Avandia vs. Avapro

Summary

We compare the side effects and drug effectiveness of Avandia and Avapro. The study is created by eHealthMe based on reports of 176,776 people who take Avandia and Avapro, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on rosiglitazone maleate and irbesartan (the active ingredients of Avandia and Avapro, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered.

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. (latest outcomes from Avandia 141,364 users)

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. (latest outcomes from Avapro 16,377 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Mar, 14, 2019

176,776 people who take Avandia and Avapro are studied.


Number of reports submitted per year:

Avandia vs Avapro drug comparison reports.

Drugs in this study:

  • Avapro (irbesartan)
  • Avandia (rosiglitazone maleate)

Most common side effects:

Avandia:
  1. Nausea (feeling of having an urge to vomit)
  2. Dyspnoea (difficult or laboured respiration)
  3. Diarrhoea
  4. Fatigue (feeling of tiredness)
  5. Dizziness
  6. Drug Ineffective
  7. Headache (pain in head)
  8. Asthenia (weakness)
  9. Fall
  10. Pain
Avapro:
  1. Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Cardiac Failure Congestive
  3. Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Cardiac Disorder
  6. Death
  7. Injury
  8. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  9. Dyspnoea (difficult or laboured respiration)
  10. Cardiovascular Disorder (heart diseases)

Most common side effects experienced by people in long term use:

Avandia:
  1. Renal Failure Acute (rapid kidney dysfunction)
  2. Dizziness
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  4. Nausea (feeling of having an urge to vomit)
  5. Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Renal Failure (kidney dysfunction)
  7. Back Pain
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Dyspnoea (difficult or laboured respiration)
  10. Diarrhoea
Avapro:
  1. Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Cardiac Failure Congestive
  3. Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Cardiac Disorder
  6. Death
  7. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  8. Cardiovascular Disorder (heart diseases)
  9. Dyspnoea (difficult or laboured respiration)
  10. Atrial Fibrillation (fibrillation of the muscles of the atria of the heart)

Drug effectiveness:

Avandia:
  • not at all: 0.87 %
  • somewhat: 11.16 %
  • moderate: 34.78 %
  • high: 41.16 %
  • very high: 12.03 %
Avapro:
  • not at all: 4.41 %
  • somewhat: 16.18 %
  • moderate: 36.76 %
  • high: 26.47 %
  • very high: 16.18 %

Do you take Avandia or Avapro?

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WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.