Methotrexate and Diarrhoea (expanded source)
Diarrhoea is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Humira, and have Psoriatic arthropathy. This review analyzes which people have Diarrhoea with Methotrexate. It is created by eHealthMe based on reports of 234,097 people who have side effects when taking Methotrexate from FDA and eHealthme, and is updated regularly.
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On Jan, 12, 2018
234,097 people reported to have side effects when taking Methotrexate.
Among them, 6,841 people (2.92%) have Diarrhoea
Number of reports submitted per year:
Time on Methotrexate when people have Diarrhoea *:
- < 1 month: 39.25 %
- 1 - 6 months: 18.17 %
- 6 - 12 months: 8.18 %
- 1 - 2 years: 8.74 %
- 2 - 5 years: 12.48 %
- 5 - 10 years: 8.46 %
- 10+ years: 4.58 %
Gender of people who have Diarrhoea when taking Methotrexate *:
- female: 73.4 %
- male: 26.6 %
Age of people who have Diarrhoea when taking Methotrexate *:
- 0-1: 1.16 %
- 2-9: 4.19 %
- 10-19: 6.17 %
- 20-29: 3.89 %
- 30-39: 6.83 %
- 40-49: 13.87 %
- 50-59: 26.45 %
- 60+: 37.45 %
Severity of Diarrhoea *:
- least: 14.29 %
- moderate: 53.57 %
- severe: 21.43 %
- most severe: 10.71 %
How people recovered from Diarrhoea *:
- while on drug: 15 %
- after off the drug: 15 %
- not yet: 70 %
Top conditions involved for these people *:
- Psoriatic Arthropathy (527 people, 7.70%)
- High Blood Pressure (420 people, 6.14%)
- Pain (411 people, 6.01%)
- Crohn's Disease (377 people, 5.51%)
- Preventive Health Care (281 people, 4.11%)
Top co-used drugs for these people *:
- Humira (1,473 people, 21.53%)
- Enbrel (1,300 people, 19.00%)
- Folic Acid (1,155 people, 16.88%)
- Prednisone (774 people, 11.31%)
- Plaquenil (563 people, 8.23%)
Top other side effects for these people *:
- Nausea (1,897 people, 27.73%)
- Nausea And Vomiting (1,753 people, 25.62%)
- Fever (1,048 people, 15.32%)
- Fatigue (1,014 people, 14.82%)
- Abdominal Pain (1,001 people, 14.63%)
* Approximation only. Some reports may have incomplete information.
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Want to find out more about the FDA reports used in the study? You can request them from FDA.
Do you have Diarrhoea when taking Methotrexate?
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Expand the study to include all drugs with the same ingredientsDiarrhoea and drugs with ingredients of methotrexate sodium.
Limit the study to reports from FDA onlyDiarrhoea and Methotrexate from FDA reports
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 234,881 users)
Diarrhoea has been reported by people with high blood pressure, multiple sclerosis, rheumatoid arthritis, crohn's disease, pain (latest reports from 302,027 Diarrhoea patients).
Browse all side effects of Methotrexatea b c d e f g h i j k l m n o p q r s t u v w x y z
Drugs that are associated with DiarrhoeaDiarrhoea
Could your condition cause DiarrhoeaDiarrhoea
Related publications that referenced our studies
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
What would happen?
Questions to the study
I have been recently given a diagnosis of rheumatoid arthritis. I had an atypical presentation with muscle pains in my thighs and later on wrist swelling. No joint pains or stiffness. Probably very early still. I am taking low dose steroids and MTX. The muscle pains improved but I developed ...
I have psoriatic arthritis and take methotrexate and plaquenil. I am doing well on these meds except for pain on the upper left side and around the back. The only relief is when I lay down. The pain is usually in the afternoon or when standing.
I HAVE RA FOR 6 YEARS STARTED COUGHING 2MONTHS AGO WENT MY PULMONARY DOCTOR. TOOK OUT PLEURAL FLUID TWICE IN 2 MONTHS. I HAVE BEEN TAKING METH0TREXATE. 25 MG 1 AWEEK FOR 6 YEARS. COULD THIS CAUSE PLEURAL FLUID AROUND LUNG; THANKS AGAIN JOHN SCALA
User posts to the study
Hi my names Tracy I’ve been taking methotrexate for about 1year stopped part way through year,as really don’t like taking the drug but been back in it for last few months and been having heart palpitations been to doc and they don’t seem worried about it,but I am!
I have been taking Saxenda for 3+ weeks now. Gently increasing in .6 dosages every week. On the last day of the 3 week on 1.8, i started experiencing severe abdominal cramps, burping(That smelled like a bad virus) and bad diarrhea. Thinking I had contracted a 24hr bug, I upped to 2.4. By the 3rd ...
Hi. I’m New to the group. Am back on Gleevec after changing to Sprycel for 4 yrs and developing low O2 sats at rest and small pleural effusion. Off and on with methotrexate for Psoriasis and PsA. My hair feels like it’s getting thinner and when I wash it I’m losing quite a bit. Anyone else ...
Hi, I am a 44 year old women who has just been diagnosed with ADD. I have been taking Ritalin for 2 weeks, I feel amazing but I have a really upset stomach & bad diahorreha. I usually have a pretty sensitive stomach & a bit of IBS.. My main question is I guess is my body just getting used to ...
I fell about a week ago and really scraped up my arm. However something very itchy started on my arm and nothing would fix it... I asked the pharmacist about this (as it is a weekend) and he said if I had a steroid cream I should try it... I did the ultimate wrong thing... We had some ...