Cytoxan vs. Aredia


We compare the side effects and drug effectiveness of Cytoxan and Aredia. The study is created by eHealthMe based on reports of 120,563 people who take Cytoxan and Aredia, and is updated regularly.

What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on cyclophosphamide and pamidronate disodium (the active ingredients of Cytoxan and Aredia, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered.

What is Cytoxan?

Cytoxan has active ingredients of cyclophosphamide. It is often used in breast cancer. (latest outcomes from Cytoxan 12,520 users)

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. (latest outcomes from Aredia 14,912 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 16, 2019

120,563 people who take Cytoxan and Aredia are studied.

Number of reports submitted per year:

Cytoxan vs Aredia drug comparison reports.

Drugs in this study:

  • Aredia (pamidronate disodium)
  • Cytoxan (cyclophosphamide)

Most common side effects:

  1. Pain
  2. Osteonecrosis (death of bone)
  3. Osteonecrosis Of Jaw (death of bone of jaw)
  4. Anxiety
  5. Bone Disorder
  6. Tooth Extraction
  7. Osteomyelitis (infection of bone)
  8. Anaemia (lack of blood)
  9. Injury
  10. Pain In Jaw
  1. Febrile Neutropenia (fever with reduced white blood cells)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Pyrexia (fever)
  4. Alopecia (absence of hair from areas of the body)
  5. Nausea (feeling of having an urge to vomit)
  6. Pneumonia
  7. Diarrhoea
  8. Anaemia (lack of blood)
  9. Thrombocytopenia (decrease of platelets in blood)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

Most common side effects experienced by people in long term use:

  1. Osteonecrosis (death of bone)
  2. Bone Disorder
  3. Pain
  4. Tooth Extraction
  5. Osteomyelitis (infection of bone)
  6. Osteonecrosis Of Jaw (death of bone of jaw)
  7. Pain In Jaw
  8. Anxiety
  9. Impaired Healing
  10. Anaemia (lack of blood)
  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Pneumonia
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Anaemia (lack of blood)
  5. Disease Progression
  6. Pyrexia (fever)
  7. Febrile Neutropenia (fever with reduced white blood cells)
  8. Pain
  9. Thrombocytopenia (decrease of platelets in blood)
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

Drug effectiveness:

  • not at all: 5.26 %
  • somewhat: 21.05 %
  • moderate: 31.58 %
  • high: 21.05 %
  • very high: 21.05 %
  • not at all: 5.68 %
  • somewhat: 23.86 %
  • moderate: 31.82 %
  • high: 23.86 %
  • very high: 14.77 %

Do you take Cytoxan or Aredia?

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WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.