Zyrtec and Conjunctival oedema - a phase IV clinical study of FDA data


Conjunctival oedema is found among people who take Zyrtec, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Zyrtec and have Conjunctival oedema. It is created by eHealthMe based on reports of 94,387 people who have side effects when taking Zyrtec from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

94,387 people reported to have side effects when taking Zyrtec.
Among them, 6 people (0.01%) have Conjunctival oedema.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 99,160 Zyrtec users for its effectiveness, alternative drugs and more.

What is Conjunctival oedema?

Conjunctival oedema (conjunctival swelling) is found to be associated with 509 drugs and 318 conditions by eHealthMe.

Number of Zyrtec and Conjunctival oedema reports submitted per year:

Could Zyrtec cause Conjunctival oedema?

Gender of people who have Conjunctival oedema when taking Zyrtec *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Conjunctival oedema when taking Zyrtec *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 16.67 %
  • 40-49: 33.33 %
  • 50-59: 16.67 %
  • 60+: 33.33 %

Common drugs people take besides Zyrtec *:

  1. Amoxicillin: 2 people, 33.33%
  2. Zyvox: 1 person, 16.67%
  3. Clonidine: 1 person, 16.67%
  4. Flunisolide: 1 person, 16.67%
  5. Fluconazole: 1 person, 16.67%
  6. Florinef: 1 person, 16.67%
  7. Fish Oil: 1 person, 16.67%
  8. Famotidine: 1 person, 16.67%
  9. Doxazosin Mesylate: 1 person, 16.67%
  10. Dilaudid: 1 person, 16.67%

Common side effects people have besides Conjunctival oedema *:

  1. Rashes (redness): 3 people, 50.00%
  2. High Blood Pressure: 3 people, 50.00%
  3. Fever: 2 people, 33.33%
  4. Depression: 2 people, 33.33%
  5. Hyperkalemia (damage to or disease of the kidney): 2 people, 33.33%
  6. Dry Eyes (lack of adequate tears): 2 people, 33.33%
  7. Eye Pain: 2 people, 33.33%
  8. Eyelid Oedema (eyelids are swollen and contain excessive fluid): 2 people, 33.33%
  9. Face Oedema (swelling of face): 2 people, 33.33%
  10. Mucosal Inflammation (infection of mucous membrane): 2 people, 33.33%

Common conditions people have *:

  1. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 1 person, 16.67%
  2. Pain: 1 person, 16.67%
  3. Oedema (fluid collection in tissue): 1 person, 16.67%
  4. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 16.67%
  5. Multiple Myeloma (cancer of the plasma cells): 1 person, 16.67%
  6. High Blood Pressure: 1 person, 16.67%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 16.67%
  8. Cytomegalovirus Infection: 1 person, 16.67%
  9. Cellulitis (infection under the skin): 1 person, 16.67%
  10. Anaemia (lack of blood): 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and have Conjunctival oedema?

Check whether Conjunctival oedema is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Conjunctival oedema and when was it recovered:

Expand to all the drugs that have ingredients of cetirizine hydrochloride:

Alternative drugs to, pros and cons of Zyrtec:

Common Zyrtec side effects:

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Conjunctival oedema treatments and more:

COVID vaccines that are related to Conjunctival oedema:

All the drugs that are associated with Conjunctival oedema:

All the conditions that are associated with Conjunctival oedema:

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride (the active ingredients of Zyrtec) and Zyrtec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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