreased: 777 reports
• White blood cell count increased: 520 reports
• Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 241 reports

• Ototoxicity (1,631 reports)

All the drugs that are associated with Ototoxicity:

• Ototoxicity (598 drugs)

All the conditions that are associated with Ototoxicity:

• Ototoxicity (336 conditions)

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