Actos vs. Lisinopril: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Actos and Lisinopril. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 414,817 people who take Actos and Lisinopril, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
414,817 people who take Actos and Lisinopril are studied.
What is Actos?
Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,111 Actos users for its effectiveness, alternative drugs and more.
What is Lisinopril?
Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 325,399 Lisinopril users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Lisinopril (lisinopril)
- Actos (pioglitazone hydrochloride)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Actos:
- not at all: 2.73 %
- somewhat: 17.87 %
- moderate: 41.69 %
- high: 29.03 %
- very high: 8.68 %
Lisinopril:
- not at all: 1.54 %
- somewhat: 13.24 %
- moderate: 33.94 %
- high: 37.57 %
- very high: 13.71 %
Want to compare Actos with Lisinopril?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
Related studies
Alternative drugs to, pros and cons of:
- Actos (48,478 reports)
- Lisinopril (311,466 reports)
Common Actos side effects:
- Bladder cancer: 9,563 reports
- Weight decreased: 2,509 reports
- Weight increased: 2,205 reports
- Breathing difficulty: 2,144 reports
- Weakness: 1,950 reports
- Diarrhea: 1,859 reports
- Fatigue (feeling of tiredness): 1,857 reports
Browse all side effects of Actos:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Lisinopril side effects:
- Fatigue (feeling of tiredness): 20,962 reports
- Diarrhea: 17,320 reports
- Drug ineffective: 16,717 reports
- Pain: 15,476 reports
- Breathing difficulty: 15,475 reports
- High blood pressure: 14,865 reports
- Dizziness: 14,554 reports
Browse all side effects of Lisinopril:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on pioglitazone hydrochloride and lisinopril (the active ingredients of Actos and Lisinopril, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Toviaz and Zecuity drug interaction - 18 seconds ago
- Clopidogrel Bisulfate and Pulmonary Thrombosis - 29 seconds ago
- Herceptin and Bepreve drug interaction - 31 seconds ago
- Meclizine and Enamel Anomaly - 35 seconds ago
- Mirena and Systemic Lupus Erythematosus - 37 seconds ago
- Zyprexa and Alprazolam drug interaction - 44 seconds ago
- Capecitabine and Jejunal Perforation - 49 seconds ago
- Prandin and Skin Mass - 53 seconds ago
- Kineret and Thyroid Diseases - a minute ago
- Kanjinti and Diarrhea - a minute ago