Chantix vs Wellbutrin xl - from FDA reports

This is a side effect comparison of Chantix and Wellbutrin xl. The study is created by eHealthMe based on reports from FDA, and is updated regularly.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.

On Mar, 04, 2019

207,495 people who take Chantix and Wellbutrin xl are studied.

Number of reports submitted per year:

Chantix vs Wellbutrin xl drug comparison reports.

Drugs in this study:

  • Chantix (varenicline tartrate)
  • Wellbutrin Xl (bupropion hydrochloride)

eHealthMe real world results:

Most common side effects:

  1. Drug Ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Headache (pain in head)
  4. Fatigue (feeling of tiredness)
  5. Insomnia (sleeplessness)
  6. Pain
  7. Dizziness
  8. Dyspnoea (difficult or laboured respiration)
  9. Completed Suicide (act of taking one's own life)
  10. Vomiting
Wellbutrin Xl:
  1. Nausea (feeling of having an urge to vomit)
  2. Abnormal Dreams
  3. Insomnia (sleeplessness)
  4. Suicidal Ideation
  5. Drug Ineffective
  6. Vomiting
  7. Headache (pain in head)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Aggression
  10. Suicide Attempt

Most common side effects experienced by people in long term use:

  1. Drug Ineffective
  2. Insomnia (sleeplessness)
  3. Headache (pain in head)
  4. Pain
  5. Nausea (feeling of having an urge to vomit)
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  7. Dizziness
  8. Fatigue (feeling of tiredness)
  9. Hypertension (high blood pressure)
  10. Tremor (trembling or shaking movements in one or more parts of your body)
Wellbutrin Xl:
  1. Suicide Attempt
  2. Aggression
  3. Intentional Overdose
  4. Suicidal Ideation
  5. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  6. Abnormal Dreams
  7. Nausea (feeling of having an urge to vomit)
  8. Loss Of Consciousness
  9. Insomnia (sleeplessness)
  10. Abnormal Behaviour

What are the drugs?

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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