Bronkaid mist vs. Benadryl: side effect and effectiveness comparison - a phase IV clinical study

Summary:

We compare the side effects and drug effectiveness of Bronkaid mist and Benadryl. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 166,679 people who take Bronkaid mist and Benadryl, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 22, 2022

166,679 people who take Bronkaid mist and Benadryl are studied.

What is Bronkaid mist?

Bronkaid mist has active ingredients of epinephrine. It is often used in asthma. eHealthMe is studying from 27 Bronkaid mist users for its effectiveness, alternative drugs and more.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 80,675 Benadryl users for its effectiveness, alternative drugs and more.

Number of reports submitted per year:

Bronkaid mist vs Benadryl drug comparison reports.

Drugs being compared in this study:

Benadryl (diphenhydramine hydrochloride)
Bronkaid Mist (epinephrine)

Most common side effects of the drugs, overall:

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Most common side effects of the drugs, in long term (1+ years) use:

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Drug effectiveness:

Bronkaid Mist:

not at all: 2.9 %
somewhat: 17.39 %
moderate: 26.09 %
high: 28.99 %
very high: 24.64 %

Benadryl:

not at all: 3.31 %
somewhat: 22.69 %
moderate: 37.17 %
high: 26.94 %
very high: 9.89 %

Want to compare Bronkaid mist with Benadryl?

Personalize this study to your gender and age (0-99+).

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of:

Bronkaid mist (12 reports)
Benadryl (76,251 reports)

Common Benadryl side effects:

Abasia (inability to walk): 179 reports
Abdominal discomfort: 1,328 reports
Abdominal distension: 970 reports
Abdominal pain: 2,496 reports
Abdominal pain lower: 164 reports
Abdominal pain upper: 1,660 reports
Abnormal behavior: 241 reports
Abnormal dreams: 155 reports
Abortion spontaneous (naturally occurring miscarriage): 117 reports
Abscess (pus): 245 reports
Accidental overdose (therapeutic agent): 166 reports
Acne (skin problems that cause pimples): 421 reports
Activities of daily living impaired: 213 reports
Acute kidney failure: 1,599 reports
Acute myocardial infarction (acute heart attack): 123 reports
Acute respiratory failure: 157 reports
Acute upper airway obstruction (blockage occurs in the upper airway): 145 reports
Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 125 reports
Adverse drug reaction: 390 reports
Adverse event: 335 reports
Ageusia (loss of taste functions of the tongue): 117 reports
Aggression: 283 reports
Agitation (state of anxiety or nervous excitement): 958 reports
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1,049 reports
Alanine aminotransferase increased: 716 reports
Anaemia (lack of blood): 2,106 reports
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation): 106 reports
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1,416 reports
Anger: 175 reports
Angioedema (rapid swelling of the dermis): 428 reports
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 421 reports
Ankle fracture: 149 reports
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 201 reports
Aortic arteriosclerosis (hardening of the aortic arteries): 132 reports
Aphonia (inability to produce voice): 138 reports
Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 1,870 reports
Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 237 reports
Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 127 reports
Arrhythmias (irregular heartbeat): 1,497 reports
Arthritis (form of joint disorder that involves inflammation of one or more joints): 906 reports
Arthropathy: 498 reports
Arthropod bite: 130 reports
Ascites (accumulation of fluid in the abdominal cavity): 299 reports
Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 239 reports
Aspartate aminotransferase increased: 681 reports
Asthma: 1,088 reports
Atelectasis (partial or complete collapse of the lung): 441 reports
Atherosclerosis (disorder of the arteries): 225 reports
Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 808 reports
Back disorder: 115 reports
Back injury: 104 reports
Back pain: 2,942 reports
Bacteraemia (presence of bacteria in the blood): 133 reports
Bacterial infection: 207 reports
Bacterial test positive: 141 reports
Balance disorder: 832 reports
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 229 reports
Belching (release of gas from the digestive tract): 102 reports
Bipolar disorder (mood disorder): 105 reports
Bladder disorder: 118 reports
Bleeding disorders: 112 reports
Bleeding into the skin: 174 reports
Blindness: 167 reports
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 555 reports
Blood albumin decreased: 149 reports
Blood alkaline phosphatase increased: 285 reports
Blood bilirubin increased: 308 reports
Blood calcium decreased: 188 reports
Blood creatine phosphokinase increased: 112 reports
Blood creatinine increased: 507 reports
Blood glucose decreased: 219 reports
Blood glucose increased: 877 reports
Blood iron decreased: 102 reports
Blood lactate dehydrogenase increased: 180 reports
Blood magnesium decreased: 214 reports
Blood potassium decreased: 367 reports
Blood pressure diastolic decreased: 424 reports
Blood pressure diastolic increased: 212 reports
Blood pressure fluctuation: 1,243 reports
Blood pressure management: 220 reports
Blood pressure systolic increased: 1,208 reports
Blood sodium decreased: 174 reports
Blood thyroid stimulating hormone increased: 119 reports
Blood urea increased: 192 reports
Blood urine present: 429 reports
Body temperature decreased: 498 reports
Body temperature increased: 538 reports
Bone density decreased: 152 reports
Bone disorder: 553 reports
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 215 reports
Bone marrow failure: 105 reports
Bone pain: 714 reports
Bradycardia (abnormally slow heart action): 428 reports
Breast cancer: 132 reports
Breast pain: 121 reports
Breathing difficulty: 6,479 reports
Breathing - slowed or stopped: 244 reports
Broken bone: 131 reports
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1,171 reports
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 277 reports
Burning sensation: 856 reports
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 201 reports
Candidiasis (candidiasis or thrush is a fungal infection): 155 reports
Cardiac arrest: 438 reports
Cardiac disorder: 514 reports
Cardiac failure: 186 reports
Cardiac failure congestive: 658 reports
Cardiac murmur (an heart sound in valve abnormality): 170 reports
Cardiomyopathy (weakening of the heart muscle): 212 reports
Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 322 reports
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 176 reports
Cataract (clouding of the lens inside the eye): 450 reports
Cellulitis (infection under the skin): 742 reports
Cerebral infarction (less blood supply to brain resulting tissue damage): 127 reports
Chest pain: 4,445 reports
Chills (felling of cold): 2,490 reports
Cholecystitis (infection of gallbladder): 132 reports
Cholecystitis chronic (long lasting infection of gallbladder): 123 reports
Chronic kidney disease: 1,759 reports
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 536 reports
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 161 reports
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 401 reports
Colitis (inflammation of colon): 384 reports
Completed suicide (act of taking one's own life): 113 reports
Compression fracture (fracture due to pressure caused by injury): 145 reports
Confusion: 423 reports
Confusional state: 1,028 reports
Conjunctivitis (pink eye): 192 reports
Consciousness - decreased: 306 reports
Constipation: 2,006 reports
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 576 reports
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 125 reports
Coronary heart disease (narrowing or blockage of the coronary arteries): 260 reports
Cough: 3,559 reports
Coughing up blood: 279 reports
C-reactive protein increased: 460 reports
Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 530 reports
Crying: 319 reports
Crystal urine present: 122 reports
Culture urine positive: 147 reports
Cuts and puncture wounds: 185 reports
Cyst (a closed sac): 198 reports
Death: 2,216 reports
Decreased interest: 174 reports
Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 757 reports
Deformity (disfigurement): 251 reports
Dehydration (dryness resulting from the removal of water): 1,636 reports
Delirium (wild excitement): 190 reports
Delusion (a false belief or opinion): 101 reports
Dementia (madness): 106 reports
Dental caries: 336 reports
Depressed level of consciousness: 215 reports
Depressed mood: 298 reports
Depression: 2,270 reports
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 434 reports
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 156 reports
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 104 reports
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens): 144 reports
Device related infection: 227 reports
Diabetes: 622 reports
Diabetes mellitus inadequate control: 107 reports
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 119 reports
Diarrhea: 5,008 reports
Diarrhea haemorrhagic: 114 reports
Diplopia (double vision): 297 reports
Disability: 221 reports
Discomfort: 518 reports
Disease progression: 655 reports
Disease recurrence: 137 reports
Disturbance in attention: 346 reports
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 265 reports
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 191 reports
Dizziness: 4,480 reports
Drowsiness: 2,675 reports
Drug abuse and dependence: 157 reports
Drug administration error: 153 reports
Drug dependence: 287 reports
Drug effect decreased: 328 reports
Drug eruption (adverse drug reaction of the skin): 187 reports
Drug exposure during pregnancy: 203 reports
Drug hypersensitivity: 2,227 reports
Drug ineffective: 4,625 reports
Drug intolerance (drug sensitivity): 728 reports
Drug level below therapeutic: 103 reports
Drug specific antibody present: 128 reports
Drug toxicity: 165 reports
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 310 reports
Dry eyes (lack of adequate tears): 350 reports
Dry mouth: 851 reports
Dry skin: 823 reports
Dry throat: 130 reports
Dyskinesia (abnormality or impairment of voluntary movement): 376 reports
Dyspnea exertional: 469 reports
Dysstasia (difficulty in standing): 213 reports
Ear discomfort: 149 reports
Ear pain: 415 reports
Eating disorder: 241 reports
Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 133 reports
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 426 reports
Ejection fraction decreased (systolic heart failure): 150 reports
Electrocardiogram qt prolonged: 151 reports
Emotional disorder: 226 reports
Emotional distress: 922 reports
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 216 reports
Encephalopathy (functioning of the brain is affected by some agent or condition): 142 reports
Enlarged heart: 350 reports
Enthesopathy (disorder of entheses (bone attachments)): 264 reports
Eosinophil count increased: 137 reports
Erection problems: 139 reports
Erythema multiforme (a type of hypersensitivity reaction): 221 reports
Excoriation (to tear or wear off the skin of): 101 reports
Exostosis (formation of new bone on the surface of a bone): 250 reports
Extrapyramidal disorder (involuntary muscle spasms in the face and neck): 133 reports
Eye disorder: 209 reports
Eye infection: 148 reports
Eye irritation: 235 reports
Eyelid oedema (eyelids are swollen and contain excessive fluid): 136 reports
Eye pain: 434 reports
Eye pruritus (eye itching): 319 reports
Eye swelling: 589 reports
Face oedema (swelling of face): 238 reports
Facial pain: 193 reports
Faecal incontinence (a lack of control over passing stool): 149 reports
Faeces discolored: 140 reports
Failure to thrive (inadequate weight gain and physical growth in children): 117 reports
Fainting (loss of consciousness and postural tone): 898 reports
Fall: 2,630 reports
Fatigue (feeling of tiredness): 8,515 reports
Fear: 310 reports
Febrile neutropenia (fever with reduced white blood cells): 663 reports
Feeding disorder (when children refuse to eat certain food groups): 154 reports
Feeling cold: 466 reports
Feeling hot: 1,057 reports
Feeling jittery: 170 reports
Femur fracture: 218 reports
Fever: 4,324 reports
Fibromyalgia (a long-term condition which causes pain all over the body): 489 reports
Fistula (an abnormal connection or passageway between two): 217 reports
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen): 178 reports
Flatulence (flatus expelled through the anus): 382 reports
Fluid overload (too much fluid in the blood): 141 reports
Fluid retention (an abnormal accumulation of fluid in the blood): 347 reports
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 114 reports
Food allergy: 188 reports
Foot deformity (functional disability of foot): 174 reports
Foot fracture: 237 reports
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin): 108 reports
Full blood count decreased: 132 reports
Fungal infection: 363 reports
Fungal nail infection: 119 reports
Gait disturbance: 1,560 reports
Gallbladder disorder: 244 reports
Gallstones (stone formation by bile component): 493 reports
Gastric disorder (disease of stomach): 317 reports
Gastric ulcer (stomach ulcer): 585 reports
Gastritis (inflammation of stomach): 398 reports
Gastroenteritis (inflammation of stomach and intestine): 212 reports
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection): 266 reports
Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1,226 reports
Gastrointestinal disorder (functional problems of gastrointestinal tract): 468 reports
Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 466 reports
Generalised erythema (redness of the skin all over the body): 147 reports
Generalised oedema (swelling all over the body): 115 reports
General physical health deterioration (weak health status): 692 reports
Gingival bleeding (bleeding gums): 191 reports
Gingival disorder (gum disease): 121 reports
Gingival pain (gum pain): 159 reports
Gingivitis (inflammation of gums): 122 reports
Glaucoma (increased fluid pressure in the eye with vision loss): 153 reports
Glossodynia (a burning or painful sensation in the tongue): 138 reports
Gout (uric acid crystals building up in the body): 210 reports
Grand mal convulsion (a type of generalized seizure that affects the entire brain): 127 reports
Groin pain: 141 reports
Gums - swollen: 151 reports
Haematemesis (vomiting of blood): 202 reports
Haematochezia (passage of stools containing blood): 485 reports
Haematocrit decreased: 612 reports
Haematoma (collection of blood outside the blood vessels): 173 reports
Haematuria (presence of blood in urine): 315 reports
Haemoglobin decreased: 1,279 reports
Haemolytic anaemia (anaemia due to haemolysis): 116 reports
Haemorrhage (bleeding): 587 reports
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 425 reports
Hair color changes: 275 reports
Hair disorder: 231 reports
Hair loss: 1,662 reports
Hallucination, auditory (perceiving sounds without auditory stimulus): 115 reports
Hallucinations (sensations that appear real but are created by your mind): 538 reports
Headache (pain in head): 6,684 reports
Head discomfort: 119 reports
Head injury: 1,491 reports
Hearing loss: 205 reports
Heart attack: 740 reports
Heart palpitations (feelings or sensations that your heart is pounding or racing): 1,265 reports
Heart rate decreased: 965 reports
Heart rate increased: 1,993 reports
Heart rate irregular: 616 reports
Heavy or prolong menstrual bleeding: 135 reports
Hemiparesis (weakness on one side of the body): 185 reports
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 115 reports
Hepatic cyst: 154 reports
Hepatic enzyme increased: 520 reports
Hepatic failure (liver failure): 180 reports
Hepatic steatosis (fatty liver disease): 256 reports
Hepatitis (inflammation of the liver): 168 reports
Hepatomegaly (abnormal enlargement of the liver): 168 reports
Hereditary angioedema (recurrent episodes of severe swelling): 227 reports
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 206 reports
Herpes simplex (herpes simplex is a common viral infection): 110 reports
Herpes zoster: 940 reports
Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 297 reports
High blood cholesterol: 873 reports
High blood pressure: 4,941 reports
Hip fracture: 215 reports
Hoarseness or changing voice: 564 reports
Hospitalisation: 359 reports
Hot flush (sudden feelings of heat): 780 reports
Hyperaesthesia: 114 reports
Hypercalcaemia (elevated calcium (ca+) level in the blood): 232 reports
Hyperglycemia (high blood sugar): 320 reports
Hyperhidrosis (abnormally increased sweating): 1,294 reports
Hyperkalemia (damage to or disease of the kidney): 259 reports
Hyperlipidaemia (presence of excess lipids in the blood): 224 reports
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 124 reports
Hypersensitivity: 3,251 reports
Hyperthyroidism (over activity of the thyroid gland): 130 reports
Hypoacusis (loss of hearing): 183 reports
Hypoaesthesia (reduced sense of touch or sensation): 2,082 reports
Hypoaesthesia oral (reduced sense of touch or sensation in mouth): 279 reports
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 120 reports
Hypoglycemia (low blood sugar): 216 reports
Hypokalemia (low potassium): 518 reports
Hypokinesia (decreased bodily movement): 179 reports
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 215 reports
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 393 reports
Hypophagia (reduced food intake): 325 reports
Hypotension (abnormally low blood pressure): 3,362 reports
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 337 reports
Idiopathic pulmonary fibrosis (chronic lung disease): 187 reports
Ill-defined disorder: 348 reports
Immune system disorder: 121 reports
Immunodeficiency: 194 reports
Impaired gastric emptying: 140 reports
Impaired healing: 504 reports
Impaired work ability: 114 reports
Incontinence (lack of moderation or self-control): 145 reports
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone): 128 reports
Indigestion: 1,000 reports
Infection: 1,440 reports
Inflammation: 588 reports
Influenza like illness: 935 reports
Infusion related reaction: 4,172 reports
Infusion site erythema (reddening of the skin at infusion site): 144 reports
Infusion site extravasation (flow of (blood or lymph) from infusion site): 144 reports
Infusion site pain: 211 reports
Infusion site swelling: 123 reports
Initial insomnia (feeling of inadequate or poor-quality sleep): 103 reports
Injection site bruising: 235 reports
Injection site erythema (redness at injection site): 532 reports
Injection site haemorrhage (bleeding from injection site): 179 reports
Injection site pain: 886 reports
Injection site pruritus (severe itching at injection site): 458 reports
Injection site rash: 142 reports
Injection site reaction: 379 reports
Injection site swelling: 376 reports
Injection site urticaria (rash of round, red welts on the skin at injection site): 183 reports
Injection site warmth: 102 reports
Injury: 1,016 reports
Insomnia (sleeplessness): 3,197 reports
Intentional overdose: 117 reports
International normalised ratio increased: 189 reports
Interstitial lung disease: 183 reports
Interstitial nephritis (inflammation of the kidney): 184 reports
Intervertebral disc degeneration (spinal disc degeneration): 320 reports
Intervertebral disc disorder (spinal disc disorder): 112 reports
Intervertebral disc protrusion (spinal disc protrusion): 447 reports
Intestinal obstruction: 334 reports
Irritability: 446 reports
Irritable bowel syndrome: 218 reports
Itching: 5,766 reports
Jaundice - yellow skin (a yellowish pigmentation of the skin): 153 reports
Jaw disorder (jaw disease): 125 reports
Joint effusion (presence of extra fluid in joint covering): 167 reports
Joint injury: 174 reports
Joint pain: 4,289 reports
Joint range of motion decreased (disease of joint movement): 145 reports
Joint stiffness: 359 reports
Joint swelling: 1,219 reports
Kidney infection: 225 reports
Kidney stones: 511 reports
Lacrimation increased: 313 reports
Laryngitis (inflammation of the larynx): 132 reports
Leukocytosis (increased white blood cells): 223 reports
Leukopenia (less number of white blood cells in blood): 444 reports
Limb discomfort (discomfort in leg): 256 reports
Limb injury: 237 reports
Lip swelling: 617 reports
Liver disorder (liver diseases): 115 reports
Localised infection (infection at the single location): 237 reports
Local swelling (swelling at the site of some application of substance or injury): 218 reports
Loose tooth: 167 reports
Loss of consciousness: 1,276 reports
Lower limb fracture: 110 reports
Lower respiratory tract infection: 377 reports
Low tissue oxygen: 459 reports
Lung disorder (lung disease): 293 reports
Lung infection: 198 reports
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 258 reports
Lung neoplasm (tumour of lung): 165 reports
Lung neoplasm malignant (cancer tumour of lung): 125 reports
Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 592 reports
Lymphocyte count decreased: 653 reports
Lymphocyte percentage decreased: 111 reports
Lymphoedema (localized fluid retention and tissue swelling): 110 reports
Malaise (a feeling of general discomfort or uneasiness): 3,593 reports
Malignant neoplasm progression (cancer tumour came back): 407 reports
Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 175 reports
Mania (a state of abnormally elevated or irritable mood): 128 reports
Maternal exposure during pregnancy (use of substance during pregnancy): 277 reports
Melaena (the passage of black, tarry stools): 104 reports
Memory loss: 1,502 reports
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 332 reports
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 168 reports
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 404 reports
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 122 reports
Metastases to bone (cancer spreads to bone): 315 reports
Metastases to central nervous system (cancer spreads to central nervous system): 130 reports
Metastases to liver (cancer spreads to liver): 175 reports
Metastases to lung (cancer spreads to lung): 192 reports
Metastases to spine (cancer spreads to spine): 101 reports
Micturition urgency (urgency to pass the urine): 159 reports
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night): 206 reports
Migraine (headache): 1,293 reports
Mitral valve incompetence (inefficient heart valve): 277 reports
Mobility decreased (ability to move is reduced): 626 reports
Mood swings (an extreme or rapid change in mood): 406 reports
Mouth ulcers: 287 reports
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 242 reports
Movement - uncontrolled or slow: 164 reports
Movement - uncoordinated: 187 reports
Mucosal inflammation (infection of mucous membrane): 362 reports
Multi-organ failure (multisystem organ failure): 241 reports
Multiple allergies (allergy to multiple agents): 137 reports
Multiple myeloma (cancer of the plasma cells): 243 reports
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 304 reports
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 593 reports
Muscle aches (muscle pain): 1,336 reports
Muscle spasms (muscle contraction): 1,635 reports
Muscle strain (an injury to a muscle in which the muscle fibres tear): 132 reports
Muscle tightness: 208 reports
Muscle twitching: 311 reports
Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 271 reports
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 178 reports
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 158 reports
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 834 reports
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 985 reports
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 844 reports
Nasopharyngitis (inflammation of the nasopharynx): 2,310 reports
Nausea (feeling of having an urge to vomit): 8,198 reports
Nausea and vomiting: 4,772 reports
Neck pain: 893 reports
Neoplasm malignant (cancer tumour): 310 reports
Neoplasm progression (growth of tumour): 127 reports
Nephrogenic anaemia (anaemia due to kidney disease): 262 reports
Nerve injury: 117 reports
Nervousness: 599 reports
Nervous system disorder (a general class of medical conditions affecting the nervous system): 165 reports
Neuralgia (pain in one or more nerves): 434 reports
Neuropathy peripheral (surface nerve damage): 1,015 reports
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 418 reports
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell): 185 reports
Nightmares (unpleasant dreams): 205 reports
Night sweats (sweating in night): 369 reports
Nodule (a small rock or mineral cluster): 177 reports
Nosebleed (bleeding from nose): 775 reports
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 124 reports
Obstructive airways disorder (a progressive disease that makes it hard to breathe): 139 reports
Ocular hyperaemia (an abnormally large amount of blood in eye): 305 reports
Oedema (fluid collection in tissue): 629 reports
Oedema peripheral (superficial swelling): 1,489 reports
Oesophagitis (inflammation of oesophagus): 219 reports
Oral candidiasis (fungal infection of mouth): 188 reports
Oral discomfort (pain or irritation in mouth): 127 reports
Oral disorder (mouth disease): 139 reports
Oral herpes (viral infection of mouth): 299 reports
Oral pain: 529 reports
Oropharyngeal pain: 1,345 reports
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 177 reports
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 685 reports
Osteolysis (dissolution of bone): 130 reports
Osteomyelitis (infection of bone): 420 reports
Osteonecrosis of jaw (death of bone of jaw): 690 reports
Osteopenia (a condition where bone mineral density is lower than normal): 397 reports
Osteoporosis (bones weak and more likely to break): 627 reports
Otitis (ear infection): 301 reports
Ovarian cysts (fluid filled sacs of the ovary): 182 reports
Overdose: 689 reports
Oxygen saturation decreased: 1,676 reports
Pain: 5,865 reports
Pain in extremity: 2,959 reports
Pain in jaw: 693 reports
Pain of skin: 204 reports
Paleness (unusual lightness of skin colour): 412 reports
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome): 112 reports
Pancreatitis (inflammation of pancreas): 311 reports
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 494 reports
Panic disorder: 411 reports
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 1,992 reports
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect): 262 reports
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 143 reports
Paroxysmal supraventricular tachycardia: 146 reports
Pathological fracture (broken bone caused by disease): 135 reports
Pelvic pain: 123 reports
Pericardial effusion (fluid around the heart): 251 reports
Pericarditis (inflammation of the pericardium): 102 reports
Periodontitis (inflammation of the tissue around the teeth): 158 reports
Peripheral coldness: 161 reports
Peripheral swelling: 1,609 reports
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 414 reports
Pharyngitis (inflammation of the pharynx, causing a sore throat): 221 reports
Pharyngolaryngeal pain: 107 reports
Photophobia (extreme sensitivity to light): 173 reports
Photosensitivity reaction: 173 reports
Physical disability: 113 reports
Platelet count increased: 177 reports
Pleural effusion (water on the lungs): 897 reports
Pneumonia: 2,861 reports
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 144 reports
Pneumonia viral: 180 reports
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 158 reports
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 402 reports
Poor quality sleep: 241 reports
Poor venous access: 277 reports
Post procedural complication: 153 reports
Pre-existing condition improved: 129 reports
Pressure ulcer: 135 reports
Presyncope: 195 reports
Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 162 reports
Procedural pain: 115 reports
Productive cough: 745 reports
Protein - urine: 165 reports
Protein urine present: 148 reports
Pruritus generalised (generalized itching): 494 reports
Psoriasis (immune-mediated disease that affects the skin): 354 reports
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 333 reports
Psychological trauma: 201 reports
Psychomotor hyperactivity (feelings of extreme restlessness): 135 reports
Psychotic disorder: 288 reports
Pulmonary congestion (congestion in the lungs): 197 reports
Pulmonary embolism (blockage of the main artery of the lung): 794 reports
Pulmonary hypertension (increase in blood pressure in the lung artery): 216 reports
Pulmonary mass: 141 reports
Pulmonary oedema (fluid accumulation in the lungs): 471 reports
Pulse absent: 103 reports
Purulent discharge (discharge that contains pus): 148 reports
Quality of life decreased: 130 reports
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 110 reports
Rales (an abnormal respiratory sound characterized by fine crackles): 124 reports
Rash erythematous (redness of the skin): 743 reports
Rashes (redness): 7,523 reports
Rash macular (small, flat red spots): 392 reports
Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 215 reports
Rash papular (redness with papule): 242 reports
Rash pruritic (redness with itching): 963 reports
Rectal haemorrhage (bleeding from anus): 376 reports
Red blood cell count decreased: 497 reports
Red blood cell sedimentation rate increased: 206 reports
Red blood cells urine positive: 166 reports
Red cell distribution width increased: 248 reports
Renal cyst (kidney cyst): 210 reports
Renal disorder (kidney disease): 207 reports
Renal failure acute (rapid kidney dysfunction): 484 reports
Renal failure chronic (long lasting kidney dysfunction): 203 reports
Renal impairment (severely reduced kidney function): 436 reports
Renal injury (kidney injury): 511 reports
Renal pain (kidney pain): 151 reports
Renal tubular necrosis (death of kidney tubules): 130 reports
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 532 reports
Respiratory disorder (respiratory disease): 320 reports
Respiratory distress (difficulty in breathing): 467 reports
Respiratory rate increased (excess breathing rate/min): 320 reports
Respiratory tract congestion (blockage on respiratory system): 180 reports
Respiratory tract infection: 234 reports
Restless leg syndrome (a powerful urge to move your legs): 280 reports
Retching (strong involuntary effort to vomit): 254 reports
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 117 reports
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 1,186 reports
Rheumatoid nodule (a local swelling or tissue lump with rheumatoid disease): 163 reports
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 212 reports
Rib fracture: 311 reports
Rickets (softening of bones): 140 reports
Road traffic accident: 397 reports
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 195 reports
Scab (a hard coating on the skin formed during the wound healing): 108 reports
Scar: 260 reports
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 173 reports
Scoliosis (a medical condition in which a person's spine is curved from side to side): 164 reports
Scratch: 240 reports
Seasonal allergy (allergic condition due to certain season): 277 reports
Secretion discharge: 109 reports
Sedation: 254 reports
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 468 reports
Sensation of foreign body: 167 reports
Sensory disturbance (sense disturbance): 165 reports
Sepsis (a severe blood infection that can lead to organ failure and death): 964 reports
Septic shock (shock due to blood infection): 190 reports
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 102 reports
Sinus bradycardia (an unusually slow heartbeat due to heart disease): 103 reports
Sinus congestion (blockage of sinus): 315 reports
Sinus disorder (disease of sinus): 359 reports
Sinus headache (headache caused by sinus infections): 143 reports
Sinusitis (inflammation of sinus): 1,743 reports
Sinusitis - chronic: 125 reports
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 323 reports
Skin blushing/flushing (a sudden reddening of the face, neck): 2,541 reports
Skin burning sensation: 347 reports
Skin - clammy: 199 reports
Skin discoloration: 576 reports
Skin discoloration - bluish (bluish colour of skin): 216 reports
Skin disorder (skin disease): 332 reports
Skin exfoliation (removal of the oldest dead skin cells): 525 reports
Skin fissures (a crack in the skin): 144 reports
Skin infection: 148 reports
Skin irritation: 121 reports
Skin necrosis (skin damage): 162 reports
Skin reaction: 116 reports
Skin ulcer: 436 reports
Sleep apnea syndrome: 425 reports
Sleep disorder: 587 reports
Small intestinal obstruction (blockage in small intestine): 175 reports
Sneezing: 289 reports
Soft tissue disorder (disease of soft tissue): 185 reports
Speech disorder: 483 reports
Speech impairment (adult) (inability to speak (adult)): 652 reports
Spinal column stenosis (narrowing of spinal column): 133 reports
Spinal compression fracture (fracture due to spinal compression on bone): 134 reports
Spinal disorder (disease of spine a back bone): 122 reports
Spinal osteoarthritis (joint cartilage loss in spine): 397 reports
Splenomegaly (enlargement of spleen): 196 reports
Sputum discolored: 159 reports
Stable angina (a constant chest pain): 168 reports
Staphylococcal infection (an infection with staphylococcus bacteria): 417 reports
Stomatitis (inflammation of mucous membrane of mouth): 776 reports
Stress and anxiety: 4,277 reports
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 691 reports
Suicidal ideation: 611 reports
Suicide attempt: 318 reports
Surgery: 215 reports
Swallowing difficulty: 1,258 reports
Swallowing pain or burning: 105 reports
Sweating increased (excess sweating): 111 reports
Swelling: 1,393 reports
Swelling face: 1,066 reports
Swollen tongue (swelling of tongue): 603 reports
Synovial cyst (cyst of joint filled with synovial fluid): 181 reports
Synovitis (inflammation of the synovial membrane): 513 reports
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 196 reports
Tachypnea: 133 reports
Tardive dyskinesia (a disorder that involves involuntary movements): 152 reports
Taste - impaired: 545 reports
Temperature intolerance (inability to go in temperature): 190 reports
Tenderness (pain or discomfort when an affected area is touched): 283 reports
Tendonitis (a condition that causes pain and swelling of tendons): 352 reports
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon): 299 reports
The flu (the flu is caused by an influenza virus): 1,151 reports
Therapeutic response decreased (less preventive response): 414 reports
Therapeutic response unexpected: 396 reports
Thirst: 128 reports
Throat irritation: 1,086 reports
Throat tightness: 832 reports
Thrombocytopenia (decrease of platelets in blood): 1,840 reports
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 145 reports
Thrombosis (formation of a blood clot inside a blood vessel): 540 reports
Thyroid diseases: 126 reports
Tinnitus (a ringing in the ears): 423 reports
Tongue disorder (disease of tongue): 350 reports
Tooth abscess (pus formation in tooth): 451 reports
Toothaches (tooth pain): 322 reports
Tooth disorder (tooth disease): 524 reports
Tooth extraction: 281 reports
Tooth fracture: 185 reports
Tooth loss: 146 reports
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 253 reports
Tremor (trembling or shaking movements in one or more parts of your body): 1,889 reports
Tricuspid valve incompetence (inefficient heart valve): 169 reports
Trismus (reduced opening of the jaws): 135 reports
Tumor: 345 reports
Type 2 diabetes: 289 reports
Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 218 reports
Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter): 101 reports
Unresponsive to stimuli: 245 reports
Upper-airway cough syndrome: 167 reports
Upper respiratory tract infection: 615 reports
Urinary incontinence (inability to control the flow of urine and involuntary urination): 409 reports
Urinary retention (the inability to completely or partially empty the bladder): 330 reports
Urinary sediment present: 109 reports
Urinary tract infection: 2,123 reports
Urination - excessive at night: 135 reports
Urination - painful: 493 reports
Urine abnormality: 385 reports
Urine ketone body present: 146 reports
Urine leukocyte esterase positive: 218 reports
Urticaria (rash of round, red welts on the skin that itch intensely): 4,525 reports
Uterine leiomyoma (uterine benign tumour derived from smooth muscle): 130 reports
Vaginal bleeding: 202 reports
Vaginal infection: 104 reports
Vasculitis (inflammation of a blood vessel or blood vessels): 184 reports
Ventricular extrasystoles (premature cardiac contraction): 115 reports
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 153 reports
Viral infection: 339 reports
Viral upper respiratory tract infection: 108 reports
Vision blurred: 1,210 reports
Visual acuity reduced (reduced clearness of vision): 186 reports
Visual impairment: 647 reports
Vitreous floaters (spots before the eyes): 138 reports
Weakness: 4,559 reports
Weight decreased: 3,000 reports
Weight fluctuation: 118 reports
Weight increased: 2,388 reports
Weight loss: 234 reports
Wheezing (a high-pitched whistling sound made while you breath): 804 reports
White blood cell count decreased: 1,334 reports
White blood cell count increased: 536 reports
White blood cells urine positive: 218 reports
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 155 reports
Wound: 263 reports
Wound infection: 104 reports

How the study uses the data?

The study is based on epinephrine and diphenhydramine hydrochloride (the active ingredients of Bronkaid mist and Benadryl, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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